Editor’s Choice Article | Synthesis, Molecular Modeling and Biological Evaluation of 5-arylidene- N,N-diethylthiobarbiturates as Potential α-glucosidase Inhibitors

 

Author(s): Momin Khan*, Sehrish Khan, Amir Ul Mulk, Anis Ur Rahman, Abdul Wadood, Sulaiman Shams, Muhammad Ashraf, Jameel Rahman, Iltaf Khan, Abdul Hameed, Zahid Hussain, Abbas Khan, Khair Zaman, Khalid M. Khan, Shahnaz Perveen.

Journal Name: Medicinal Chemistry

 

Barbituric acid derivatives are a versatile group of compounds which are identified as potential pharmacophores for the treatment of anxiety, epilepsy and other psychiatric disorders. They are also used as anesthetics and have sound effects on the motor and sensory functions. Barbiturates are malonylurea derivatives with a variety of substituents at C-5 position showing resemblance with nitrogen and sulfur containing compounds like thiouracil which exhibited potent anticancer and antiviral activities. Recently, barbituric acid derivatives have also received great interest for applications in nanoscience. Read out full article here: http://www.eurekaselect.com/165349/article

Press Release | Bentham Science Partnership Brings Education Materials to Africa and Middle East

 

Bentham Science Publishers is now an exclusive partner with Panworld Education in the Middle East and Africa. This exclusive partnership enables Panworld Education to give researchers in the Middle East and Africa access to science, technology, and medical (STM) journals, books, and eBooks, which has been a long term goal for the company.

Through Panworld Education, Bentham Science will be offering access to many of their high impact journals, like their popular medical subspecialties series, over one hundred and twenty subscription journals, and over six hundred ebook collections.

Together, Bentham Science and Panworld Education will also support various academic conferences in the Middle East and Africa, allowing even greater access to new scientific and medical research.

 

 

Read full press release to find out more at: http://bit.ly/2GCretu

Press Release | Fighting to Find Relief: A new study shows decrease in depression in cancer patients

 

A New Study Published by Bentham Science Shows Support Groups and Educational Resources Can Decrease Depression in Breast Cancer Patients

 

1 in 8 women in the US will be diagnosed with breast cancer in their lifetime.

In 2018 alone, an estimated 266,120 new cases of breast cancer were diagnosed nationwide. As the numbers of new cases grow, the support network of women who suffer from breast cancer grows. In their ever-increasing numbers, the many women diagnosed with this disease face an arduous physical and emotional journey on their road to recovery, and along the way, many suffer from depression, anxiety, and body image issues.

Regardless of the prevalence of body image issues, anxiety, and depression in women who are suffering from breast cancer, there aren’t a lot of resources available for those afflicted. A recent study suggests it’s time to right that wrong. The study, published by Bentham Science, focused on Dr. Fausto Meriggi and his team at Fondazione Poliambulanza di Brescia who studied the effects of psychotherapeutic and educational groups on depression, anxiety, and body image issues among women suffering from breast cancer.

This study was published in Reviews on Recent Clinical Trials, a journal published by Bentham Science.  Bentham Science continues their work in the Middle East and North Africa, bringing education materials and increased accessibility to the region.

 

Read full press release to find out more at: http://bit.ly/2E6ZBah

Bentham Science Free Trial in The University’s Library of The Jan Kochanowski University in Kielce| Free Trial ends on April 30, 2019

 

The library commenced its functioning in 1969 when The Teachers’ College was created. The collection of books and manuscripts, the place of operation as well as employees, were inherited after The Library of Teachers’ Studies (including the collection gathered by then already non-existent The Pedagogical High School, which was the original proprietor of the place mentioned herein-above).

The library has gone beyond an immense transformation during its forty years of existence. Conditions had been changing, the library had been moving places and restructuring. There had been a continual rotation in crew and employers individual task and responsibilities had been altering. Yet, most importantly, the collection had been growing. Besides traditional – paper volumes, there had been appearing new, digital information storage media and huge databases. The library’s collection has been being digitalised henceforth. Therefore, work conditions for the librarians have chanced significantly, as as well as their theoretical and practical backgrounds.

 

Wishing you a very Happy Birthday | Dr. Chad E. Beyer

 

Dr. Chad E. Beyer

Editor in Chief: Technology Transfer and Entrepreneurship

 

Chad E. Beyer
Promentis Pharmaceuticals
Milwaukee, WI
USA

Editor’s Choice Article | Diastasis Recti Abdominis-diagnosis, Risk Factors, Effect on Musculoskeletal Function, Framework for Treatment and Implications for the Pelvic Floor

Author(s): Laura Anne Werner*, Marcy Dayan.

