EDITOR’S CHOICE – Stereoselective Reactions Catalyzed by N-Heterocyclic Carbenes

Journal: Mini-Reviews in Organic Chemistry

Author(s):  Xiao-Hua Cai*, Bing Xie

Graphical Abstract:



N-Heterocyclic carbenes (NHCs) as one of the most powerful reagents, ligands and organocatalysts for various reactions have been widely used in modern synthetic applications. Especially, the chiral NHCs have attracted intense attention in stereoselective reactions from synthetic chemists based on their highly efficiency and unique catalytic properties with excellent diastereoselectivity and enantioselectivity. A great deal of exciting achievements in the synthesis and applications of chiral NHC catalysts have been attained over the past decades. This review will mainly summarize recent advances in the chiral NHC-catalysed stereoselective reactions according to the use of NHCs including the generation of equivalents acyl anions, homoenolates, azolium enolates/acyl azoliums and oxidative NHC catalysis.

Read more here: http://www.eurekaselect.com/156466/article


Author: Bentham Science Publishers

A major STM journal publisher of more than 100 online and print journals and related print/online book series, Bentham Science answers the information needs of scientists in the fields of pharmaceutical, biomedical, medical, engineering, technology, computer and social sciences.

Leave a Reply

Please log in using one of these methods to post your comment:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: