eBooks Catalog – Physics & Astronomy

7-23-2014 11-33-22 AM

http://benthamscience.com/catalog/catalog-files/catalog-physics-astronomy.pdf

Brand New eBook Podcast!!

7-23-2014 8-07-25 AM

EBook: “Gravity-Superconductors Interactions: Theory and Experiment”

Author: Giovanni Modanese

YouTube link: https://www.youtube.com/watch?v=sH1p6Cn7ft4&feature=youtu.be

Bentham Science Publishers free 3 months trial is active in the following university:

 University:  DAYANAND MEDICAL COLLEGE & HOSPITAL 

About the university:

Dayanand Medical College & Hospital (DMCH) Ludhiana, Punjab, India is a 1326 bedded (Inclusive 800 teaching beds) tertiary care teaching hospital in North India. The institution has an imposing complex of modern buildings and is equipped with all kinds of modern facilities for providing excellent care to the patients and training to the undergraduate and postgraduate students. All the clinical departments, along with the diagnostic laboratories provide round-the-clock service at the campus.

 http://www.dmch.edu

Recent Issues of the Following Journals have been Published!

The Natural Products Journal, 4 Issue 1

7-22-2014 8-25-42 AM

Editor-in-Chief:

Francesco Epifano

Università “G. D’Annunzio”

Chieti-Pescara, Chieti Scalo (CH)
Italy

Aims & Scope

The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products.

The Natural Products Journal publishes original research articles, reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.

www.eurekaselect.com

 Abstracted & Indexed in:

Chemical Abstracts, J-Gate, PubsHub.

http://www.eurekaselect.com/123357/issue/1

For details, visit: http://benthamscience.com/journal/index.php?journalID=npj

Clinical Immunology, Endocrine & Metabolic Drugs, 1 Issue 1

7-22-2014 8-27-34 AM

Editor-in-Chief:

Emilio Jirillo

Professor of Immunology, University of Bari
Bari
Italy 

Aims & Scope

Clinical Immunology, Endocrine & Metabolic Drugspublishes original research, expert reviews, drug clinical trials and thematic issues in all core areas of translational and clinical immunology, endocrine & metabolic drug research.

The journal publishes pre-clinical and clinical studies on the development of new immunology, endocrine & metabolic agents. Clinical studies of new reported immunology, endocrine & metabolic drugs include Phase 1 – IV clinical trial studies, their designs, research methodologies, and analyses. The journal is essential reading to clinicians, toxicologists, medicinal chemists, and pharmacologists.

http://www.eurekaselect.com/123473/issue/1

For more details, visit: http://benthamscience.com/journal/index.php?journalID=ciemd

CNS & Neurological Disorders – Drug Targets , 13 Issue 5

Editor-in-Chief:

Stephen D. Skaper

Department of Pharmaceutical and Pharmacological Sciences
University of Padova
Padova
Italy

Aims & Scope

CNS & Neurological Disorders – Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes.

CNS & Neurological Disorders – Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of CNS & neurological drug targets. The journal also accepts for publication original research articles, letters, reviews and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

www.eurekaselect.com

Abstracted & Indexed in:

Science Citation Index Expanded, MEDLINE, PubMed, BIOSIS, BIOSIS Previews, BIOSIS Reviews Reports and Meetings, Chemical Abstracts, EMBASE/Excerpta Medica, PsycINFO, Current Contents®/Clinical Medicine, Journal Citation Reports/Science Edition, Scopus, Neuroscience Citation Index®, MediaFinder®-Standard Periodical Directory, Genamics JournalSeek, PubsHub, J-Gate.

http://www.eurekaselect.com/123446/issue/5

For more information, visit: http://benthamscience.com/journal/index.php?journalID=cnsnddt

Current Organic Chemistry, 18 Issue 10

7-22-2014 8-37-11 AM

Editor-in-Chief:

Atta-ur-Rahman

FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: coc@benthamscience.org 

Aims & Scope

Current Organic Chemistry aims to provide in-depth reviews on the current progress in the fields of asymmetric synthesis, organo-metallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry and analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic chemistry.

www.eurekaselect.com

Abstracted & Indexed in:

Science Citation Index, Science Citation Index Expanded, Journal Citation Reports/Science Edition, Current Contents®(Physical, Chemical and Earth Sciences), Chemistry Citation Index®, Chemical Abstracts, Science Citation Index Expanded, Scopus, PubsHub, Genamics JournalSeek,Research Alert, SciSearch, Engineering Village/Chimica, MediaFinder®-Standard Periodical Directory, J-Gate.

http://www.eurekaselect.com/123455/issue/10

For details, visit: http://benthamscience.com/journal/index.php?journalID=coc

SMI Event!!

