Journal Name: Current Green Chemistry

 

Author(s): Anindita Mukherjee, Nirnita C. Ghosal, Grigory V. Zyryanov, Adinath Majee*, Sougata Santra*

Graphical Abstract:

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Abstract:

Aziridines are highly versatile intermediates in organic synthesis due to their easy access and their susceptibility to ring-opening by facile C-N bond cleavage. They are synthetically very important as they are valuable precursors of amino sugars, β-lactam antibiotics and alkaloids or present in various natural products that exhibit potent biological activities. The synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here, a short review has been reported on the synthesis of this scaffold employing different strategies under different greener conditions. Various methods have been developed in the presence of green catalysts and solvents.

 

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