Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Articles from the journal Anti-Cancer Agents in Medicinal Chemistry, 15 Issue 3

Article: Anti-Cancer Agent-Induced Nephrotoxicity

Author(s): Hirotaka Fukasawa, Ryuichi Furuya, Hideo Yasuda, Tatsuo Yamamoto, Akira Hishida and Masatoshi Kitagawa.

Affiliation: Renal Division, Department of Internal Medicine, Iwata City Hospital, 512-3 Ohkubo, Iwata, Shizuoka 438-8550 Japan.

Article: Recent Developments on Thiourea Based Anticancer Chemotherapeutics

Author(s): Vikas Kumar and Swapandeep Singh Chimni

Affiliation: Department of Chemistry,U.G.C. Center of Advance Studies in Chemistry, Guru Nanak Dev University, Amritsar-143005, India

Article: EGFRIndb: Epidermal Growth Factor Receptor Inhibitor

Author(s): Inderjit S. Yadav, Harinder Singh, Mohd. Imran Khan, Ashok Chaudhury, G.P.S. Raghava and Subhash M. Agarwal

Affiliation: Bioinformatics Division, Institute of Cytology and Preventive Oncology, I-7, Sector-39, Noida- 201301, India.

Article: Activation of Integrin β1 Mediates the Increased Malignant Potential of Ovarian Cancer Cells Exerted by Inflammatory Cytokines

Author(s): Zongyuan Yang, Xiaoshui Zhou, Yi Liu, Cheng Gong, Xiao Wei, Taoran Zhang, Ding Ma and Qinglei Gao.

Affiliation: Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Anv. Wuhan, Hubei 430030, China.

 

Article: Chalcone-Coumarin Derivatives as Potential Anti-Cancer Drugs: An in vitro and in vivo Investigation

Author(s): Vincent Jamier, Wioleta Marut, Sergio Valente, Christiane Chereau, Sandrine Chouzenoux, Carole Nicco, Herve Lemarechal, Bernard Weill, Gilbert Kirsch, Claus Jacob and Frederic.

Affiliation: Laboratoire d’Immunologie, 24 rue du faubourg St Jacques 75679 Paris cedex 14, France.

Article: Sesamol Ameliorates Cyclophosphamide-Induced Hepatotoxicity by Modulating Oxidative

Stress and Inflammatory Mediators

Author(s): S. Jnaneshwari, M. Hemshekhar, R.M. Thushara, M. Shanmuga Sundaram, M. Sebastin Santhosh, K. Sunitha, R.L. Shankar, K. Kemparaju and K.S. Girish.

Affiliation: Department of studies and Research in Biochemistry, University of Mysore, Mysore-06 and Tumkur University, Tumkur, Karnataka, India.

Article: Three Amino Acid Derivatives of Valproic Acid: Design, Synthesis, Theoretical and

Experimental Evaluation as Anticancer Agents

Author(s): Gabriela R. Luna-Palencia, Federico Martinez-Ramos, Ismael Vasquez-Moctezuma, Manuel Jonathan Fragoso-Vazquez, Jessica Elena Mendieta-Wejebe, Itzia I. Padilla-Martínez, Yudibeth Sixto-Lopez, David Mendez-Luna, Jose Trujillo-Ferrara, Marco A. Meraz-Rios, Yadira Fonseca-Sabater and Jose Correa-Basurto.

Affiliation: Molecular Modeling and Drug Design Laboratory, Biophysics and Biocatalysis Lab, Biochemistry Lab, Seccion de Estudios de Posgrado e Investigacion y Departamento de Bioquimica, Escuela Superior de Medicina, Instituto Politecnico Nacional, Plan de San Luis y Diaz Miron, Distrito Federal 11340, Mexico.

Article: Synthesis and Biological Evaluation of 3-Substituted-4-(4-methylthio phenyl)-1H- Pyrrole Derivatives as Potential Anticancer Agents.

Author(s): Lan Lan, Weixi Qin, Xiaoping Zhan, Zenglu Liu and Zhenmin Mao

Affiliation: School of Pharmacy, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai 200240, China.

 

Article: Anticancer Activity of New Compounds Using Benzimidazole as a Scaffold.

Author(s): Mohd Rashid, Asif Husain, Mohammad Shaharyar and Mohd

Affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.

Article: Modeling Study of Phenylsulfonylfuroxan Derivatives as P-gp Inhibitors: A Combined

Approach of CoMFA, CoMSIA and HQSAR

Author(s): Changdev G. Gadhe, Anand Balupuri, Pavithra K. Balasubramanian and Seung Joo

Affiliation: College of Medicine, Chosun University, 375 Seosuk-dong, Dong-gu Gwangju 501-759, Republic of Korea.

Article: Trifluoroibuprofen Inhibits α-Methylacyl Coenzyme A Racemase (AMACR/P504S),

Reduces Cancer Cell Proliferation and Inhibits in vivo Tumor Growth in Aggressive Prostate Cancer Models

Author(s): Yoshiko Kaku, Ayako Tsuchiya, Takeshi Kanno and Tomoyuki

Affiliation: Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.

Article: Toxic effects of Aflatoxin B1 on embryonic development of zebrafish (Danio rerio): Potential activity of Piceatannol encapsulated Chitosan/poly (lactic acid) nanoparticles.

Author(s): Claudio Festuccia, Giovanni Luca Gravina, Andrea Mancini, Paola Muzi, Ernesto Di Cesare, Ralph Kirk, Matthew Smith, Shaun Hughes, Robert Gibson, Lu-Yun Lian, Enrico Ricevuto and Andrew J. Carnell.

Affiliation: Dipartimento di Medicina Sperimentale, Radiobiology Laboratory, Universita dell’Aquila, Via Vetoio, Coppito 2, 67100 L’Aquila, Italia.

Article: Hypersensitivity to Aurora Kinase Inhibitors in Cells Resistant against Platinum-

Containing Anticancer Agents

Author(s): Masaki Akiyama, Hiroto Izumi, Ke-Yong Wang, Takahiro Yamaguchi, Akihiro Kuma, Noriaki Kitamura, Yoshikazu Harada, Ryoichi Oya, Koji Yamaguchi, Yoshiko Iwai and Kimitoshi.

Affiliation: President Laboratory, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

Article: ent-Kaurane Diterpenoids from Croton tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK4.

Author(s): Phuong Thien Thuong, Nguyen Minh Khoi, Saho Ohta, Shinichiro Shiota, Hironori Kanta, Kenji Takeuchi and Fumiaki Ito.

Affiliation: Institute of Health Sciences, Sunstar Inc., Takatsuki, Osaka 569-1195, Japan.

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