New Issue ::: Current Drug Abuse Reviews

Current Drug Abuse Reviews aims to publish the highest quality reviews, meta-analyses and drug clinical trial studies on all latest advances on alcohol and drug abuse and addiction.

Book reviews are also published. The Journal will further comprise an agenda listing relevant meetings and conferences that will take place in near future, and advertisement.

Articles from the journal Current Drug Abuse Reviews, Volume 9 Issue 1:

• Laterality of Brain Activation for Risk Factors of Addiction
• Psychosocial Predictors of Relapse Among Patients with Alcohol Problems
• Social Inequality and Substance Use and Problematic Gambling Among Adolescents and Young Adults: A Review of Epidemiological Surveys in Germany
• Pain and Opioid Addiction: A Systematic Review and Evaluation of Pain Measurement in Patients with Opioid Dependence on Methadone Maintenance Treatment
• Combining Stress and Dopamine Based Models of Addiction: Towards a Psycho-Neuro-Endocrinological Theory of Addiction

 

For details on the articles, please visit this link :: http://bit.ly/1NS4fUV

 

New Issue ::: Current Tissue Engineering

Current Tissue Engineering is an international peer-reviewed journal, which publishes expert reviews, original research articles, drug clinical trial studies and thematic issues in all areas of tissue engineering research. The scope includes, scaffold materials and synthesis, assembly methods, tissue culture and regeneration, artificial organs, bioreactors, and stem cells.

Articles from the journal Current Tissue Engineering, Volume 5 Issue 1:

• Editorial (Thematic Issue: Regenerative Medicine in Orthopedic Applications (Part II))
• Bone Regeneration: Microparticulate and Biomimetic Strategies
• Osteogenic Differentiation of Orofacial Tissue-Derived Mesenchymal Stem Cells- A Review
• Multi-Layered Scaffold to Mimic Hyaline Articular Cartilage Architecture
• Editorial: Regenerative Medicine for Retinal Diseases
• Current Development in Encapsulated Cell Therapy for Degenerative Retinopathies
• Adult Retinal Ganglion Cell Axon Regeneration and Re-innervation
• Regenerative Medicine in Retina: The Future Cure
• Stem Cells for Microenvironmental Modulation and Retinal Regeneration
• Mesenchymal Stem Cells Targeting of Systemic Disorders in Age-related Macular Degeneration

 

For details on the articles, please visit this link :: http://bit.ly/1Srndr5

New Issue ::: Combinatorial Chemistry & High Throughput Screening

Combinatorial Chemistry & High Throughput Screening(CCHTS) publishes full length original research articles and reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research.

Articles from the journal Combinatorial Chemistry & High Throughput Screening, Volume 19 Issue 3:

• Editorial: Validate and Verify: Keys to Scientific Excellence
• High Throughput Screening for Colorectal Cancer Specific Compounds
• An Efficient Four-Step Approach Toward Fused Triazino[1,6-a] Quinazolines
• Synthesis and Antifeedant Activities of Rosin-Based Esters Against Armyworm
• Comprehensive Chemical Profiling of Picrorhiza kurroa Royle ex Benth Using NMR, HPTLC and LC-MS/MS Techniques
• Identification of Potent Virtual Leads Specific to S1’ Loop of ADAMTS4: Pharmacophore Modeling, 3D-QSAR, Molecular Docking and Dynamic Studies
• Structure-Based Virtual Screening for Defeating Drug Resistant Form of EGFR Protein
• Fragment-Based De Novo Design of Antimycobacterial Agents and In Vitro Potency Evaluation
• Insights from Analysis of Binding Sites of Human Meprins: Screening of Inhibitors by Molecular Dynamics Simulation Study

 

For details on the articles, please visit this link :: http://bit.ly/1T3QHXQ

62-mile Lake discovered beneath Antarctica’s Ice!

The Antarctic ice conceals a smorgasbord of secrets.

Once a warm forested part of the world during the age of the dinosaurs, many fossils of which are just waiting to be excavated, it also features the world’s largest canyon system and a treasure trove of meteorites that were forged in the fiery furnace at the beginning of the Solar System.

There are also liquid freshwater lakes beneath the surface of the icy realm. Lake Vostok is probably the most well-known: After being left undisturbed for around 25 million years, scientists were overcome with curiosity and it was carefully breached.
Now it appears that researchers have another subterranean lake to add to their increasingly diverse collection of hidden geological gems. As revealed by the research team at the annual gathering of the European Geophysical Union (EGU) in Vienna, it is second only in size to the enormous Lake Vostok.

Ice at the surface is shaped by what type of rock it’s resting on, so by looking at unusual geographic features using ground-penetrating radar, scientists are able to make good guesses as to what may be concealed beneath. This time around, a collection of grooves at the surface revealed to the international team – who were in fact responsible for the canyon discovery last year using the same method – that a sub-glacial lake, complete with its own channels, still exists beneath the ice.

