Prof. Jian’an Wang
EDITOR-IN-CHIEF: Current Cardiology Reviews
Dr. Jian’an Wang serves as the Editor-in-Chief of the journal.
Case Western Reserve University School of Medicine
Cleveland, OH
USA
Dr. Jian’an Wang serves as the Editor-in-Chief of the journal.
Case Western Reserve University School of Medicine
Cleveland, OH
USA
School of Medicine Zhejiang University
Hangzhou
China
World Heart Day is part of an international campaign to spread awareness about heart disease and stroke prevention. This is the perfect day to quit smoking, get exercising and start eating healthy – all in the name of keeping your ticker in good working order, and improving the health and well being of people the world over.
The World Heart Federation have found that heart disease and strokes are the world’s leading cause of death, killing 17.1 million people every year – that’s more than victims of cancer, HIV and AIDS and malaria.
Bentham Science publishes articles related to World Heart Day in its Subscription based journals including:
Journal: Current Cardiology Reviews
Author(s): Melvin Dziubek, Charalampos Pierrakos, Louis Chebli, Helene Demanet, Ahmed Sanoussi, Pierre Wauthy*
Background: Mitral para-prosthetic leaks are rare but major complications of mitral heart valve replacements. When they must be re-operated, they are burdened with high mortality rates. We proposed to review our surgical experience in terms of approach and type of operation carried out.
Methods: Demographic, preoperative, intraoperative and postoperative characteristics of 34 patients benefited from a surgical treatment of mitral paravalvular leak, at the Brugmann University Hospital between 1996 and 2016, have been analysed retrospectively. We analysed the data to identify the risk factors of postoperative mortality. We then compared the data depending on the approach and the type of surgical treatment in order to compare the morbidity-mortality.
Results: The postoperative mortality rate was 11.7%. The presence of endocarditis and increase in lactate dehydrogenase were predictive factors of mortality. Cardiac complications and acute kidney failure were significantly more common in the decease population. Direct mitral paravalvular leak suturing was more frequently performed on early apparition, anterior and isolated leaks, whereas a mitral heart valve replacement was most often performed to cure active primary endocarditis. The incidence of complications and mortality rates were identical according to the approach and the type of operation performed. A mitral para-prosthetic leak recurrence was observed in 33% of the cases.
Conclusion: Surgical treatment of mitral para-prosthetic leaks is accompanied by a high mortality rate. The operative strategy plays a major role and can influence the morbidity-mortality encountered in those patients.
Read more here: http://www.eurekaselect.com/156994/article
Current Inorganic Chemistry 7, Issue 2
https://bit.ly/2vfzagh
Current Cardiology Reviews 14, Issue 1
https://bit.ly/2EOoy7J
Current Proteomics 15, Issue 2
https://bit.ly/2EORnko
Mini-Reviews in Organic Chemistry 15, Issue 2
https://bit.ly/2H3tjQK
Current Alzheimer Research 15, Issue 5
https://bit.ly/2H1VH5E
Current Diabetes Reviews 14, Issue 2
https://bit.ly/2H3Vue2
Journal: Current Cardiology Reviews
Author(s):Chayakrit Krittanawong*, Tao Sun, Eyal Herzog
Opinion Statements: Cardiovascular diseases (CVDs) encompass a range of conditions extending from congenital heart disease to acute coronary syndrome most of which are heterogenous in nature and some of them are multiple genetic loci. However, the pathogenesis of most CVDs remains incompletely understood. The advance in genome-editing technologies, an engineering process of DNA sequences at precise genomic locations, has enabled a new paradigm that human genome can be precisely modified to achieve a therapeutic effect. Genome-editing includes the correction of genetic variants that cause disease, the addition of therapeutic genes to specific sites in the genomic locations, and the removal of deleterious genes or genome sequences. Site-specific genome engineering can be used as nucleases (known as molecular scissors) including zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) systems to provide remarkable opportunities for developing novel therapies in cardiovascular clinical care. Here we discuss genetic polymorphisms and mechanistic insights in CVDs with an emphasis on the impact of genome-editing technologies. The current challenges and future prospects for genomeediting technologies in cardiovascular medicine are also discussed.
Read more here: http://www.eurekaselect.com/154700
Combinatorial Chemistry & High Throughput Screening 20-6
Technology Transfer and Entrepreneurship 4-2
Current Organic Chemistry 21-20
Current Cardiology Reviews 13-4
Protein & Peptide Letters 24-8
Current Medicinal Chemistry 24-30
Current Medicinal Chemistry 24-31
Current Drug Discovery Technologies 14-4
Current Medicinal Chemistry 24-32
Current Alzheimer Research 14-12
Current Pharmaceutical Design 23-27
World Heart Day is to spread awareness about heart disease and stroke prevention. The World Heart Federation have found that heart disease and strokes are the world’s leading cause of death, killing 17.1 million people every year – that’s more than victims of cancer, HIV and AIDS and malaria.
Overeating, lack of exercise, unhealthy diets and high blood pressure, cholesterol and glucose levels are all factors which can trigger heart disease and threaten our own lives, and those of loved ones. Heart Day was set up to drive home the message that heart problems can be prevented.
Bentham Science publishes very important research related to this day in the following journals:
Cardiovascular & Hematological Agents in Medicinal Chemistry
To Avail 20% Discount on related eBooks, kindly visit: https://ebooks.benthamscience.com/
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