Editor’s Choice – The Impact of Cancer and its Treatment on the Growth and Development of the Pediatric Patient – Current Pediatric Reviews

Journal: Current Pediatric Reviews

Author(s): Sarah Brand, Joanne Wolfe, Chase Samsel.

Graphical Abstract:



Background: Cancer treatment can have profound effects on the growth and development of pediatric patients. Different models of psychosocial development and behavioral treatment approaches aid children receiving medical treatment. Providing education, anticipatory guidance, and individualized support to child and their families is a psychosocial standard.

Objective: Clarify the different models of psychosocial development and applicable psychosocial interventions to better prepare and tailor cancer treatment to pediatric patients.

Methods: Authors reviewed existing evidenced-based literature in oncology, psychology, developmental, and psychiatric while drawing on case examples and expert knowledge to illustrate the impact of cancer treatment on pediatric patients, analyze developmentally individualized needs, and describe facilitative interventions.
Result: Pediatric patients of all ages cope and adjust better to all phases of treatment when their care is delivered in a developmentally-informed and psychosocially thoughtful way.
Conclusion: Providers can comprehensively prepare their patients and families for treatment better by utilizing a psychosocially- and developmentally-informed framework while meeting individualized unique needs of patients. An integrated multidisciplinary psychosocial support team is facilitative in anticipating and meeting the needs of pediatric cancer patients and has recently become a psychosocial standard of care.

Most Accessed Article – Newborn Bilirubin Screening for Preventing Severe Hyperbilirubinemia and Bilirubin Encephalopathy – Current Pediatric Reviews

Journal: Current Pediatric Reviews

Author(s): Kalpana Bhardwaj, Tiffany Locke, Anne Biringer, Allyson Booth, Elizabeth K. Darling, Shelley Dougan, Jane Harrison, Stephen Hill, Ana Johnson, Susan Makin, Beth Potter, Thierry Lacaze-Masmonteil, Julian Little.

Graphical Abstract:



According to the 2004 American Academy of Pediatrics guideline on the management of hyperbilirubinemia, every newborn should be assessed for the risk of developing severe hyperbilirubinemia with the help of predischarge total serum bilirubin or transcutaneous bilirubin measurements and/or assessments of clinical risk factors. The aim of this rapid review is 1) to review the evidence for 1) predicting and preventing severe hyperbilirubinemia and bilirubin encephalopathy, 2) determining the efficacy of home/community treatments (home phototherapy) in the prevention of severe hyperbilirubinemia, and 3) non-invasive/transcutaneous methods for estimating serum bilirubin level. Methods: In this rapid review, studies were identified through the Medline database. The main outcomes of interest were severe hyperbilirubinemia and encephalopathy. A subset of articles was double screened and all articles were critically appraised using the SIGN and AMSTAR checklists. This review investigated if systems approach is likely to reduce the occurrence of severe hyperbilirubinemia. Results: Fifty-two studies met the inclusion criteria. Included studies assessed the association between bilirubin measurement early in neonatal life and the subsequent development of severe hyperbilirubinemia and chronic bilirubin encephalopathy/kernicterus. It was observed that, highest priority should be given to (i) universal bilirubin screening programs; (ii) implementation of community and midwife practice; (iii) outreach to communities for education of prospective parents; and (iv) development of clinical pathways to monitor, evaluate and track infants with severe hyperbilirubinemia. Conclusions: We found substantial observational evidence that severe hyperbilirubinemia can be accurately predicted and prevented through universal bilirubin screening. So far, there is no evidence of any harm.

To access the article, please visit: http://www.eurekaselect.com/149128

Highlighted Article – Insights in Developmental Coordination Disorder Marie – Current Pediatric Reviews

CPR-Articles_13-4-M`hamed Bentourkia

To access this article, please visit: http://www.eurekaselect.com/154487

Article by Disease – “Vitiligo in Children: A Birds Eye View”

Article by Disease on “Endocrine Diseases


Vitiligo in children is a distinct subset of vitiligo and differs from adult vitiligo. Characteristic features include family history of autoimmune or endocrine disease, higher incidence of segmental vitiligo, development of early or premature graying, increased incidence of autoantibodies and poor response to topical PUVA. The exact prevalence of vitiligo in children varies between 0.1-4% of the world population and seems to be higher in India than in other countries and it occurs more frequently in females. Around 12% to 35% of pediatric vitiligo patients have family members with the disease. The most common type of vitiligo in pediatric patients is vitiligo vulgaris, representing 78% of cases. The most commonly associated autoimmune disease is thyroiditis. Phototherapy and topical corticosteroids are the most commonly used treatments for adult vitiligo but are less useful in the pediatric population.