The Discovery:

The lake itself is around 100 kilometers (62 miles) long, 10 kilometers (6.2 miles) wide, and is ribbon-shaped. It also appears connected to the canyon, and channels leading away from it may be transporting water towards the West Ice Shelf and into the ocean.
The researchers, from UK, China and the US, are meeting soon to discuss the radar data that they have independently gathered, in order to try and absolutely confirm the existence of both the canyon system and the sub-glacial lake. Both would be of immense interest to biologists, who are keen to explore ecosystems that have remained untouched for tens of millions of years.

Whether or not these newly-discovered regions contain life is yet to be seen, however, this possibility isn’t particularly an unlikely one. The research team investigating Lake Vostok, for example, have found hints that simple microbes could still be thriving at these icy depths.

The exploration of this lake beneath the huge ice surfaces will unveil many hidden mysteries in that region.

A very Happy Birthday to Dr. Eduardo Ruiz- Hitzky!

Editor-in-Chief: Recent Patents on Nanotechnology

Eduardo Ruiz- Hitzky

Department of New Architectures in Materials Chemistry
Materials Science Institute of Madrid
Madrid, Spain

Open Access Article – “Recent Innovations in Cancer Chemotherapy by Nanomedicines”

Journal: Current Nanomedicine

Author(s): Hiraku Onishi and Yoshiaki Machida

Abstract

Background: Various drug delivery systems of antitumor drugs have been developed for past several decades. Nanomedicines, being one of promising choices, have been attracting much attention for the purpose of improving clinical use; because, they sometimes exhibit superior potentiality of enhanced efficacy and reduction of toxicity. Recently, many nanomedicines have been found to have useful results in the preclinical studies, and reached clinical trials or clinically-available stages. As there are few overviews for such situation, the brief explanation of such promising nanomedicines has been performed in this review.

Read more here: http://benthamscience.com/journals/current-nanomedicine/volume/6/issue/1/page/43/

Current Nanomaterials, Volume 1 – Number 1

“Recent Developments in the Green Syntheses of Chalcogenide Based Semi-conductor Nanoparticles”

Abstract:

Method: In this review, an attempt has been made to survey the recent work of green syntheses on metal-chalcogenide nanoparticles by different routes. The aqueous approach is an advantageous alternative to the conventionally used organometallic route, mainly due to its scalability, environmental friendliness, cost effectiveness and more importantly, the biocompatibility.

Read more here: http://benthamscience.com/journals/current-nanomaterials/volume/1/issue/1/page/12/

Open Access Article “Organizational Impact of the Introduction of a New Portable Syringe Pump for Iloprost Therapy in Italian Hospital Settings”

Journal: Current Drug Therapy

Abstract

Purpose: The study aims at assessing the organizational and economic impact related to the use of a new portable syringe pump (Pompa Infonde^®, Italfarmaco S.p.A., Cinisello Balsamo, Italy) at a hospital level.

Methodology: Based on the HTA approach, the analysis assessed the organizational and economic impact of the new device at hospital level, using the traditional methods of Iloprost infusion as comparator. After a pilot evaluation, the organizational impact was assessed within 24 Italian hospitals. Structured interviews were conducted with clinicians and nurses. According to the Hospital-Based HTA approach, a questionnaire assessed the impact on human resources, training activities, internal meetings, spaces needed, facilities, clinical practice implications. Using Activity Based Costing approach, the economic evaluation was performed within the pilot center “Ospedale Civile” of Legnano, Italy.

See more here: http://benthamscience.com/journals/current-drug-therapy/volume/10/issue/2/page/105/

Happy birthday to Dr. Lois T. Flaherty!

Editor-in-Chief – Adolescent Psychiatry

Lois T. Flaherty

Harvard University Medical School
Cambridge, MA
USA

 

Swim Towards A Healthy Life!

When I was ten years old I had my first ever experience of stepping into a swimming pool. The experience of learning to swim was so overwhelming that since then I have been advocating it as the best exercise and pastime for everyone. Swimming is the best because it is the easiest to adopt; all you need is a pool of water or a safe natural water source. You just have to learn to float and that’s the only part people find hard. Once it is learned, you can try all the strokes that you watch your favorite swimmers sporting.

Swimming is highly recommended by the doctors and laypeople alike, but why? Here we have some answers for this why.

• Fun – Humans have a natural fondness for water. The idea of stepping into a pool is mostly pretty exhilarating for our mind. We feel free and utterly relaxed while immersed in water. No wonder we have a variety of water sports that are absolutely wildly followed.
• Relief from pain – Back pain or any other sprain we have in our body gets a soothing feel in the water. As the body heat gets expelled in water, a relieving cool takes its place.
• Strength in muscles – Movement in water makes us exert energy and thus makes almost every muscle in the body strive to push us forward. This especially applies to the times when we have to immerse deeper towards the ground underneath. Shoulders, arms and legs simultaneously take the toll and make themselves stronger.
• Good for pregnant women – At the time of expecting, often doctors prescribe the women to try water aerobics. Exercising in water helps them get stronger abdominal muscles as well as all other aching muscles. The joints that are stressed out also find it relaxing.

Swimming is about a lot more benefits than stated. Do you have any to share?