Article by disease on “Polio”
Abstract: The innate immune system provides protection against invading neurotropic viruses. It acts as the first line of defense against invading viruses and plays an elementary role in their pathogenesis. The list of viruses capable of infecting human central nervous system (CNS) is quite long, most important of them are Japanese Encephalitis virus (JEV), rabies virus, West Nile virus (WNV), herpes simplex virus (HSV), St. Louis encephalitis virus (SLEV), La Crosse virus, tick borne encephalitis virus (TEBE) and polio virus. Germ line pattern recognition receptors (PRRs) such as Toll like receptors (TLRs), nucleotide binding oligomerization domain (NOD) – like receptors (NLRs), retinoic acid-inducible gene I (RIG-I) -like helicases or RIG-I-like receptors (RLRs) and cytosolic DNA sensors recognize the pathogen associated molecular patterns (PAMPs) and initiate an immune response against invading pathogen. Although PRRs were originally characterized in peripheral immune cells but accumulating evidence also suggest their crucial roles in CNS to combat against neurotropic viruses. In this review, we will highlight the recent developments in our understating of the mechanisms by which PRRs in resident brain cells provide protection against invading neurotropic viruses.
Bentham Science stands with Polio patients on the World Polio Day, 24th October 2016. Find the latest research papers published in our journals that focus on Polio and its treatments. The most significant one is:
Minerals are an essential part of our diet. Among the long list of minerals, Iodine is a key ingredient that the human body requires. Deficiency of Iodine can cause serious health issues. According to The World Health Organization (WHO) over 2 billion people all over the world may have iodine deficiency and up to 50 million of them are facing serious symptoms like brain damage.
In the human body, thyroid is a gland that produces sufficient hormones to meet the body’s needs. For the development of hormones in thyroid gland our body needs sufficient amount of iodine. The deficiency of it can cause the gland to work harder than its capacity. This can result in the enlargement of thyroid gland; this condition is called goiter.
The best way to prevent iodine deficiency is to ensure that you take right amount of food which has the mineral in abundance, such as, bread, eggs, dairy products, iodized salt and some vegetables.
Bentham Science Publishers stands with people suffering with Iodine deficiency disorders. Find the latest research articles published on Iodine Deficiency.
Today, on the 21st of October 2016, we raise awareness about the disorders caused by the Iodine Deficiency. Bentham Science Publishers has various research journals dedicated to Iodine and other Deficiencies. The most significant one is;