Read more: http://www.eurekaselect.com/node/138295/article

World Autism Awareness Day!


World Autism Awareness Day observed on the 2nd of April, aims to increase awareness about people, especially children, with autism. Autism is a complex developmental disability; signs typically appear during early childhood and affect a person’s ability to communicate, and interact with others. There is no known single cause of autism, but increased awareness and early diagnosis/intervention and access to appropriate services/supports lead to significantly improved outcomes.

Bentham Science publishes research papers that present new studies related to this particular disease. Find the latest studies in the following journals:

Current Pediatric Reviews

CNS & Neurological Disorders – Drug Targets

World Down Syndrome Day 2017!


World Down Syndrome Day (WDSD) is meant to spread global awareness of Down Syndrome which is caused by triplication (trisomy) of the 21st chromosome. Down syndrome is a rare chromosomal mutation that has has a significant impact on the affected person as well as the people around them. Being a genetic disorder, Down syndrome is observed in populations regardless of racial, gender and socio-economic lines.

Bentham Science journals publish papers that present research on this particular disease. Here are some articles covering Down Syndrome:

To view more articles, please visit: Current Pediatric Reviews

Article by Disease – “Clinico-Hematological Features and Management Outcome in Neonatal Malaria: A Nine Years Analysis from North India”

Article by Disease on “Pediatrics and Neonatology”



Background: Malaria is an important cause of death and illness in children worldwide. Most cases of neonatal malaria are misdiagnosed because of lack of specific symptoms and general lack of awareness. Nothing much is known in literature about the hematological changes during malaria infection and outcome of disease in neonates. Neonatal malaria is an underdiagnosed entity. So this hospital based observational study aims to assess diagnostic features of neonatal malaria.

Methods: From August 2004 to August 2013, information of all slide positive for malaria cases aged 0 to 28 days admitted to our pediatric hospital was collected and analysed.Results: 28 slide positive cases of neonatal malaria were studied, four out of them were congenital malaria. Fever (93%) was the most common symptom followed by pallor (72%) and diarrhoea (50%). We also found respiratory distress in four (14%) cases. Apart from anemia and atypical lymphocytosis, We also found thrombocytopenia and low hematocrit, MCV and RBC count. Two cases with bleeding manifestations expired during course of treatment.Discussion: Malaria in the first few months of life can simulate transplacentally or postnatally acquired infection such as TORCH, syphilis, neonatal hepatitis and septicemia all having an important symptom complex of fever jaundice, hepatosplenomegaly and anemia. Although in our cases clinical presentation has been similar to septicemia but culture of blood, CSF and urine were sterile. The dilemma of distinguishing neonatal malaria alone versus neonatal sepsis or both existing does not seem to be easily resolved by the use of clinical features alone. The laboratory diagnosis of parasitemia in neonates require special attention in Giemsa staining as well as the technical skill involved in malaria microscopy because parasite densities are low. So high degree of suspicion is needed to diagnose malaria in newborns presenting with fever and anemia.

Read more: http://benthamscience.com/journals/current-pediatric-reviews/volume/12/issue/4/page/286/

New Issue :: Current Pediatric Reviews 12, Issue 4

Current Pediatric Reviews publishes frontier reviews, drug clinical trial studies and guest edited thematic issues on all the latest advances in pediatric medicine. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in pediatric medicine.


Articles from the journal Current Pediatric Reviews 12, Issue 4:

               For details on the articles, please visit this link :: http://bit.ly/2j91NSa

Recently published issues in the journals of Bentham Science

Current Physical Chemistry, 6 Issue 3


Current Organic Chemistry , 20 Issue 24


Innovations in Corrosion and Materials Science , 6 Issue 2


Current Molecular Pharmacology , 9 Issue 3


International Journal of Sensors Wireless Communications and Control, 6 Issue 2


Nanoscience & Nanotechnology-Asia, 6 Issue 2


Current Topics in Medicinal Chemistry, 16 Issue 27


Current Pharmaceutical Design, 22 Issue 30


Current Medicinal Chemistry, 23 Issue 26


Current Pediatric Reviews, 12 Issue 3



New Issues of various Bentham Science Journals

Current Analytical Chemistry, 12 Issue 3


Current Pediatric Reviews, 12 Issue 2


Current Pharmaceutical Design, 22 Issue 18


CNS & Neurological Disorders – Drug Targets, 15 Issue 5


Current Medicinal Chemistry, 23 Issue 13


Mini-Reviews in Organic Chemistry, 13 Issue 2


Infectious Disorders – Drug Targets, 16 Issue 1


Medicinal Chemistry, 12 Issue 4


Current Stem Cell Research & Therapy, 11 Issue 5


Protein & Peptide Letters, 23 Issue 6


Recent Issues