Recently Published Issues in the Journals of Bentham Science

Recent Patents on CNS Drug Discovery, Volume 10 Issue 1

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Current Alzheimer Research, Volume 12 Issue 7

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Medicinal Chemistry, Volume 11 Issue 6

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Bentham Science High Impact Journals

Pharmaceutical Nanotechnology, 3 Issue 1

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Current Vascular Pharmacology, 13 Issue 4

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Current Clinical Pharmacology, 10 Issue 2

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Current Bioinformatics, 10 Issue 3

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Current Pharmaceutical Design, 21 Issue 23

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CNS & Neurological Disorders – Drug Targets, 14 Issue 7

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Combinatorial Chemistry & High Throughput Screening, 18 Issue 5

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Editor’s Choice Article from the Journal Current Vascular Pharmacology

Current Vascular Pharmacology, 13(4): 423-432



Clinical Zheng-hou Pharmacology: the Missing Link between Pharmacogenomics and Personalized Medicine?

Author(s): Ya-Nan Yu, Jun Liu, Lei Zhang, Zhong Wang, Dayue Darrel Duan and Yong-Yan Wang

Affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, 18 Baixincang, Dongzhimennen, Beijing 100700, China.

Abstract: In Chinese medicine, Zheng-hou, instead of disease, is used to define complex medical problems in clinical practice. In the postgenomics era, it becomes particularly compelling to review the application of Zheng-hou in characterizing complex clinical problems independent of disease or syndrome. While disease or syndrome describes a pathological phenotype or phenotypes, Zheng-hou spells the pathological phenome. Clinical Zheng-hou pharmacology (CZP) is an emerging clinical discipline that aims to leverage breakthroughs in the genome-wide solutions for complex medical problems through a combination of the current “omics” technology and the knowledge of Chinese medicine. The concept of CZP suggests that systematic and standard studies of multiple phenotypes will be important because of the collaborative cross between diversified external and internal factors at different levels both in vitro and in vivo. In this paper, we discuss the novel phenomic approaches to the understanding of Zheng-hou and the link of pharmacogenomics to personalized medicine through CZP, or pharmacophenomics. CZP enables ever-finer mapping of Zheng-hou and detection of dynamic variations in most current omics platforms. Although major challenges still remain in identifying and effectively investigating the diversity of Zheng-hou, CZP is expected to pave new paths to the systemic understanding of medical problems. While still at early stages in the clinical phenome domain, there remains great promise that CZP can help us realize the application of personalized medicine and contribute to rational holistic diagnosis and treatment.

Contributor’s Comments


Contributed Article: A Model to Improve Analysis of CNTFET Logic Gates in Verilog-A – Part II: Dynamic Analysis

Recently Published Issue of the Journal Current Bionanotechnology

Current Bionanotechnology is an international, peer-reviewed journal for bionanoscience and technology. The journal publishes short communications, original research articles, mini-reviews and special issues in all fields of biology, chemistry, physics, engineering, materials science and medicine dealing with biological materials at the nanoscale. The scope covers research which combines biological principles with physical and chemical procedures to generate nano-sized building blocks with specific functions and new properties. Also covered are the design and development of biologically-based procedures, the implementation of biological components and systems, the design of biocompatible objects and systems and the use of nanotechnology to support biotechnological processes. Emphasis is on bottom-up approaches for the design and development of novel nanomaterials.

Following are the articles from the journal Current Bionanotechnology, Volume 1 Issue 1:

Article: The Methods of Nanoparticle Synthesis Using Bacteria as Biological Nanofactories, their Mechanisms and Major Applications

Author(s): S. Ghashghaei and G. Emtiazi


Article: Spider Silk and Bioinspired Silk on Wettability

Author(s): Lin Zhao and Yongmei Zheng


Article: Voltammetric and Impidimetric Detection of Anticancer Drug Mitomycin C and DNA Interaction by Using Carbon Nanotubes Modified Electrodes

Author(s): Ece Eksin, Hakan Karadeniz and Arzum Erdem


Article: Studies on Biocide Encapsulated Zeolite-epoxy Nano Hybrid Coatings on Mild Steel

