HIGHLIGHTED ARTICLE – The Click Test – Current Aging Science

Cas-Articles_10-4-Mario Ubaldo Manto

To access the article, please visit: http://www.eurekaselect.com/152354

Social Support Crucial for Health in Old Age

‘Man is a social animal’ – this statement has become a cliché over time but still holds its significance. The reason is that it is as true in practice as it is in theory. We see in our surroundings that the people who have families around them who care for them are visibly more satisfied than the ones who are alone. Apart from family if they are getting support from their friends, neighbors and society, then they find it much easier to maintain their health and wellbeing.

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This topic has gained much attention from the social scientists as well as medical and life scientists, as they are curious to find the social factors and their correlations that are vital for human ageing, morbidity and mortality. The findings have been clear that the people who were old and had little access to others and social support were found more susceptible to ailments and were leading rapidly towards death. Whereas those older ones who had people near them to talk to them, hear and address their problems, provide emotional as well as social support, were more satisfied and more capable of keeping healthy for long.

One of the important researches finding this correlation is published in the journal, Current Aging Science journal and can be read here:

Support and Social Contact as a Decisive Meta-Variable in Morbidity and Social Welfare of the Older Person

Open Access Article – Developing the Transdisciplinary Aging Research Agenda: New Developments in Big Data – Current Aging Science

Journal: Current Aging Science

Author(s): Christian William Callaghan

Abstract:

Background: Advances in big data analytics can enable more effective and efficient research processes, with important implications for aging research. Translating these new potentialities to research outcomes, however, remains a challenge, as exponentially increasing big data availability is yet to translate into a commensurate era of ‘big knowledge,’ or exponential increases in biomedical breakthroughs. Some argue that big data analytics heralds a new era associated with the ‘end of theory.’ According to this perspective, correlation supersedes causation, and science will ultimately advance without theory and hypotheses testing. On the other hand, others argue that theory cannot be subordinate to data, no matter how comprehensive data coverage may ultimately become.

Objective: Given these two tensions, namely (i) between exponential increases in data that have not translated into exponential increases in biomedical research outputs; and (ii) between the promise of comprehensive data coverage and inductive data-driven modes of enquiry versus theory-driven deductive modes, this critical review seeks to offer useful perspectives of big data analytics and to derive certain theoretical implications for aging research.

Method: This work offers a critical review of theory and literature relating big data to aging research.

Results: The rise of big data provides important insights into the theory development process itself, highlighting potential for holistic theoretical assemblage to ultimately enable near real time research capability.

Conclusion: Big data may represent a new paradigm of aging research that can dramatically increase the rate of scientific breakthroughs, but innovative theory development remains key to this potential.

Read more here: http://www.eurekaselect.com/154309

 

Press Release for EurekAlert! Neuroinflammation in Alzheimer’s and Parkinson’s diseases

This article by Dr. Jordan A. McKenzie et al. is published in Current Aging Science, Volume 10, Issue 3, 2017

In the journal Current Aging Science, a research team has reviewed modifiable risk factors for Alzheimer’s and Parkinson’s diseases. The reviewers focus on the possible role of neuroinflammation (inflammation of the nervous tissue) in neurodegenerative disease mechanisms. Alzheimer’s disease and Parkinson’s disease are among the most common causes of dementia, and increasingly contribute to morbidity and mortality worldwide. A common hallmark of these two diseases is neuroinflammation, which is initially triggered by the presence of pathological molecular structures associated with these disorders. Chronic neuroinflammation is sustained by persistent activation of the non-neuronal glial cells in the brain, which results in damage or death of neighboring cells, including neurons and glial cells themselves. Persistent neuroinflammation of the brain is hypothesized to contribute to the neurodegeneration observed in Alzheimer’s and Parkinson’s diseases.

