WISHING A VERY HAPPY BIRTHDAY TO DR. GYÖRGY KEGLEVICH!

Dr. Gyorgy Keglevich

DR. GYÖRGY KEGLEVICH

EDITOR-IN-CHIEF: CURRENT ORGANIC CHEMISTRY & CURRENT GREEN CHEMISTRY

DEPARTMENT OF ORGANIC CHEMICAL TECHNOLOGY,

BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS,

 BUDAPEST, HUNGARY

UPCOMING THEMATIC ISSUE – RECENT ADVANCES IN THE HETEROCYCLES – CURRENT ORGANIC CHEMISTRY

COC-THEMATIC FLYER-Wail Al Zoubi

https://benthamscience.com/journals/current-organic-chemistry/#top

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Psychiatry Reviews13-3

http://bit.ly/2BsgWHK

Anti-Cancer Agents in Medicinal Chemistry 17-11

http://bit.ly/2B9JYyY

Current Medicinal Chemistry 24 -36

http://bit.ly/2CWxoR8

Current Organic Chemistry 21-23

http://bit.ly/2oAC1Nr

Current Organic Synthesis 14 -7

http://bit.ly/2CTfgr8

Current Pharmaceutical Design 23-30

http://bit.ly/2oAUXvo

Current Drug Targets  18-16

http://bit.ly/2jbzp3c

Current Medicinal Chemistry 24 -37

http://bit.ly/2CUDmSr

Current Genomics 19 -1

http://bit.ly/2BaL5hR

Current Pharmaceutical Design 23 -31

http://bit.ly/2ARCYm4

recent-issues

NEW ISSUE :: CURRENT ORGANIC CHEMISTRY 21, ISSUE 24

Current Organic Chemistry aims to provide in-depth reviews on the current progress in the fields of asymmetric synthesis, organo-metallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry and analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic chemistry.

coc

Articles from the journal Current Organic Chemistry 21-24:

For details on the articles, please visit this link: http://bit.ly/2CjF3LO

 

 

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Recent Patents on Inflammation & Allergy Drug Discovery 11-2

http://bit.ly/2C7S8si

Current Rheumatology Reviews 13-3

http://bit.ly/2lou1KD

Current Bioinformatics 12-6

http://bit.ly/2EbgFds

Current Drug Metabolism 18-9

http://bit.ly/2C72usv

Current Stem Cell Research & Therapy 13-1

http://bit.ly/2lp9Bky

Current Organic Chemistry 21-25

http://bit.ly/2CfRqIO

Current Smart Materials 2-2

http://bit.ly/2DsWNRJ

recent-issues

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Pharmaceutical Biotechnology 18-8

http://bit.ly/2zjUmBQ

Current Biotechnology 6-4

http://bit.ly/2B7X2EZ

Current Neuropharmacology 15-8

http://bit.ly/2BB1nAd

Current Cancer Therapy Reviews 13-2

http://bit.ly/2kIQDp0

Current Pharmaceutical Design 23-29

http://bit.ly/2BFwmLq

Mini-Reviews in Organic Chemistry 14-6

http://bit.ly/2CyKMKf

Current Organic Chemistry 21-22

http://bit.ly/2ySgZcR

Current Medical Imaging Reviews 13-4

http://bit.ly/2B7l0jP

Current Proteomics 14-4

http://bit.ly/2BahSU8

Endocrine, Metabolic & Immune Disorders – Drug Targets 17-4

http://bit.ly/2AUG8W8

recent-issues

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Recent Patents on Mechanical Engineering 10-3

http://bit.ly/2knILJ8

Letters in Drug Design & Discovery 14-12

http://bit.ly/2l1EsHw

Current Topics in Medicinal Chemistry 17-27

http://bit.ly/2B68pw9

Recent Innovations in Chemical Engineering 10-1

http://bit.ly/2B8ffRD

Current Stem Cell Research & Therapy 12-8

http://bit.ly/2yhlgGF

Current Organic Chemistry 21-21

http://bit.ly/2Adezr0

Current Pharmaceutical Design 23-28

http://bit.ly/2yhksS3

Letters in Organic Chemistry 14-10

http://bit.ly/2Aw82vy

recent-issues

OPEN ACCESS ARTICLE – Isoflavones, their Glycosides and Glycoconjugates. Synthesis and Biological Activity – Current Organic Chemistry

Journal: Current Organic Chemistry

Author(s): Wieslaw Szeja, Grzegorz Grynkiewicz, Aleksandra Rusin

Graphical Abstract:

 

Abstract:

Glycosylation of small biologically active molecules, either of natural or synthetic origin, has a profound impact on their solubility, stability, and bioactivity, making glycoconjugates attractive compounds as therapeutic agents or nutraceuticals. A large proportion of secondary metabolites, including flavonoids, occur in plants as glycosides, which adds to the molecular diversity that is much valued in medicinal chemistry studies. The subsequent growing market demand for glycosidic natural products has fueled the development of various chemical and biotechnological methods of glycosides preparation. The review gives an extensive overview of the processes of the synthesis of isoflavones and discusses recently developed major routes towards isoflavone-sugar formation processes. Special attention is given to the derivatives of genistein, the main isoflavone recognized as a useful lead in several therapeutic categories, with particular focus on anticancer drug design. The utility of chemical glycosylations as well as glycoconjugates preparation is discussed in some theoretical as well as practical aspects. Since novel approaches to chemical glycosylations and glycoconjugations are abundant and many of them proved suitable for derivatization of polyphenols a new body of evidence has emerged, indicating that sugar moiety can play a much more significant role, when attached to a pharmacophore, then being a mere “solubilizer”. In many cases, it has been demonstrated that semisynthetic glycoconjugates are much more potent cytostatic and cytotoxic agents than reference isoflavones. Moreover, the newly designed glycosides or glycoside mimics can act through different mechanisms than the parent active molecule.

Read more here: http://www.eurekaselect.com/145877

 

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Combinatorial Chemistry & High Throughput Screening 20-6

http://bit.ly/2Axrqrc

Technology Transfer and Entrepreneurship 4-2

http://bit.ly/2ngNRvs

Current Organic Chemistry 21-20

http://bit.ly/2iwN3kv

Current Cardiology Reviews 13-4

http://bit.ly/2j7t2hB

Protein & Peptide Letters 24-8

http://bit.ly/2AhTCxT

Current Medicinal Chemistry 24-30

http://bit.ly/2jzWzju

Current Medicinal Chemistry 24-31

http://bit.ly/2i5DLbg

Current Drug Discovery Technologies 14-4

http://bit.ly/2iICJC3

Current Medicinal Chemistry 24-32

http://bit.ly/2yJM1si

Current Alzheimer Research 14-12

http://bit.ly/2nlkYhA

Current Pharmaceutical Design 23-27

http://bit.ly/2AwrVlq

recent-issues

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Genomics  18-6

http://bit.ly/2ALJWc1

Letters in Organic Chemistry 14-9

http://bit.ly/2A3NE4x

Anti-Cancer Agents in Medicinal Chemistry 17-10

http://bit.ly/2z7DC2k

Recent Patents on Anti-Infective Drug Discovery 12-1

http://bit.ly/2zO2FUQ

Current Organic Chemistry 21-18

http://bit.ly/2imER31

Letters in Drug Design & Discovery 14-11

http://bit.ly/2j0qgdc

Current Pharmaceutical Design 23-26

http://bit.ly/2il5XYk

recent-issues