Journal Name: Current Women`s Health Reviews

 

Graphical Abstract:

 

Abstract:

Diastasis Recti Abdominis (DRA) can occur during pregnancy and postpartum. It is defined as an increase of the inter-recti distance (IRD) beyond normal values. The diagnosis of DRA is inconsistent within the literature and varies depending on measurement instrument and activity during measurement (rest versus active curl-up). DRA is characterized by the stretching of linea alba (LA) and contributes to a protrusion of the anterior abdominal wall due to increased laxity in the myofascial system that supports abdominal viscera. DRA has been postulated to affect lumbopelvic support and function due to laxity of the LA and altered angle of muscle insertion, but recent studies have not confirmed this. Risk factors for the development of DRA have been investigated in pregnancy to 12-months postpartum. Read out full article here: http://www.eurekaselect.com/160043/article

Bentham Science Free Trial in The Institute of bioorganic chemistry | Free Trial ends on March 6, 2019

The Institute of bioorganic chemistry

The M.M. Shemyakin–Yu.A. Ovchinnikov Institute  of Bioorganic Chemistry of the Russian Academy of Sciences came into existence initially under the name of the Institute for Chemistry of Natural Compounds by a decree of the Russian academy of sciences Presidium issued in February, 1959. The foundation of the Institute and its further development are inseparably linked with the names of outstanding scientists Professor M.M. Shemyakin and Professor Yu.A. Ovchinnikov.

  

Institute directors 

Today the Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry is the main center of physical-chemical biology and biotechnology in Russian Federation. It’s included in the Department of biological sciences of Russian academy of sciences and performs activities connected with biochemical research of living matter. It researches molecular mechanisms of vital processes and their practical use in medicine and agriculture. Moreover the Institute develops fundamental and applied aspects of biotechnologies.

 

   

Building and laboratories

 

Situated in Moscow on the Mikluho-Maklaya street complex of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry is a unique building for multipurpose fundamental research. The Institute has an up-to-date complex plant for development technologies of production new medicines and preparations for agriculture.

 

Editor’s Choice Article | The Future of Biogas Production in Cameroon: Prospects, Challenges and Opportunities

Author(s): Erasmus Muh*, Fouzi Tabet, Sofiane Amara.

Journal Name: Current Alternative Energy

 

Graphical Abstract:

 

Abstract:

Cameroon is blessed with a vast potential of energy resources. However, their level of valorization is deplorable causing acute energy challenges. Consequently, most Cameroonians, mainly rural dwellers are dependent on traditional biomass and petroleum products for their basic energy needs despite their associated adverse health and the environmental impacts. Thus, there is a need for alternative, affordable and reliable energy sources to meet this energy gap. This study, therefore, reviews and assesses the prospects and sustainability of biogas production in Cameroon. Read out full article here: http://www.eurekaselect.com/165655/article

Editor’s Choice Article | Chemistry and Biology of Secondary Metabolites from Aspergillus Genus

Author(s): Xiaolei Zhang, Zhi Li, Jiangtao Gao*.

Journal Name: The Natural Products Journal

Abstract: Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the genus produces a wide range of structurally diverse secondary metabolites that are of highly considerable interest to both scientific research community and pharmaceutical industry. Genome sequencing results have indicated that chemical diversity of secondary metabolites is much larger in each species than previously thought.

This review summarizes a total of 315 new secondary metabolites of Aspergillus reported from 2015 to 2017 and demonstrates the therapeutical potential of this genus by introducing their unique chemical structures and excellent bioactivities from this genus. Read out full article here: http://www.eurekaselect.com/161751/article

 

Open Access Articles | A Network Integration Method for Deciphering the Types of Metabolic Pathway of Chemicals with Heterogeneous Information

Author(s): Zi-Han Guo, Lei Chen*, Xian Zhao.

Journal Name: Combinatorial Chemistry & High Throughput Screening

 

A metabolic pathway is an important type of biological pathway, which is composed of a series of chemical reactions. It provides essential molecules and energies for living organisms. To date, several metabolic pathways have been uncovered. However, their completeness is still on the way. A number of prediction methods have been built to assign chemicals into certain metabolic pathway, which can further be used to predict novel latent chemicals for a given metabolic pathway. However, they did not make use of chemical properties in a system level to construct prediction models. Read out full article here: http://www.eurekaselect.com/168115