Author(s): Palanivelu Saravanan, Sridhar Aparna, Srinivasan Ananda Kumar and Dhanapal Duraibabu


Article: About Mechanism of Gas Transport Function and Side Reactions of Perfluorocarbon Nano-dispersions

Author(s): I.N. Kuznetsova


Article: Smart Biodecorated Hybrid Nanoparticles

Author(s): Ignác Capek


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Major Article Contributions by our Indian authors in Bentham Science Publishers Journal, Anti-Cancer Agents n Medicinal Chemistry

anti-canceragentsJournal Name: Anti-Cancer Agents in Medicinal Chemistry

Article Title: Platinum Compounds: A Hope for Future Cancer Chemotherapy

Author(s): Imran Ali, Waseem A. Wani, Kishwar Saleem and Ashanul Haque


The discovery of cis-platin and its second and third generation analogues created a hope in cancer chemotherapy. Cis-platin and its second generation analogue carboplatin have been used for the treatment of some cancers from a long time. The third generation analogues have superior anti-cancer profiles for curing a few cancers. Unfortunately, certain side effects such as renal impairment, neurotoxicity and ototoxicity etc. are associated with these drugs. But, combination therapy makes these analogues more effective with fewer side effects. In addition, the results of some ongoing clinical trials will make the safety profile clear in near future. The present article describes the current status of cis-platin and its analogues in cancer chemotherapy. In addition, special emphasis has been made on cis-platin discovery, development of second (carboplatin, oxaliplatin, nedaplatin) and third (lobaplatin, heptalatin) generation analogues, comparison of their chemotherapies, mechanism of action, therapeutic status, recent developments and chronology. Moreover, attempts have been made to describe the future perspectives of these drugs in the cancer treatment.

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Open Access Pluss Explained

Through Open Access Plus, authors of accepted papers are given the option of paying an open access publication charge to make their paper freely available online immediately via the journal website, meaning that readers will not need a journal subscription to view open access content. If an author does not choose to pay the open access publication charge, their article will be published with the standard subscription-based access at no cost. Open access plus articles will be clearly indicated on the journal’s online contents access pluss at bsp4
Bentham Science offers 40% discount on open access fees to their Editors, Board members and those authors who have contributed more than two articles in Bentham Science publications.
In case you are interested in publishing your article as open access, please email to at your earliest.
When you choose Open Access plus, your and your readers’ benefits are
  • Your article is freely available online.
  • Easy compliance with open access mandates.
  • Final version can be re-used and immediately deposited in any repository.
  • Automatic export triggered to PubMed Central/Europe PubMed Central (PMC).








Podcast: Ride or Die; Therapeutic Interventions for Retaliatory Violence Among Youth

Violence among youth continues to be a serious public health concern across the nation. Researchers have increasingly argued that effective violence preventions efforts and practice must consider the lived experience of youth. Retaliatory violence (i.e., violence in response to a perceived attack or threat) is a major concern and risk issue for young people, and has been increasingly linked to lethal violence. Primary care and mental health practitioners can play a vital role in helping young people who struggle with retaliatory violence to understand the emotions and decisions associated with these situations. However, there is limited research advising clinicians on how to help youth negotiate these issues in treatment.

Watch more podcasts on Bentham Science YouTube Channel

Recently Published Issue of the Journal Current Neurovascular Research

Current Neurovascular Research provides a cross platform for the publication of scientifically rigorous research that addresses disease mechanisms of both neuronal and vascular origins in neuroscience. The journal serves as an international forum publishing novel and original work as well as timely neuroscience research reviews in the disciplines of cell developmental disorders, plasticity, and degeneration that bridge the gap between basic science research and clinical discovery. Current Neurovascular Research emphasizes the elucidation of disease mechanisms, both cellular and molecular, which can impact the development of unique therapeutic strategies for neuronal and vascular disorders.

