eBook Highlights| Topics in Anti-Cancer Research -Volume 7

The seventh volume of the series covers topics such as drug delivery, new avenues for treatment of esophageal cancer and the role of nutrigenomics in finding new therapies.

Topics in Anti-Cancer Research covers important advances on both experimental (preclinical) and clinical cancer research in drug development. The book series offers readers an insight into current and future therapeutic approaches for the prevention of different types of cancers, synthesizing new anti-cancer agents, new patented compounds, targets and agents for cancer therapy as well as recent molecular and gene therapy research.

The comprehensive range of themes covered in each volume will be beneficial to clinicians, immunologists, and R&D experts looking for new anti-cancer targets and patents for the treatment of neoplasms, as well as varied approaches for cancer therapy.

The latest volume of the series starts with a review on non-coding RNAs and associated patents. These patents help researchers to identify various cancer biomarkers and oncogenic regulatory mechanisms. 3 chapters cover nanocarrier patents for enhanced drug delivery of chemotherapeutic agents. Nanocarriers allow drug manufacturers to encapsulate chemotherapeutic agents within thin membranes which allows the molecules to reach the targeted cellular location in the body. The specific topics refer to Nanotaxol which is a nanotechnology enhanced version of Taxol® – a chemotherapeutic agent derived from chemicals in the bark of Taxus brevifolia, stimuli responsive nanocarriers which change behavior according to temperature and pH and smart nanoformulations which rely on different chemical formulations to reach molecular targets. Other topics covered in this volume include the role of autophagy in esophageal cancer, and nutrigenomics (the science of how biological nutrients affect gene expression) in cancer research. In terms of patents, the reader will find a list of compounds which modulate autophagy, and nutrigenomic methods that allow researchers to understand nutritional biomarkers of disease and customize nutraceutical formulations based on genetic and metabolic factors, respectively. To read out more, please visit: https://ebooks.benthamscience.com/book-highlights/190102001/

 

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Most Accessed Articles | Synthesis and Biological Evaluation of PF-543 Derivative

 

Journal Name: Letters in Organic Chemistry

Author(s): Seon Woong Kim, Taeho Lee, Joo-Youn Lee, Sanghee Kim, Hee-Sook Jun, Eun-Young Park*, Dong Jae Baek*.

 

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PF-543 has been known as a substance that strongly inhibits SK1. However, it also exhibits antineoplastic activity that is lower than other inhibitors of SK1. In this study, we compared PF-543 and synthesized a newly designed derivative of PF-543 (compound 2) in which two aromatic structures were connected in para-form. The synthesized derivative showed inhibitory effect on SK1, similar to that of PF-543. However, it was more cytotoxic to HT29, AGS, and PC3 cells than PF-543. We also carried out a docking study for SK1 and demonstrated that the synthesized derivative showed interaction with SK1 similar to PF-543. Results obtained from this study suggest that the structure of compound 2 may be well substituted for the structure of PF-543 in terms of biological activity, providing us important structural information for the design of new derivatives of PF-543. Read out full article here: http://www.eurekaselect.com/166082

 

Open Access Articles | Synthesis of 1-(3-Phenylpropyl)-4-(pyridinylmethoxy)-[1,2,4]triazolo[4,3-a] quinoxalines

 

Journal Name: Letters in Organic Chemistry

Author(s): Dominik Summer, Barbara Matuszczak*

 

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Starting from 2,3-dichloroquinoxaline, a synthetic strategy for the preparation of 1-(3- phenylpropyl)-4-(pyridinylmethoxy)[1,2,4]triazolo[4,3-a]quinoxalines is described. Read out full article here:  http://www.eurekaselect.com/163737

 

 

 

 

 

New Issue | Current Topics in Medicinal Chemistry; Volume: 19, Issue: 6

 

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

 

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Articles from the journal: Current Topics in Medicinal Chemistry; Volume: 19, Issue: 6

 

For details on the articles, please visit this link: http://www.eurekaselect.com/node/615/current-topics-in-medicinal-chemistry/issue/19/2599/6/9078

 

 

 

Wishing you a very Happy Birthday | Dr. Seetak Dodd

 

Dr. Seetaak Dodd

 

Dr. Seetak Dodd

Editor in Chief: Current Drug Safety

University of Melbourne
Geelong, Melbourne
Australia

Become an Editorial Board Member (EBM) | Current Pharmaceutical Design

 

Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Abstracted and Indexed in:

  • Science Citation Index Expanded (SciSearch®)
  • Science Citation Index®
  • Journal Citation Reports/Science Edition
  • InCites
  • Biochemistry & Biophysics Citation Index®
  • Current Contents® – Life Sciences
  • Medical Documentation Service®
  • Research Alert®
  • Index to Scientific Reviews®
  • Custom Information Services®
  • BIOSIS
  • BIOSIS Previews
  • BIOSIS Reviews Reports and Meetings
  • MEDLINE/PubMed/Index Medicus
  • Scopus
  • EMBASE/Excerpta Medica
  • Chemical Abstracts Service/SciFinder
  • Cambridge Scientific Abstracts (CSA)/ProQuest
  • ChemWeb
  • Google Scholar
  • PubsHub
  • Index Copernicus
  • MediaFinder®-Standard Periodical Directory
  • Genamics JournalSeek
  • J-Gate
  • CNKI Scholar
  • Suweco CZ
  • TOC Premier
  • EBSCO
  • Ulrich’s Periodicals Directory
  • JournalTOCs

 

The Journal is interested in appointing active Editorial Board Members on the Journal’s Board. If you are working in the mentioned field of the journal and are interested in becoming an Editorial Board Member, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field of interest then please feel free to recommend suitable colleagues for the Editorial Board membership of the journal and, if possible, send us their CV along with their list of publications at hermain@benthamscience.net and CC faizan@benthamscience.net, mentioning in the subject line, the field of interest. The responsibilities of Editorial Board Members will be discussed in details further after this stage.

