Search for new inhibitors of MurA

What is it about?

Research for new antibacterial agents is ongoing because of the resistance of bacteria to current antibiotics. In this research, we tried to find new antibacterial agents by starting with a bioinformatic method “virtual screening” targeting MurA, and then we completed with a biological test on bacteria.

Why is it important?

As result, four compounds had antibacterial activity, one of them carried out its activity with MIC 457μg/ml against Staphylococcus aureus. Read more about the article here:

Author: Bentham Science Publishers

A major STM journal publisher of more than 100 online and print journals and related print/online book series, Bentham Science answers the information needs of scientists in the fields of pharmaceutical, biomedical, medical, engineering, technology, computer and social sciences.

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