New Issue ::: Current Drug Targets

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication mini- & full-length review articles and drug clinical trial studies.As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Articles from the journal Current Drug Targets, 16 issue 9

Article: Novel Approaches for Potential Therapy of Cystic Fibrosis

Author(s): Victoria Sawczak, Paulina Getsy, Aliya Zaidi, Fei Sun, Khalequz Zaman and Benjamin Gaston


 

Article: Targeting the Root Cause of Cystic Fibrosis

Author(s):  Laura Trescott, Joshua Holcomb, Nicholas Spellmon, Cathy Mcleod, Leala Aljehane, Fei Sun, Chunying Li and Zhe Yang


Article: PDZ Structure and Implication in Selective Drug Design against Cystic Fibrosis

Author(s): Joshua Holcomb, Nicholas Spellmon, Laura Trescott, Fei Sun, Chunying Li and Zhe Yang

 

Article: Targeting ENaC as a Molecular Suspect in Cystic Fibrosis

Author(s): Nadine Bangel-Ruland, Katja Tomczak and Wolf-Michael Weber

 

Article: Targeting Molecular Chaperones for the Treatment of Cystic Fibrosis: Is It a Viable Approach?

Author(s):  Ashley Heard, Jake Thompson, Jessica Carver, Michelle Bakey and X. Robert Wang

 

Article: SUMOylation Modulates CFTR Biogenesis: Is the Pathway Druggable?

Author(s): Annette Ahner and Raymond A. Frizzell

 

Article: Epigenetics in Cystic Fibrosis: Epigenetic Targeting of a Genetic Disease

Author(s):  Nualpun Sirinupong and Zhe Yang

 

Article: Bioactive Food Components as Dietary Intervention for Cystic Fibrosis

Author(s): Nualpun Sirinupong and Zhe Yang

 

Article: CFTR Regulation of Aquaporin-Mediated Water Transport: A Target in Male Fertility

Author(s): Marco G. Alves, Rosália Sá, Tito T. Jesus, Mário Sousa and Pedro F. Oliveira

 

Article: Personalized Drug Therapy in Cystic Fibrosis: From Fiction to Reality

Author(s): Fernando Augusto de Lima Marson, Carmen Silvia Bertuzzo and Jose Dirceu Ribeiro –

 

For details, please visit: http://bit.ly/1LzSgJC

 

Articles by Disease ::: Ophthalmology

‘A Promising Future for Peptides in Ophthalmology: Work Effectively and Smartly’

Author(s): Q. Sun and X. Xu

Abstract: Despite progress in pharmacological modalities, treatments for ocular diseases are inconvenient, traumatic, costly and often end in poor final visual results. Peptides, considered as protein fragments, can adequately mimic protein binding and thus are used as therapeutic agents. Chemical modifications and bioengineering techniques are being frequently introduced to improve efficacy and stability of peptides, thereby improving their druggability. Cell-penetrating peptides (CPPs), peptides characterized by penetrating plasma membrane, are famous barrier- passers.

Read the complete article here: http://www.eurekaselect.com/node/127661/article

 

article by disease - ophthamology

 

New Issue ::: Current Molecular Imaging

Current Molecular Imaging publishes peer reviewed expert review articles and special topic issues on all aspects of experimental and clinical research in molecular imaging. Topics include the investigative and practical applications of novel radiopharmaceuticals; standard and complicated imaging methodologies and probes; as well as standard and evolving quantitative approaches

Following are the articles from the journal Current Molecular Imaging, 3 issue 3:

Article: FDG-PET/CT for Systemic Infections

Author(s): Soren Hess, Nick U.M. Jakobsen, Mette B. Brondserud, Eivind A. Segtnan and Soren Schifter

 

Article: Potential Applications of FDG-PET/CT in COPD: A Review of the Literature

Author(s):  Soren Hess and Poul Henning Madsen

 

Article: Feasibility of FDG PET in Inflammatory Bowel Disease

Author(s): Sofie Baek Christlieb, Soren Hess and Poul Flemming Hoilund-Carlsen

 

Article: FDG-PET/CT in Rheumatoid Arthritis: A Review

Author(s): Stine Bjorn Kristensen and Soren Hess

 

Article: FDG-PET in Tuberculosis

Author(s):  Bhagwant Rai Mittal and Kanhaiyalal Agrawal

 

Article: The Role of 18F-FDG-PET/CT in Infectious Endocarditis and Cardiac Device Infection

Author(s): Kate Isabella Rewers, Asbjorn Mathias Scholtens, Anders Thomassen and Soren Hess

 

Article: FDG-PET/CT Imaging of Infected Bones and Prosthetic Joints

Author(s):  Sandip Basu, Thomas C. Kwee and Soren Hess

 

Article: Applications of FDG-PET/CT in Assessment of Vascular Infection and Inflammation

Author(s): Saeid Gholami, Sara Fardin, Sina Houshmand, Susanne H. Hansson, Abass Alavi and Soren Hess

 

Article: Quantitative Analysis of Focal Liver Injury Using the Apparent Diffusion Coefficient in Patients with Biliary Obstruction from Common Bile Duct Stones: A Pilot

Author(s): Shunlin Guo, Junqiang Lei, Yanan Zhai, Ping Chen, Hao Zhang, Jing Zhang, Ryan Lo and Youmin Guo

 

Article: Left Ventricular 2-[18F]-Fluoro-2-Deoxy-D-Glucose Uptake Using Modified Oral Glucose Loading Protocol With Pre-Medicated Niacin On Positron Emission Tomography/Computed Tomography – A Preliminary Study

Author(s): Mohd Nazmi Nordin, Abdul Jalil Nordin, Fathinul Fikri Ahmad Saad and Hairil Rashmizal Abdul Razak

 

For details, please visit: http://bit.ly/1OxJDVh

 

World Obesity Day 26th October

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Latest research article on obesity

 

‘Obstructive Sleep Apnea and Obesity’

Author(s): Shyam Subramanian and Kingman Strohl.

Current Respiratory Medicine Reviews, 4(2): 95-99.

Abstract: Obesity trends continue to rise in alarming proportions worldwide. Obstructive sleep apnea, an increasingly commonly recognized disorder, is characterized by recurrent episodes of upper airway closure during sleep, and obesity is proposed to be its strongest risk factor. Recognition strategies for OSA in obesity are overwhelmed by the sheer prevalence of obstructive sleep apnea, > 80% in those with a BMI > 40. Obesity has direct as well as indirect influences on upper airway mechanics and physiology.

more here: http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/4/issue/2/page/95/

Bentham eBooks by Subject

Bentham Science Publishers has a vast range of eBooks in the subjects listed below. Please click on your subject of interest to find all the available eBooks.








Bentham celebrates the birthday of famous personalities in history!

 

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Article By Disease: Metabolism

‘Repurposed Drugs in Metabolic Disorders’

Author(s): Josef Finsterer and Marlies Frank

Abstract: Drug repurposing (drug repositioning, drug reprofiling, drug retasking) gains increasing importance as the development of new drugs becomes increasingly expensive. Though only a few compounds have been approved for new indications in the field of metabolic disorders, there are a number of substances which have the potential to become reprofiled in a new indication. Generally, reprofiled drugs for metabolic disorders can be classified in three groups. Group A contains those of which both, the original and repurposed indication, concern metabolic disorders. Group B comprises drugs, which were originally approved for non-metabolic disorders but show beneficial effects for metabolic disorders after repurposing..

Download the complete article from here: http://www.eurekaselect.com/node/115624/article


This article is from the journal Current Topics in Medicinal Chemistry

 

Three months free trial for universities/institutes

Bentham Science Publishers offers free trial for 3 months to universities, institutes and libraries around with world. The university below is availing this offer to access Bentham Science journals


North-Western State Medical University – Russia

North-western State Medical University named after I.I.Mechnikov was formed on October the 12-th,  2011, as a result of merger of two oldest educational medical institutions in Russia – Saint-Petersburg Medical Academy of Postgraduate Studies and Saint-Petersburg State Medical Academy n. a. I.I. Mechnikov.

The founder of Mechnikov university is the Ministry of public health of Russian Federation.

The activity of the University is based on cooperation and coordination of educational, clinical and scientific activity. It makes possible to prepare competent specialists, who possess up-to-date knowledge and are able to use it in practice.

4,200 students (~3000 students on budgetary education form and ~1200 on fee-based educational form) are studying at the University, among them are 500 students from foreign countries.

Besides that, at the University are studying over 670 interns and about 1500 clinical residents, 460 Ph.D. candidates do their postgraduate work. Up to 35 000 specialists undergo their short- and long- term postdoctoral training annually.

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Free Online Trial Request form:
http://bit.ly/1BeXpmZ
Email for further assistance:
marketing@benthamscience.org or farah@benthamscience.org
 

World Polio Day – 24th October 2015

banner-Polio Day

Research article on Polio

Current Status of Anti-Picornavirus Therapies
Author(s): Dale L Barnard.

Current Pharmaceutical Design, 12(11): 1379-1390.

Abstract: Picornaviruses are important human pathogens causing severe morbidity and some mortality with the potential to cause worldwide crippling disease. Currently, there are few treatments for many of the viruses in the Picornaviridae, For rhinoviruses, there are no approved treatments, although ruprintrivir looks promising in clinical trials and pyridazinyl oxime ethers may prove useful. Poliovirus treatments are needed to supplement the World Health Organizations polio eradication plan in order to treat infections caused by reversion of the attenuated vaccine virus and to supplement vaccine coverage control in polio endemic areas.

Chinese abstracts ::: Journal ‘Current Medicinal Chemistry’

Current Medicinal Chemistry, Volume 22 – Number 29

Structural Properties of Potential Synthetic Vaccine Adjuvants – TLR Agonists

View Abstract 中文摘要


Endosome Escape Strategies for Improving the Efficacy of Oligonucleotide Delivery Systems 

View Abstract 中文摘要


Novel Drug Therapies for Fertility Preservation in Men Undergoing Chemotherapy: Clinical Relevance of Protector Agents

View Abstract 中文摘要


Current and Future Trends in Early Detection of Pancreatic Cancer: Molecular Targets and PET Probes

 View Abstract 中文摘要


Advances in the Development of Multimodal Imaging Agents for Nuclear/Near-infrared Fluorescence Imaging

  View Abstract中文摘要



– See more at: http://benthamscience.com/journals/current-medicinal-chemistry/volume/22/issue/29/

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