 

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Become a Reviewer | Current Pharmaceutical Design

 

Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Abstracted and Indexed in:

  • Science Citation Index Expanded (SciSearch®)
  • Science Citation Index®
  • Journal Citation Reports/Science Edition
  • InCites
  • Biochemistry & Biophysics Citation Index®
  • Current Contents® – Life Sciences
  • Medical Documentation Service®
  • Research Alert®
  • Index to Scientific Reviews®
  • Custom Information Services®
  • BIOSIS
  • BIOSIS Previews
  • BIOSIS Reviews Reports and Meetings
  • MEDLINE/PubMed/Index Medicus
  • Scopus
  • EMBASE/Excerpta Medica
  • Chemical Abstracts Service/SciFinder
  • Cambridge Scientific Abstracts (CSA)/ProQuest
  • ChemWeb
  • Google Scholar
  • PubsHub
  • Index Copernicus
  • MediaFinder®-Standard Periodical Directory
  • Genamics JournalSeek
  • J-Gate
  • CNKI Scholar
  • Suweco CZ
  • TOC Premier
  • EBSCO
  • Ulrich’s Periodicals Directory
  • JournalTOCs

 

The Journal is interested in appointing active Reviewers on the Journal’s Board. If you are working in the mentioned field of the journal and are interested in becoming a Reviewer, send us your CV at the below mentioned email. If, however, the scope of the journal is not directly related to your field of interest then please feel free to recommend suitable colleagues for the Reviewers for the journal and, if possible, send us their CV mentioning the field of interest at your earliest convenience at hermain@benthamscience.net and CC faizan@benthamscience.net.

 

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What is fatty liver?

11056074_10153593971002612_7062337007636128473_osource: Medical Observer

BSP Following Recent Issues have been Published

Current Respiratory Medicine Reviews, 9 Issue 5

7-14-2014 8-47-55 AM

Editor-in-Chief:

Joseph Varon

The University of Texas Health Science Center
Houston, TX
USA

Aims & Scope

Current Respiratory Medicine Reviews publishes original research papers, frontier reviews, drug clinical trial studies and guest edited issues dedicated to clinical research on all the latest advances on respiratory diseases and its related areas e.g. pharmacology, pathogenesis, clinical care, therapy. The journal is essential reading for all researchers and clinicians in respiratory medicine.

www.eurekaselect.com

Abstracted & Indexed in:

Chemical Abstracts, Scopus, EMBASE, CINAHL®, EMNursing, PubsHub, Genamics JournalSeek, MediaFinder®-Standard Periodical Directory, J-Gate.

http://www.eurekaselect.com/122832/issue/5

For more information, visit: http://benthamscience.com/journal/index.php?journalID=crmr 

 

 Current Bioinformatics, 9 Issue 3

7-14-2014 8-50-44 AM

 Editor-in-Chief:

Alessandro Giuliani

Istituto Superiore di Sanitá (Italian NIH) Environment and Health Dept
Roma
Italy

Aims & Scope

Current Bioinformatics aims to publish all the latest and outstanding developments in bioinformatics. Each issue contains a series of timely, in-depth reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field, covering a wide range of the integration of biology with computer and information science.

The journal focuses on reviews on advances in computational molecular/structural biology, encompassing areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Developments in these fields have direct implications on key issues related to health care, medicine, genetic disorders, development of agricultural products, renewable energy, environmental protection, etc.

Current Bioinformatics is an essential journal for all academic and industrial researchers who want expert knowledge on all major advances in bioinformatics.

www.eurekaselect.com

 Abstracted & Indexed in:

Chemical Abstracts, EMBASE, Science Citation Index Expanded, BIOSIS, BIOSIS Previews, Biological Abstracts, Journal Citation Reports/Science Edition, Scopus, EMBiology, Genamics JournalSeek, MediaFinder®-Standard Periodical Directory, PubsHub, J-Gate.

http://www.eurekaselect.com/122838/issue/3

For more information, visit: http://benthamscience.com/journal/index.php?journalID=cbio

 Current Biotechnology , 3 Issue 2

7-14-2014 8-52-53 AM

Aims & Scope

Current Biotechnology is an international peer-reviewed journal, which publishes expert research, reviews and thematic issues in all core areas of biotechnology including basic and applied research. Topics covered include, molecular engineering of nucleic acids and proteins; genomics and bioinformatics, molecular therapy; imaging technology and large scale biology; medical biotechnology, regenerative medicine, industrial biotechnology, biochemical engineering/bioprocess engineering, nano-biotechnology, bio-nanotechnology, analytical biotechnology; food and agricultural biotechnology; environmental biotechnology.

www.eurekaselect.com

Abstracted & Indexed in:

Chemical Abstracts, J-Gate

http://www.eurekaselect.com/122848/issue/2

For more information, visit: http://benthamscience.com/journal/index.php?journalID=cbiot

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