Most Cited Articles: A Mini-Review: Achievements in the Thiolysis of Epoxides

Journal Name: Mini-Reviews in Organic Chemistry

Author(s):Zhihua ChenSaeed Mohammadi NasrMosstafa Kazemi* and Masoud Mohammadi

DOI: 10.2174/1570193X16666190723111746


The β-hydroxy sulfides are an important class of organosulfur compounds that have a key role in the synthesis of bioactive compounds containing biological and natural products. The thiolysis of epoxides is the most common and best route for the synthesis of β-hydroxy sulfides. During the last decade, the applications of a diverse range of catalysts and promoter agents in green and organic mediums as well as under solvent-free conditions for the regioselective ring-opening reactions of epoxides with thiols in order to synthesize β-hydroxy sulfides have been studied by various research groups. This review is focused on the important achievements reported in the literature for the thiolysis of epoxides. Access here:

Author: Bentham Science Publishers

A major STM journal publisher of more than 100 online and print journals and related print/online book series, Bentham Science answers the information needs of scientists in the fields of pharmaceutical, biomedical, medical, engineering, technology, computer and social sciences.

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