Clinical Trials in CNS

P-123-200x200

11-12 November 2014

 SMi is proud to announce its 13th annual Clinical Trials in CNS Conference. With an ever increasing average life expectancy, neurodegenerative diseases are becoming more prevalent in society. With this comes the need for new and improved therapies for treating neurodegenerative conditions. From Alzheimer’s to Parkinson’s disease, the target and mechanism by which a disease manifests itself presents unique challenges in how to approach such treatments not to mention ethical and legal issues behind treatment and trial design.

This conference will give delegates the opportunity to gain additional insights into the best practices in clinical trials, as well as address the challenges in CNS research and by looking at the latest pre-clinical and clinical studies.

This is an opportunity not to be missed, as we delve into the complex and exciting world of Central Nervous System discovery, allowing delegates to learn, explore and debate the key areas of CNS, its preclinical discovery and its clinical trials.

 For details, visit: http://www.smi-online.co.uk/2014clinicaltrialscns7.asp

Brand New eBook Podcast!!

Ebook: Introduction to Computer Data Representation

Author: Peter Fenwick

https://www.youtube.com/watch?v=9Y0tOjbOWmE&list=PLgqAw3jxjphlxftyRhiuTUbAfqXM3sgmB&index=18

 For further information, please visit: http://bit.ly/1nhA1SA

Happy Birthday!!

7-21-2014 8-30-59 AM

Recent Issues of the following journals have been published:

Adolescent Psychiatry, 4 Issue 2

 Aims & Scope

Adolescent Psychiatry publishes reports of original research, critical reviews of topics relevant to practitioners, clinical observations with analysis and discussion, analysis of philosophical, ethical or social aspects of the fields of psychiatry and mental health, case reports with discussions, letters, and position papers.

Adolescent Psychiatry, a peer-reviewed journal, and the official journal of the American Society for Adolescent Psychiatry, aims to provide mental health professionals who work with adolescents with current information relevant to the diagnosis and treatment of psychiatric disorders in adolescence.

www.eurekaselect.com

 Abstracted & Indexed in:

PsycINFO, PubsHub, J-Gate.

http://www.eurekaselect.com/123231/issue/2

For more details, visit: http://benthamscience.com/journal/index.php?journalID=aps

 

Current Proteomics, 11 Issue 1

 Aims & Scope

Research in the emerging field of proteomics is growing at an extremely rapid rate. The principal aim of Current Proteomics is to publish well-timed review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry.

Current Proteomics publishes review articles in all aspects of the fast-expanding field of proteomics. All areas of proteomics are covered together with the methodology, softwares, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to:

  • Protein separation and characterization techniques
  • 2-D gel electrophoresis and image analysis
  • Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching
  • Determination of co-translational and post- translational modification of proteins
  • Protein/peptide microarrays
  • Biomolecular interaction analysis
  • Analysis of protein complexes
  • Yeast two-hybrid projects
  • Protein-protein interaction (protein interactome) pathways and cell signaling networks
  • Systems biology
  • Proteome informatics (bioinformatics)
  • Knowledge integration and management tools
  • High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography)
  • High-throughput computational methods for protein 3-D structure as well as function determination
  • Robotics, nanotechnology, and microfluidics

In addition to in-depth reviews, articles highlighting recent proteomics papers of special interest as well as book reviews are published. Mini-reviews and perspective articles are also published. In view of the importance of specific technology and software developed for advancement of proteomics research, a separate section is devoted to product and technology reports. Proceedings of proteomics meetings with selected review articles on topics presented are also published.

www.eurekaselect.com

 Abstracted & Indexed in:

Chemical Abstracts, BIOSIS Previews, BIOSIS Reviews Report and Meetings, Scopus, BIOBASE, EMBiology, Science Citation Index Expanded (SciSearch), Index to Scientific Reviews, Biotechnology Citation Index, Journal Citation Reports/Science Edition, Genamics JournalSeek, Mediafinder- Standard Periodical Directory, PubsHub, J-Gate.

http://www.eurekaselect.com/123238/issue/1

For details, visit: http://benthamscience.com/journal/index.php?journalID=cp

Chinese Authors have made substantial contributions to Bentham Science Journal Current Drug Targets:

Journal Name: Current Drug Targets

7-18-2014 9-12-03 AM

Article Title:

Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis

Author(s): Nian-Hua Ding, Jian Jian Li and Lun-Quan Sun

Abstract:

Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer patients that presents as a progressive pulmonary injury combined with chronic inflammation and exaggerated organ repair. RILF is a major barrier to improving the cure rate and well-being of lung cancer patients because it limits the radiation dose that is required to effectively kill tumor cells and diminishes normal lung function. Although the exact mechanism is unclear, accumulating evidence suggests that various cells, cytokines and regulatory molecules are involved in the tissue reorganization and immune response modulation that occur in RILF. In this review, we will summarize the general symptoms, diagnostics, and current understanding of the cells and molecular factors that are linked to the signaling networks implicated in RILF. Potential approaches for the treatment of RILF will also be discussed. Elucidating the key molecular mediators that initiate and control the extent of RILF in response to therapeutic radiation may reveal additional targets for RILF treatment to significantly improve the efficacy of radiotherapy for lung cancer patients.

