New Issue :: Current Drug Metabolism 18, Issue 3

Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews and guest edited issues in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation, recent developments for the identification of drug metabolites, adducts and preclinical and clinical summaries of marketed drugs.

Articles from the journal Current Drug Metabolism 18, Issue 3:

• Status Epilepticus: An Overview
• Toxicities of Receptor Tyrosine Kinase Inhibitors in Cancer Pharmacotherapy: Management with Clinical Pharmacology
• Insight to Pharmacokinetics of TKIs: Optimizing Practical Guidelines for Individualized Therapy
• The Physiological/Pathophysiological Significance of Vitamin D in Cancer, Cardiovascular Disorders and Beyond
• Effects of Thyroid Hormones and their Metabolites on Learning and Memory in Normal and Pathological Conditions
• Reduction of Doxorubicin-Induced Cardiotoxicity Using Nanocarriers: A Review

               For details on the articles, please visit this link :: http://bit.ly/2rM5ccL

 

 

Upcoming Thematic Issue – Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases & amp – Current Drug Metabolism

http://benthamscience.com/journals/current-drug-metabolism/special-issues/#top

Testimonial by Roberto Mandrioli!

Contributed Article: Metabolism of Drugs Used in the Therapy of Seizures: An Analytical Point of View. Part 1

Upcoming Thematic Issue – Drug Pharmacogenomics and Pharmacokinetics(PK)- Pharmacodynamics(PD)

http://www.eurekaselect.com/592/journal/current-drug-metabolism

New Issue :: Current Drug Metabolism 18, Issue 2

Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews and guest edited issues in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation, recent developments for the identification of drug metabolites, adducts and preclinical and clinical summaries of marketed drugs.

Articles from the journal Current Drug Metabolism 18, Issue 2:

• Editorial: Frontier View on Drug Discoveries for Different Diseases – Part II
• Phage Display Technique: A Novel Medicinal Approach to Overcome An tibiotic Resistance by Using Peptide-Based Inhibitors Against β-Lactamases
• A Current Perspective on the Inhibition of Cholinesterase by Natural and Synthetic Inhibitors
• Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders
• A Review on Nano-Antimicrobials: Metal Nanoparticles, Methods and Mechanisms
• Nanoparticles as a Carrier System for Drug Delivery Across Blood Brain Barrier
• Potential of Plant Alkaloids as Antipyretic Drugs of Future
• Sonication-Assisted Nanoprecipitation in Drug Delivery
• Challenges Related to Glycemic Control in Type 2 Diabetes Mellitus Patients
• Glycosides as Possible Lead Antimalarial in New Drug Discovery: Future Perspectives

For details on the articles, please visit this link :: http://bit.ly/2oZXgrl

Upcoming Thematic Issue – Topical Collection on Major Psychosis: Current findings on Drug Metabolism

http://benthamscience.com/journals/current-drug-metabolism/

Upcoming Thematic Issue – Traditional Systems of Medicine and Phytotherapy in Neurological Disorders

http://benthamscience.com/journals/current-drug-metabolism/

Article by Disease – “Brain Aging and Disorders of the Central Nervous System: Kynurenines and Drug Metabolism”

Article by Disease on “Metabolic Disorders”

Abstract:

Introduction: The kynurenine pathway includes several neuroactive compounds, including kynurenic acid, picolinic acid, 3-hydroxykynurenine and quinolinic acid. The enzymatic cascade of the kynurenine pathway is tightly connected with the immune system, and may provide a link between the immune system and neurotransmission.

Main Areas Covered: Alterations in this cascade are associated with neurodegenerative, neurocognitive, autoimmune and psychiatric disorders, such as Parkinson’s disease, Huntington’s disease, Alzheimer’s disease, multiple sclerosis, amyotrophic lateral sclerosis, migraine or schizophrenia.

Highlights: This review highlights the alterations in this metabolic pathway in the physiological aging process and in different disorders. A survey is also presented of therapeutic possibilities of influencing this metabolic route, which can be achieved through the use of synthetic kynurenic acid analogues, enzyme inhibitors or even nanotechnology.

Read more: http://www.eurekaselect.com/node/138027/article 

Upcoming Thematic Issue – Recent Development of Drug Delivery systems for improving Bioavailability and Pharmacokinetics

http://www.eurekaselect.com/592/journal/current-drug-metabolism

SMI EVENT – 12th Annual ADMET!

The SMi Group is proud to announce the return of the 12th annual ADMET conference taking place in London on the 12th – 13th June 2017.

Join our expert speaker panel at the 12th annual ADMET conference for yet another successful run! Presenting new developments, case studies and challenges in the areas of DMPK. PBPK, PKPD, in vivo/ in vitro/ in silico, transporters, hazards and safety assessment, ADMET modelling and many more!

This event will explore ADMET technologies which determine properties of a drug candidate in the preclinical stage of drug discovery, structure based prediction of ADME properties, PK/PD modelling to validate drug targets and toxicity and many more.

Visit the website for further details at http://www.admet-event.com/asd or contact at kwilliams@smi-online.co.uk

Journal: Current Drug Metabolism

EBook: Frontiers in Drug Design and Discovery, Volume 5