This is the third volume of the Patent eBook Series. This eBook comprises updated reviews on topics relevant to modern cancer research published in the journal Recent Patents on Anti-Cancer Drug Discovery. Specifically, regulation of tumor cells by TRAIL receptors, development of anti-cancer drugs & immunomodulatory drugs, molecular studies of adrenocortical cancer, role of inhibitors of inosine monophosphate dehydrogenase in cancer, recent updates in glioblastoma stem cells, latest approaches for cancer gene therapy and metabolic therapy for cancer were carefully reviewed and updated. In addition, the role of pH regulation and application of hyperthermia, thiosemicarbazone derivatives, tamoxifen-based therapies for cancer treatment andproteome-based complex therapy of tumors, calcium signaling and angiogenesis, antineoplastic role of GHRH antagonists and therapeutic applications in human tumors and clinical oncology have been extensively discussed in the light of recent innovations.
I believe that this volume is unique with the following distinctive features. (i) It is highly relevant to clinical treatment of patients with various cancers and the impact of this book should be very broad and significant. (ii) This is a topic, of extreme and timely interest in the field. (iii) This volume will have a general Interest. The comprehensive range of themes covered in this third volume will be of benefit to clinicians, scientists and R&D experts looking for new targets for the prevention of cancer and discovery of drugs for the treatment of different cancer types. The topics covered in this third volume will also be valuable for those interested in scientists interested in methods for the prevention of cancer as well its management.
Q. Ping Dou, Ph.D.
Barbara Ann Karmanos Cancer Institute
Departments of Oncology, Pharmacology and Pathology