New Issue of the Journal Current Pharmaceutical Biotechnology

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.


Following are the articles from the journal Current Drug Targets, 16 issue 6:

Article: Intravital Microscopy Imaging Approaches for Image-Guided Drug Delivery Systems

Author(s): Dickson K. Kirui and Mauro Ferrari


Article: Recent Advances in Optical Molecular Imaging and its Applications in Targeted Drug Delivery

Author(s):  Xibo Ma, Hui Hui, Wenting Shang, Xiaohua Jia, Xin Yang and Jie Tian


Article: Preparation of Multifunctional Nanoprobes for Tumor-Targeted Fluorescent Imaging and Therapy

Author(s): Mi Zhou, Xiao Xiao, Adnan A. Kadi, Hoong-kun Fun, Jinbo Li and Yan Zhang


Article: Multiscale Imaging of Nanoparticle Drug Delivery

Author(s): Lawrence W. Dobrucki, Dipanjan Pan and Andrew M. Smith


Article: Opportunities for Photoacoustic-Guided Drug Delivery

Author(s):  Jun Xia, Chulhong Kim and Jonathan F. Lovell


Article: PET and SPECT Imaging for the Acceleration of Anti-Cancer Drug Development

Author(s): Christopher R.T. Hillyar, James C. Knight, Katherine A. Vallis and Bart Cornelissen


Article: Image-Guided Drug Delivery with Single-Photon Emission Computed Tomography: A Review of Literature

Author(s): Rubel Chakravarty, Hao Hong and Weibo Cai


Article: Matching Chelators to Radiometals for Positron Emission Tomography Imaging- Guided Targeted Drug Delivery

Author(s):  Huaifu Deng, Hui Wang and Zibo Li


Article: Tumor Targeting Using Radiolabeled Antibodies for Image-Guided Drug Delivery

Author(s):  Mark Rijpkema, Otto C. Boerman and Wim. J.G. Oyen


Article: Recent Advances in Molecular Image-Guided Cancer Radionuclide Therapy

Author(s):  Duo Gao, Xianlei Sun, Liquan Gao and Zhaofei Liu


Article: Molecular Imaging of Therapeutic Potential of Reporter Probes

Author(s):  Bhushan Thakur, Subhoshree Chatterjee, Smrita Chaudhury and Pritha Ray


Article: Image Guidance in Stem Cell Therapeutics: Unfolding the Blindfold

Author(s):  Amirali B. Bukhari, Shruti Dutta and Abhijit De


Article: Biomedical Imaging in Implantable Drug Delivery Systems

Author(s):  Haoyan Zhou, Christopher Hernandez, Monika Goss, Anna Gawlik and Agata A. Exner


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Video presentation on the journal ‘Recent Patents on Anti-Cancer Drug Discovery ‘

Recent Patents on Anti-Cancer Drug Discovery publishes review and research articles, and guest edited thematic issues on recent patents in the field of anti-cancer drug discovery.

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Recently Published Issue of the Journal Current Pharmaceutical Biotechnology

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal contains a series of timely in-depth reviews, research articles and letters written by leaders in the field covering a range of current topics in both pre-clinical and clinical areas of Pharmaceutical Biotechnology. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Following are the articles from the journal Current Pharmaceutical Biotechnology, 16 issue 9:

Article: Treatment of Pancreatic Cancer with Pharmacological Ascorbate

Author(s): John A. Cieslak and Joseph J. Cullen


Article: Immunotherapy Approaches in Cancer Treatment

Author(s): Pavel Klener, Pavel Otahal, Lucie Lateckova and Pavel Klener


Article: Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells

Author(s): Pier M. Biava, Silvia Canaider, Federica Facchin, Eva Bianconi, Liza Ljungberg, Domenico Rotilio, Fabio Burigana and Carlo Ventura


Article: Getting an Insight into the Complexity of Major Chronic Inflammatory and Degenerative Diseases: A Potential New Systemic Approach to Their Treatment

Author(s): Pier M. Biava and Guido Norbiato


Article: The PI3K-AKt-mTOR Pathway and New Tools to Prevent Acquired Hormone Resistance in Breast Cancer

Author(s):  Andrea Nicolini, Paola Ferrari, Lucie Kotlarova, Giuseppe Rossi and Pier M. Biava


Article: Parametric Investigation of Batch Adsorption of Proteins onto Polymeric Particles

Author(s): Melvin X.L. Tan, Dominic Agyei, Sharadwata Pan and Michael K. Danquah


Article: Sildenafil Improves Vascular Endothelial Structure and Function in Renovascular Hypertension

Author(s): Bernah M. Fahning, Ananda T. Dias, Jairo P. Oliveira, Agata L. Gava, Marcella L. Porto, Isabele B.S. Gomes, Breno V. Nogueira, Bianca P. Campagnaro, Thiago M.C. Pereira, Elisardo C. Vasquez, Camille M. Balarini and Silvana S. Meyrelles


Article: Delta Np63 alpha – Responsive microRNA Modulate the Expression of Metabolic Enzymes

Author(s):  Edward A. Ratovitski


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Free to download, Open Access Plus article from the journal ‘Endocrine, Metabolic & Immune Disorders’

The article entitled Neutrophil Derived Microvesicles: Emerging Role of a Key Mediator to the Immune Response in the journal Endocrine, Metabolic & Immune Disorders – Drug Targets, 2014, 14, 210-217 is now open for all to view and access.


