Month: February 2019

Bentham Science Free Trial in Jinan University | Free Trial ends on May 25, 2019


Jinan University (abbreviated JNU) is a public research and comprehensive university based in Tianhe District, Guangzhou city, Guangdong province, China. It is one of the oldest universities established on China tracing back to the Qing dynasty (1644–1911).

Jinan University was founded in 1906 in Nanjing, whose mission is to spread Chinese learning and culture from North to South, and from China overseas. It is the first university in China to recruit foreign students, and is currently a Chinese university with the largest number of international students.

Jinan University is currently administered by both the Overseas Chinese Affairs Office of the State Council and the Chinese Ministry of Education. In 1996, it was included in the state’s Project 211 for development of key universities. In 2017, it was listed as one of the “double first-class universities”.

Jinan University has a lot of famous subjects home and aboard, such as Science of Medicine, Pharmaceutical Science, Science of Chemistry, Science of Engineering, Science of Economics, Science of Finance, Science of Journalism and Communication. And Chinese Language and Literature, specially Overseas Chinese Language, is the characteristic subject of JNU.



Press Release | The landscape of protein tyrosine phosphatase (Shp2) and cancer


As the proteomics technology develops and human genomic analysis becomes easier to execute, molecules involved in the regulation of biochemical signaling pathways have become interesting subjects for researchers. Earlier research was based on assumptions that metabolic cascades such as phosphorylation was linear. However, current studies indicate a multi-network signaling cascade. The interlinked signals performing in synchrony can be observed being responsive to a stimulus during physiological regulation. Although phosphatase is not considered as an inert house-keeping enzyme in the process of phosphorylation and regulation, its catalytic and regulatory actions show an involvement in signal transduction pathways. The key role of phosphatases is now defined to maintain and regulate the degree of signal’s intervals. According to recent studies, Shp2, a phosphatase protein has shown to have a remarkable role in governing the signaling response amplitude.




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Editor’s Choice Article | Design, Microwave Assisted Organic Synthesis and Molecular Docking Studies of Some 4 – (3H)-Quinazolinone Derivatives as Inhibitors of Colchicine- Binding Site of Tubulin

Author(s): Rakesh D. Amrutkar*, Mahendra S. Ranawat.


Currently, new chemical entities developed as anticancer agents against tubulin as a protein target. The present work, a quinazoline derivatives were used to design and synthesized by microwave irradiation as an anticancer agent through selective inhibitors of colchicinebinding site of tubulin by the molecular docking of quinazoline derivatives using Schrödinger, LLC, New York, NY, 2017. Read out full article here:



Bentham Science Free Trial in Warsaw University of Technology | Free Trial ends on April 10, 2019


The Warsaw University of Technology is one of the leading institutes of technology in Poland and one of the largest in Central Europe. It employs 2,453 teaching faculty, with 357 professors (including 145 titular professors). The student body numbers 36,156 (as of 2011), mostly full-time. There are 19 faculties (divisions) covering almost all fields of science and technology. They are in Warsaw, except for one in Płock.

The Warsaw University of Technology has about 5,000 graduates per year. According to the 2008 Rzeczpospolita newspaper survey, engineers govern Polish companies. Warsaw Tech alums make up the highest percentage of Polish managers and executives. Every ninth president among the top 500 corporations in Poland is a graduate of the Warsaw University of Technology. Professor Kurnik, the rector, explained that the school provides a solid basis for the performance of managers by equipping its students with an education at the highest level and a preparation with the tools and information, including knowledge of foreign languages.



Bentham Science Free Trial in King Faisal University | Free Trial ends on April 22, 2019


King Faisal University (KFU) is a public university with the main campus in the city of Hofuf in Al Ahsa, Saudi Arabia founded in 1975. KFU was initially established with four colleges: two in Dammam and the other two in Al-Ahsa. Later, the colleges in Dammam have been segregated to become the University of Dammam.

The University has also given special attention to conferences and symposia in scientific and cultural enrichment of knowledge and community service. It has organised more than 66 local and global conferences symposia. Additionally its faculty members have been represented at more than 300 scientific conference and a symposium at home and abroad.

