Drug Metabolism Letters publishes letters, original research articles, mini-reviews, thematic issues based on mini-reviews and letters, commentaries, technical notes and drug clinical trial studies on major advances in all areas of drug metabolism and disposition. In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Articles from the journal in Drug Metabolism Letters, 9 Issue 2:

  • Editorial (Thematic Issue: Recent Advances in Developmental Drug Disposition)
  • Biochemical Screening for in utero Drug Exposure
  • Alterations in Hepatic Lipid Metabolism, and their Relation to Dietary Macronutrients in Pediatric Nonalcoholic Fatty Liver Disease
  • Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics
  • The Effects of Obesity on Drug Metabolism in Children
  • Ontogeny of Human Conjugating Enzymes
  • Adverse Drug Events in Children: How Big is the Problem?
  • Downregulation of Hepatic Carbonyl Reductase Type 1 in End-Stage Renal Disease
  • Non-Clinical Disposition and Metabolism of DM1, a Component of Trastuzumab Emtansine (T-DM1), in Sprague Dawley Rats
  • The Detection of Anti-adalimumab Antibodies in a Series of Inflammatory Polyarthritis: three ELISA Methods Compared

For details on the articles, please visit this link: http://bit.ly/1NqxYDw