For more details, visit: http://benthamscience.com/journal/abstracts.php?journalID=cdt&articleID=113785

Article Title: Novel Targeted Therapies to Overcome Trastuzumab Resistance in HER2- Overexpressing Metastatic Breast Cancer

Author(s): Yuan Huang, Peifen Fu and Weimin Fan

Abstract:

Overexpression of the human epidermal growth factor receptor 2 (HER2) is identified in approximately 25- 30% of breast cancers and indicates a poor prognosis. Trastuzumab, the anti-HER2 monoclonal antibody (mAb), has shown significant clinical effects selectively in HER2-overexpressing metastatic breast cancer (MBC) with improved overall survival and reduced recurrent risk. However, there is an urgent need to develop new strategies to overcome innate and acquired trastuzumab resistance, which has increasingly occurred. Recently, an increased understanding of mechanisms of trastuzumab resistance significantly promotes the development of novel targeted therapies for trastuzumabrefractory disease. It is believed that aberrant activations of several signaling pathways involving the human epidermal growth factor receptor (EGFR/HER) family, phosphoinositide 3 kinase/Akt (PI3K/Akt) pathway, and vascular endothelial growth factor (VEGF) family, contribute to the development of trastuzumab resistance. Novel agents that target these relevant signal pathways provide some potential solutions, such as tyrosine kinase inhibitors (TKIs) and mAbs. HER2 is also recognized as an immunotherapeutic target. The failure to induce immune-mediated antitumor response is another important reason for trastuzumab resistance. Strategies to boost T cell-mediated immune responses specific to HER2 including HER2 vaccines and bispecific antibodies (bsAbs) could be developed as a promising way to prevent relapse or combat trastuzumab resistance. In this review, the emerging data from preclinical and clinical studies related to these novel therapies will be discussed.

Article Title: Improving the Embryo Implantation Via Novel Molecular Targets

Author(s): Jingjie Li, Xiaoyan Liang and Zijiang Chen

Abstract:

With the development of modern assisted reproductive technology(ART), the treatment of infertility and the pregnant outcome by ART have been significantly improved. However, implantation failure, particularly the unexplained repeated implantation failure (RIF), is still the unsolved and principal problem to affect the outcome of ART. The completed embryo, the receptive uterus and a series of precisely controlled molecular events between the blastocyst and endometrium are all indispensable for the success of implantation. Thus, deep insight into the molecular mechanisms that impact the endometrial receptivity and embryo implantation is an effective way to improve the implantation rate. Here the novel molecular targets and biomarkers have been reviewed that are reported and proved during more recent years in the aspects of ion channels, aquaporins, long noncoding RNAs and microRNAs, kruppel like factors, metabolism related molecules and the endogenous retroviruses. Evaluation of implantation markers may help clinicians to predict pregnancy outcome and detect occult implantation deficiency. Moreover, these novel molecular targets are expected to apply to the clinical practice from bench to bedside and improve the implantation efficiency in ART and natural conception.

Article Title:

Recent Developments in the Discovery of Novel Antipsychotic Agents Modualating Dopamine and Serotonin Receptors

Author(s): Xin Li and Shutao Ma

Abstract:

Currently, schizophrenia, as a serious psychiatric disorder, continues affecting the quality of life in the psychotics. This disease is often debilitating and chronic, showing broad symptoms at one end by hallucinations, delusions, thought disorder and the other end by affective flattening, catatonia, social isolation. In order to combat this disease, many antipsychotic drugs have been developed and introduced into clinical practice in the past half century. However, only a small minority of them can treat effectively schizophrenia without side effects. In view of this situation, high attention has been given to the exploration of desired antipsychotic agents influential especially through the modulation of dopamine and serotonin receptors with substantial strides made in recent years, leading to the discovery of many novel chemical entities with intriguing profiles. In this review, we summarize novel structural antipsychotics in development and discuss the future direction of ideal antipsychotic drug candiates. In particular, the promising atypical antipsychotic profiles of new molecules and the inspirations for their design are highlighted.

BSP patent Journal: Recent Patents on Nanomedicine

Recent Patents on Nanomedicine

Editor-in-Chief:

Victor Manuel Castano Meneses

Center of Applied Physics and Advanced Technology

National Autonomous University of Mexico
Juriquilla Campus
Queretaro
México

Aims & Scope

Recent Patents on Nanomedicine publishes reviews and research articles, drug clinical trial studies and guest edited thematic issues. A selection of important and relevant recent patents is also included in the journal. The journal is essential reading for all academic, industrial and clinical researchers who wish to be kept informed about important patent breakthroughs in nanomedicine.

Abstracted & Indexed in:

Chemical Abstracts, J-Gate, PubsHub.

For details, visit: http://benthamscience.com/journal/index.php?journalID=rpnanom