The reviewers note four modifiable risk factors for Alzheimer’s and Parkinson’s diseases: physical inactivity, vascular disease-related conditions, obesity and type two diabetes mellitus. These modifiable risk factors contribute to neuroinflammation through specific mechanisms that are directly linked to the pathologies of Alzheimer’s and Parkinson’s diseases. These risk factors are deemed modifiable as their occurrence in the general population can be reduced, or avoided by individuals, through various lifestyle changes, such as improved diet, regular exercise and effective treatment of vascular disease-related conditions such as high blood pressure. This review highlights that the control of the modifiable risk factors is a valid approach for managing the increased incidence of both Alzheimer’s and Parkinson’s diseases. In addition, the neuroinflammatory mechanisms common to Alzheimer’s and Parkinson’s diseases are described, which may link the above four common modifiable risk factors with both of these neurodegenerative diseases. A better understanding of the molecular mechanism of neuroinflammation could help identify new therapeutic targets for combating neurodegenerative diseases.

View the article here: http://www.eurekaselect.com/150884

Wishing A Very Happy Birthday to Prof. Debomoy K. Lahiri!

Prof. Debomoy k. Lahiri.jpg

Prof. Debomoy K. Lahiri

EDITOR-IN-CHIEF: Current Alzheimer Research & Current Aging Science

Department of Psychiatry Indiana University School of Medicine
Indianapolis, IN
USA

Highlighted Article – Neuron vs. Germline: A war of Hormetic Tradeoffs – Current Aging Science

cas-Articles-10 -4-2017-Marios Kyriazis

http://www.eurekaselect.com/151589/article

Highlighted Article Flyer for the journal “Current Aging Science”

cas-Articles-10 -4-2017-Luis Miguel Rondón García

http://www.eurekaselect.com/151590/article

New Issue :: Current Aging Science 10, Issue 2

Current Aging Science publishes frontier review and experimental articles in all areas of aging and age-related research that may influence longevity. This multidisciplinary journal will help in understanding the biology and mechanism of aging, genetics, pathogenesis, intervention of normal aging process and preventive strategies of age-related disorders. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, clinical, molecular, and animal models, including lower organism models (e.g., yeast, Caenorhabditis elegans and Drosophila). In addition to the affect of aging on integrated systems, the journal also covers original articles on recent research in fast emerging areas of adults stem cells, brain imaging, calorie restriction, immunosenescence, molecular diagnostics, pharmacology and clinical aspects of aging. Manuscripts are encouraged that relate to developmental programming of aging and the synergistic mechanism of aging with cardiovascular diseases, obesity and neurodegenerative disorders.

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Articles from the journal Current Aging Science 10, Issue 2:

                      For details on the articles, please visit this link :: http://bit.ly/2oHCHi6

 

Highlighted Article Flyer for the journal “Current Aging Science”

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http://benthamscience.com/journals/current-aging-science/

New Issue :: Current Aging Science 10, Issue 1

Current Aging Science publishes frontier review and experimental articles in all areas of aging and age-related research that may influence longevity. This multidisciplinary journal will help in understanding the biology and mechanism of aging, genetics, pathogenesis, intervention of normal aging process and preventive strategies of age-related disorders. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, clinical, molecular, and animal models, including lower organism models (e.g., yeast, Caenorhabditis elegans and Drosophila). In addition to the affect of aging on integrated systems, the journal also covers original articles on recent research in fast emerging areas of adults stem cells, brain imaging, calorie restriction, immunosenescence, molecular diagnostics, pharmacology and clinical aspects of aging. Manuscripts are encouraged that relate to developmental programming of aging and the synergistic mechanism of aging with cardiovascular diseases, obesity and neurodegenerative disorders.

Book reviews, meeting reports and letters-to-the-editor and drug clinical trial studies are also published. The journal is essential reading for researchers, educators and physicians with interest in aging, age-related dementia and Alzheimer’s disease and longevity. Current Aging Science provides a comprehensive coverage of the current state of aging research for gerontologists, neuroscientists, clinicians, health science planners, granting agencies and pharmaceutical scientists.

cas

Articles from the journal Current Aging Science 10, Issue 1:

For details on the articles, please visit this link :: http://bit.ly/2kyZ6fN