EDITOR’S CHOICE – Differences in Relative Levels of 88 microRNAs in Various Regions of the Normal Adult Human Brain – MicroRNA

Journal: MicroRNA

Author(s): Elena V. Filatova, Anelya Alieva, Maria I. Shadrina, Petr A. Slominsky.

Graphical Abstract:

 

Abstract:

Aim of Study: Since the discovery of microRNAs (miRNAs) in the 1990s, our knowledge about their biology has grown considerably. The increasing number of studies addressing the role of miRNAs in development and in various diseases emphasizes the need for a comprehensive catalogue of accurate sequence, expression and conservation information regarding the large number of miRNAs proposed recently in all organs and tissues. The objective of this study was to provide data on the levels of miRNA expression in 15 tissues of the normal human brain.

Materials and Methods: We conducted an analysis of the relative levels of 88 of the most abundantly expressed and best characterized miRNA derived postmortem from well-characterized samples of various regions of the brains from five normal individuals.

Results: The cluster analysis revealed some differences in the relative levels of these miRNAs among the brain regions studied. Such diversity can be explained by different functioning of these brain regions.
Conclusion: We hope that the data from the current study are a resource that will be useful to our colleagues in this exciting field, as more hypotheses will be generated and tested with regard to small noncoding RNA in the human brain in healthy and disease states.

 

HIGHLIGHTED ARTICLE – THE BLOOD BRAIN BARRIER AND ITS ROLE IN ALZHEIMER’S THERAPY – CURRENT DRUG TARGETS

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https://benthamscience.com/journals/current-drug-targets/special-issues/#top

UPCOMING THEMATIC ISSUE – BOTANICALS: INNOVATIVE TOOLS FOR PHARMACEUTICAL, COSMETIC AND NUTRACEUTICAL – CURRENT MEDICINAL CHEMISTRY

CMC-THEMATIC FLYER -Prof.Carmelo Puglia

https://benthamscience.com/journals/current-medicinal-chemistry/special-issues/

TESTIMONIAL BY ARCHANA CHAUDARY!

Archana Chaudhary

Contributed Article: “Immunomodulatory Role Of Arsenic On Regulatory T Cells

 

 

NEW ISSUE :: Recent Advances in Electrical & Electronic Engineering 10, Issue 2

Recent Advances in Electrical & Electronic Engineering publishes review and research articles, guest edited thematic issues, and reviews on patents on electrical and electronic engineering and applications. The journal also covers research in fast emerging applications of electrical power supply, electrical systems, power transmission, electromagnetism, motor control process and technologies involved and related to electrical and electronic engineering.

The journal is essential reading for all researchers in electrical and electronic engineering science.

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Articles from the journal Recent Advances in Electrical & Electronic Engineering, Volume 10, Issue 2:

For details on the articles, please visit this link :: http://bit.ly/2yy0Gqx

ARTICLE TO READ ON WORLD DIABETES DAY

Epidemiology of Diabetes Mellitus in the United Arab Emirates

Journal: Current Diabetes Reviews

Author(s): Hira Abdul Razzak, Alya Harbi, Wael Shelpai, Ahmad Qawas

Abstract:

Background/ Objective: Diabetes mellitus is a non-communicable disease which has become a major global public health issue. This systematic review summarized epidemiological studies related to the prevalence, risk factors, complications, incidence, knowledge, attitude and practices of Diabetes Mellitus (DM) among Arab population in the United Arab Emirates (UAE).

Method: PubMed, Scopus databases, Science direct, Wiley online library, and other local journals were searched to identify relevant literature using appropriate keywords to retrieve studies conducted in the UAE. Search limits were restricted to studies in English language, between 2007 and 2016, and on UAE population (both citizens and expatriates).

Results: Electronic database search yielded 24 studies about the prevalence, incidence, complications, risk factors, knowledge, attitudes and practices of diabetes, including cross sectional studies (n =18), population-based survey (n = 1), retrospective cohort studies (n = 3), qualitative (n=1), and randomized controlled trial (n = 1). Countrywide prevalence estimates of Diabetes Mellitus were reported to be high. The major determinants of Diabetes Mellitus involved hypertension, physical inactivity, sedentary lifestyle, and unhealthy diet.

Conclusion: Even though past evidences have promulgated the role of numerous causative factors, the epidemiological implications of some of the risk factors including family history, educational level, and the use of alcohol remains elusive. This systematic review signifies epidemiology of Diabetes Mellitus in the United Arab Emirates and suggests that extra efforts are needed for preventive and curative strategies in order to decrease the burden of this non-communicable disease.

Read more here: http://www.eurekaselect.com/155750

 

World Diabetes Day 2017!

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World Diabetes Day acknowledges the severity of diabetes mellitus as a disease that effects the health of many all over the world. Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. If left untreated, diabetes can cause many complications.

Bentham Science publishes papers from prominent medical researchers to find remedies for diabetes. For the best published articles view the following journal:

Current Diabetes Reviews

INFOGRAPHIC: WORLD DIABETES DAY

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Image Credits: International Diabetes Federation

TESTIMONIAL BY STEVEN L. PARKER!

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Contributed Article: “Canonical microRNA Matching Differs Greatly Across Groups of G-protein Coupled Receptor mRNAs

NEW ISSUE :: CURRENT MEDICINAL CHEMISTRY 24, ISSUE 26

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

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Articles from the journal Current Medicinal Chemistry, Volume 24, Issue 26:

For details on the articles, please visit this link :: http://bit.ly/2j4kF9q