This meant such beneficiaries as computer applications and expanded uses at the administrative and academic level to contribute to automated and streamlined administrative and academic management decisions, including the following regulations: automated information systems at the university level, students’ record system, system stores procurement, financial system, a patient care system, and architectural designs.

In terms of ranking, KFU has been ranked #22 in QS Ranking for Arab Region 2016. By 2010 the number of colleges at KFU has risen to 14.





Aims & Scope | Current Analytical Chemistry


Current Analytical Chemistry publishes expert reviews and original research articles on the most recent advances in analytical chemistry. All aspects of the field are represented, including analytical methodology, techniques, and instrumentation in both fundamental and applied research topics of interest to the broad readership of the journal. Current Analytical Chemistry strives to serve as an authoritative source of information in analytical chemistry and in related applications such as biochemical analysis, pharmaceutical research, quantitative biological imaging, novel sensors, and nanotechnology.



Most Accessed Articles | Colorimetric Sensing of Iodide by the Competitive Interactions in the Surface of Gold Nanoparticles with the Simultaneous Aggregation/ Anti-Aggregation Mechanisms in Edible Salts

Author(s): Zolaikha Rasouli, Raouf Ghavami*.


Iodide (I-) is a vital micronutrient and its essential roles have been approved in a number of neurological activities. Therefore, there is a growing interest in developing reliable sensitive quantitative methodologies for the determination of the amount of I- in edible salt samples.

First, 2heDTC was synthesized by the mixing of equivalent amounts of pure C2H7NO and CS2 in the presence of NH4OH under vigorous stirring in an ice bath. Then, AuNPs were synthesized; the 250 mL of 1 mM HAuCl4 was put into a round-bottomed flask and was boiled vigorously by stirring for 20 min. Then, 25 mL of 38.8 mM of Na3C6H5O7 was added rapidly into this solution. The solution was heated under reflux for another 15 min. The modification of the AuNPs surface was performed with 2heDTC by proceeding with the ligand exchange reaction. To the quantification of I-, 2 µL (1mM) Hg2+ was added to 0.5 mL (50 mM) of PBS solution with pH = 5.0 containing 500 µL of 2heDTC-AuNPs, which was then maintained at optimized time for the creation of bare AuNPs. Then, the different concentrations of I- were separately added. Finally, the surface plasmon resonance (SPR) absorption bands were taken with UV-Vis spectrophotometer. Read out full article here:


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Open Access Articles | Simultaneous Quantification of Citalopram and its Main Metabolite, Desmethylcitalopram, in Human Saliva by UHPLC

Author(s): Ewelina Dziurkowska, Marek Wesolowski*.

Journal Name: Current Analytical Chemistry

This study was designed to develop a reliable method for simultaneous quantitation of Citalopram (CIT) and its main active metabolite, Desmethylcitalopram (DCIT), in saliva of patients undergoing treatment with CIT.

To compare two procedures of saliva purification, Solid-Phase (SPE) and Liquid-Liquid (LLE) extractions, saliva samples obtained from healthy volunteers were spiked with adequate quantities of CIT and DCIT. Different cartridges were used for SPE, while dichloromethane for LLE. Chromatographic separation and quantitation were carried out by UHPLC with DAD detector using a C-18 column and a mixture of acetonitrile and redistilled water (37:63, v:v) with the addition of formic acid (pH 3.5) as a mobile phase. Read out full article here:



Editor’s Choice Article | Graphene Quantum Dots in Electrochemical Sensors/Biosensors

Author(s): Farnoush Faridbod*, Afsaneh L. Sanati.


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Graphene and its derivatives, as most promising carbonic nanomaterials have been widely used in design and making electrochemical sensors and biosensors. Graphene quantum dots are one of the members of this family which have been mostly known as fluorescent nanomaterials and found extensive applications due to their remarkable optical properties. Quantum confinement and edge effects in their structures also cause extraordinary electrochemical properties. Read out full article here:

Bentham Science Free Trial in University of San Diego – Copley Library| Free Trial ends on May 18, 2019


The Helen K. and James S. Copley Library, located on the west end of the campus, currently houses over 500,000 volumes. Collections include books, journals, reference works, databases, government documents, newspapers and electronic journals in many languages, as well as maps, videos, sound recordings, micro-forms and rare books.



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