MOST ACCESSED ARTICLE – Genome-wide Discovery of Circular RNAs in the Leaf and Seedling Tissues of Arabidopsis Thaliana – Current Genomics

Journal: Current Genomics

Author(s): Yongchao Dou, Shengjun Li, Weilong Yang, Kan Liu, Qian Du, Guodong Ren*, Bin Yu*, Chi Zhang 

Graphical Abstract:

 

Abstract:

Background: Recently, identification and functional studies of circular RNAs, a type of non-coding RNAs arising from a ligation of 3’ and 5’ ends of a linear RNA molecule, were conducted in mammalian cells with the development of RNA-seq technology.

Method: Since compared with animals, studies on circular RNAs in plants are less thorough, a genome- wide identification of circular RNA candidates in Arabidopsis was conducted with our own developed bioinformatics tool to several existing RNA-seq datasets specifically for non-coding RNAs.

Results: A total of 164 circular RNA candidates were identified from RNA-seq data, and 4 circular RNA transcripts, including both exonic and intronic circular RNAs, were experimentally validated. Interestingly, our results show that circular RNA transcripts are enriched in the photosynthesis system for the leaf tissue and correlated to the higher expression levels of their parent genes. Sixteen out of all 40 genes that have circular RNA candidates are related to the photosynthesis system, and out of the total 146 exonic circular RNA candidates, 63 are found in chloroplast.
To access the article, please visit: http://www.eurekaselect.com/150708/article

 

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Applied Clinical Research, Clinical Trials and Regulatory Affairs Volume 4, Issue 3
http://bit.ly/2DhTkZM

Current Genomics Volume 19, Issue 2
http://bit.ly/2DBv0Qo

Current Immunology Reviews Volume 13, Issue 2
http://bit.ly/2ELHq7r

recent-issues

MOST ACCESSED ARTICLE – Genome-wide Discovery of Circular RNAs in the Leaf and Seedling Tissues of Arabidopsis Thaliana – Current Genomics

Journal: Current Genomics

Author(s): Yongchao Dou, Shengjun Li, Weilong Yang, Kan Liu, Qian Du, Guodong Ren*, Bin Yu*, Chi Zhang 

Graphical Abstract:

 

Abstract:

Background: Recently, identification and functional studies of circular RNAs, a type of non-coding RNAs arising from a ligation of 3’ and 5’ ends of a linear RNA molecule, were conducted in mammalian cells with the development of RNA-seq technology.

Method: Since compared with animals, studies on circular RNAs in plants are less thorough, a genome- wide identification of circular RNA candidates in Arabidopsis was conducted with our own developed bioinformatics tool to several existing RNA-seq datasets specifically for non-coding RNAs.
Results: A total of 164 circular RNA candidates were identified from RNA-seq data, and 4 circular RNA transcripts, including both exonic and intronic circular RNAs, were experimentally validated. Interestingly, our results show that circular RNA transcripts are enriched in the photosynthesis system for the leaf tissue and correlated to the higher expression levels of their parent genes. Sixteen out of all 40 genes that have circular RNA candidates are related to the photosynthesis system, and out of the total 146 exonic circular RNA candidates, 63 are found in chloroplast.
To access the article, please visit: http://www.eurekaselect.com/150708

 

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Genomics  18-6

http://bit.ly/2ALJWc1

Letters in Organic Chemistry 14-9

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Anti-Cancer Agents in Medicinal Chemistry 17-10

http://bit.ly/2z7DC2k

Recent Patents on Anti-Infective Drug Discovery 12-1

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Current Organic Chemistry 21-18

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Letters in Drug Design & Discovery 14-11

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WISHING A VERY HAPPY BIRTHDAY TO Dr. C. Christian Neri!

Dr C.CHRISTIAN nERI

Dr. C. Christian Neri

EDITOR-IN-CHIEF: CURRENT GENOMICS

Institute of Biology Paris-Seine
CNRS UMR 8256 and UPMC
Paris, 75005
France

Testimonial by Gui-Hua Lu!

Gui-Hua Lu

Contributed Article: “Impact of Glyphosate on the Rhizosphere Microbial Communities of An EPSPS-Transgenic Soybean Line ZUTS31 by Metagenome Sequencing

Highlighted Article – Detecting Chromosome Condensation Defects in Gulf War Illness Patients – Current Genomics

CG-Articles_18-6-Henry Heng

http://benthamscience.com/journals/current-genomics/#top

Upcoming Thematic Issue – Genomic and Epigenomics of Tumor and Aging Cells – Current Genomics

CG-THEMATIC FLYER -Gjumrakch Aliev, MD&PhD

http://benthamscience.com/journals/current-genomics/special-issues/

Highlighted Article – Genomics of Metal Stress-Mediated Signalling and Plant Adaptive Responses in Reference to Phytohormones – Current Genomics

CG-Articles_18-6-Sudhakar Srivastava

http://www.eurekaselect.com/153012/article

Highlighted Article Flyer for the journal “Current Genomics”

CG-Articles_18-6-Juan C. Carril

http://www.eurekaselect.com/101889/article