New Issue | Current Organic Chemistry; Volume 23 Issue 25




Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.


Articles from the journal: Current Organic Chemistry; Volume 23 Issue 25

For details on the articles, please visit this link:

Most Cited Articles | Transition Metal Catalyzed Aerobic Asymmetric Coupling of 2-Naphthols

Journal Name: Mini-Reviews in Organic Chemistry

Author(s): Nikolay V. Tkachenko*, Konstantin P. Bryliakov*.





Optically pure 1,1′-bi-2-naphthol (BINOL) and its derivatives are among the most widely used chiral ligands and auxiliaries for asymmetric synthesis. These molecules also occur as scaffolds for various biologically active compounds. Direct oxidative coupling of 2-naphthols in the presence of chiral catalysts provides a powerful strategy for the synthesis of optically pure 1,1′-bi-2-naphthols (BINOLS). In 1978, Wynberg with co-workers discovered that a copper salt with chiral auxiliary mediates the oxidative coupling of 2-naphthols, which can be taken as the starting point for further progress in this area. Over the last decades, a number of efficient and stereoselective catalyst systems have been developed. This mini-review surveys the aerobic asymmetric oxidative coupling of 2-naphthols catalyzed by transition metal complexes reported since 1995. To read out more, please visit:

Editor’s Choice – A Review on Advances in Organoborane-Chemistry – Current Organic Synthesis

Journal: Current Organic Synthesis

Author(s): Paranjeet Kaur, Gopal L. Khatik, Surendra Kumar Nayak.

Graphical Abstract:



Background: In the past decades, the hydroboration reaction was serendipitously discovered which occurred by the facile addition of diborane to alkenes and alkynes. Hydroboration reactions produce organoboranes. The organoboranes have marked a new era in the field of organic chemistry because they are versatile chemical intermediates that are readily available to chemists.

Objective: The review focuses on recent advancements in organoborane reagents in asymmetric synthesis. We searched the scientific database using relevant keywords such an asymmetric hydroboration, organoboranes etc. The quality research papers were included in the review which discusses the asymmetric synthesis via organoborane compounds.

Conclusion: The development of organoborane compounds increased remarkably in few years after hydroboration reaction discovered. Later on, new selective hydroboration agents were developed (for example thexylborane, disiamylborane, dipinylborane, 9-borabicyclenonane, and diisopinocamphylborane which have proven valuable in syntheses of organic compounds with new carbon-carbon bonds. H.C Brown and his co-workers established various procedures to synthesize asymmetric compounds with high enantiomeric excess (ee). There are many different types of strategies in the asymmetric syntheses, but asymmetric syntheses via chiral organoborane reagents have proven to be truly general and have been used to achieve reactions resulting in excellent ee. This review focuses on the advancement.

Highlighted Article Flyer for the journal “Current Organic Synthesis”



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