Following are the articles from the journal Current Neurovascular Research, 12 Issue 3:

: MicroRNAs and Stem Cells to the Rescue

Author(s): Kenneth Maiese


Article: Differential Regulation of microRNAs in Patients with Ischemic Stroke

Author(s): Sheng-Hua Li, Sheng-You Su and Jing-Li Liu


Article: Combination of Local Transplantation of In Vitro Bone-marrow Stromal Cells and Pulsed Electromagnetic Fields Accelerate Functional Recovery of Transected Sciatic Nerve Regeneration: A Novel Approach in Transected Nerve Repair

Author(s): Rahim Mohammadi and Sirvan Mahmoodzadeh


Article: Radix Angelica Sinensis Promotes Synaptic Plasticity During Cognitive Recovery in Chronically Stressed Rats

Author(s): Min Deng, Huimin Sun, Jun Shen, Yuanteng Fan, Lei Zhang and Junjian Zhang


Article: Neuroprotective Effects of Agomelatine and Vinpocetine Against Chronic Cerebral Hypoperfusion Induced Vascular Dementia

Author(s): Surbhi Gupta, Prabhat Singh, Brij Mohan Sharma and Bhupesh Sharma


Article: Interleukin-1β Receptor Antagonism Prevents Cognitive Impairment Following Experimental Bacterial Meningitis

Author(s): Tatiana Barichello, Jaqueline S. Generoso, Lutiana R. Simoes, Vladislav G. Sharin, Renan A. Ceretta, Diogo Dominguini, Clarissa M. Comim, Marcia C. Vilela, Antonio Lucio Teixeira and Joao Quevedo


Article: Rufinamide Improves Functional and Behavioral Deficits via Blockade of Tetrodotoxin-Resistant Sodium Channels in Diabetic Neuropathy

Author(s): Shivsharan B. Kharatmal, Jitendra N. Singh and Shyam S. Sharma


Article: Outcome Prediction after Non-aneurysmal Non-traumatic Subarachnoid Hemorrhage

Author(s): Ramazan Jabbarli, Matthias Reinhard, Roland Roelz, Mukesch Shah, Wolf-Dirk Niesen, Klaus Kaier, Christian Taschner, Astrid Weyerbrock and Vera Van Velthoven


Article: Perfusion-diffusion Mismatch Predicts Early Neurological Deterioration in Anterior Circulation Infarction without Thrombolysis

Author(s): Chia-Yu Hsu, Chun-Yu Cheng, Yuan-Hsiung Tsai, Jiann-Der Lee, Jen-Tsung Yang, Hsu-Huei Weng, Leng-Chieh Lin, Ying-Chih Huang, Meng Lee, Ming-Hsueh Lee, Chih-Ying Wu, Ya-Hui Lin, Huan-Lin Hsu, Hsin-Ta Yang, Yi-Ting Pan and Yen-Chu Huang


Article: Acute and Chronic Treatments with Quetiapine Increase Mitochondrial Respiratory Chain Complex Activity in the Rat Brain

Author(s): Zuleide M. Ignacio, Gislaine Z. Reus, Helena M. Abelaira, Stephanie E. Titus, Anelise S. Carlessi, Jaine R. da Luz, Beatriz I. Matias, Livia Bruchchen, Milena Carvalho-Silva, Lara M. Gomes, Joyce Rebelo, Emilio L. Streck and Joao Quevedo


Article: VEGF Signaling Regulates Cofilin and the Arp2/3-complex within the Axonal Growth Cone

Author(s): Matthias Dumpich, Hans Georg Mannherz and Carsten Theiss


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Highlighted Article of the Journal; Current Drug Targets


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Free Online Trial is active in the following Italian Universities:


University of Eastern Piedmont

The University of Eastern Piedmont Amedeo Avogadro (Italian: Università degli Studi del Piemonte Orientale “Amedeo Avogadro”, UNIPMN or UPO) is a university located in Alessandria, Novara and Vercelli, Italy. It was founded in 1998 and is organized in 7 faculties.

Universita’ degli Studi di Napoli Federico II

The University of Naples Federico II (Italian: Università degli Studi di Napoli Federico II) is a university located in Naples, Italy. It was founded in 1224 and is organized into 13 faculties. It is the world’s oldest state university and one of the oldest academic institutions in continuous operation.

Federico II is the third University in Italy by number of students enrolled, despite its huge dimensions it still represents one of the best Universities in Italy being an excellence in particular for research; in 2015 it was ranked among the first 100 universities in the world by citations per paper. The university is named after its founder Frederick II.

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