In response to infection and trauma, exquisite control of the innate inflammatory response is necessary to promote an anti-microbial response and minimize tissue injury. Over the course of the host response, activated leukocytes are essential for the initial response and can later become unresponsive or undergo apoptosis. Leukocytes, along the continuum of activation to apoptosis, have been shown to generate microvesicles. These vesicles can range in size from 0.1 to 1.0 μm and can retain proteins, RNA and DNA of their parent cells. Importantly, neutrophil-derived microvesicles (NDMV) are robustly increased under inflammatory conditions. The aim of this review is to summarize the research to date upon NDMVs. This will include describing under which disease states NDMVs are increased, mechanisms underlying formation, and the impact of these vesicles upon cellular targets. Altogether, increased awareness of NDMVs during the host innate response may allow for diagnostic tools as well as potential novel therapies during infection and trauma.



Chinese abstracts are available in the new issue of the journal Current Medicinal Chemistry

Current Medicinal Chemistry,

Volume 22 – Number 28


Angiotensin II Type 1 Receptor Binding Molecule ATRAP as a Possible Modulator of Renal Sodium Handling and Blood Pressure in Pathophysiology, 22(28): 3210 – 3216

View Abstract 中文摘要 Purchase Online View on PubMed Order Reprints Order Eprints Rights and Permissions

Synthesis of Porphyrin, Chlorin and Phthalocyanine Derivatives by Azide-Alkyne Click Chemistry, 22(28): 3217 – 3254Samir Acherar, Ludovic Colombeau, Celine Frochot and Regis Vanderesse.

View Abstract 中文摘要 Purchase Online View on PubMed Order Reprints Order Eprints Rights and Permissions

Progress in the Search for New Dopamine Transporter Inhibitors, 22(28): 3255 – 3277

View Abstract 中文摘要 Purchase Online View on PubMed Order Reprints Order Eprints Rights and Permissions

PET and SPECT Radiotracers for Alzheimer’s Disease, 22(28): 3278 – 3304 

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Active free trials in the universities around the world


Motilal Nehru National Institute of Technology Allahabad, Allahabad (MNNIT) is an Institute with total commitment to quality and excellence in academic pursuits. It was established as one of the seventeen Regional Engineering Colleges of India in the year 1961 as a joint enterprise of Government of India and Government of Uttar Pradesh, and was an associated college of University of Allahabad, which is the third oldest university in India.

For a short duration of two years (2000-2002), the Institute was affiliated to U.P. Technical University. With over 45 years of experience and achievements in the field of technical education, having traversed a long way, on June 26, 2002 MNREC was transformed into National Institute of Technology and Deemed University fully funded by Government of India.


Set in a picturesque landscape at the foothills of the Western Ghats, National Institute of Technology Calicut (NITC) is located about 22 kilometers north-east of Calicut City. National Institute of Technology Calicut is a Technical Institution of national importance set up by an Act of parliament(Act 29 of 2007) namely, the National Institute of technology Act 2007, which received the assent of the President of India on 5th June,2007. The provision of the Act have come into force with effect from 15th August, 2007 as per Notification S.O.1384(E) dated 9th August, 2007 of the MHRD(Dept. of Higher Education),New Delhi. As per the provision of the said Act, this Institution runs on non-profitable basis.

Institute of Oncology Research, Switzerland

The (lOR) Institute of Oncology Research is part of the Research Division of the Oncology Institute of Southern Switzerland (IOSI), the comprehensive cancer center of the Ente Ospedaliero Cantonale (EOC), and is the main facility for basic and translational research at the IOSI. The Institute was established in 2003 formerly as the IOSI Laboratory of Experimental Oncology and is located within the Institute for Research in Biomedicine (IRB) in Bellinzona, Canton Ticino.

Tadulako University, Indonesia

Tadulako University (Indonesian: Universitas Tadulako) is the only public university in Palu, Central Sulawesi, Indonesia. It was established on May 1, 1981 after being an affiliate of Hasanuddin University of Makassar for several years. Its current rector is Muhammad Basir.

The Tadulako University (Untad) in Palu host 9 Faculties, enrolled by 22.000 student bodies (2011) and served by 1057 academic staff. Deriving from a small private education institution (1963), Tadulako University was established as public state university in 1981. Located on an outer island, Tadulako University today plays an important role in developing higher education in the eastern part of Indonesia.

Nanjing University of Chinese Medicine, China

Founded in 1954, Nanjing University of Chinese Medicine (NUCM) is one of the oldest institutions in China. It is highly regarded as the birthplace of TCM higher education. The university is one of the WHO Collaborative Centers on Traditional Medicine, the International Acupuncture Training Center specified by the Ministry of Health of China, and one of the first few of TCM universities approved by the Ministry of Education of China to train international students. The university currently offers students three types of degrees: Bachelor’s, Master’s, and Doctoral degrees. At present, the University is running 25 bachelor’s programs, 44 master’s programs, 25 doctoral programs and 3 postdoctoral stations. Affiliated with the University, are 22 clinical hospitals, 5 hospitals of Integrated TCM and Western Medicine and hundreds of teaching clinics. The university takes an active part in international cooperation and academic exchange. Early in the year of 1993, it initiated a joint Bachelor program with the Royal Melbourne Institute of Technology of Australia. At present, there are about 18,000 students studying on campus, including over 2000 students who are studying Master’s and Doctoral degrees, along with over 1000 overseas students.

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