Wishing you a very Happy Birthday | Dr. Allen B. Retiz

 

Dr. Allen B. Retiz serves as the Editor-in-Chief of the Journal “Current Topics in Medicinal Chemistry“

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

New Issue | Current Medicinal Chemistry; Volume 27 Issue 4

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

 

Articles from the journal: Current Medicinal Chemistry; Volume 27 Issue 4

• Radiochemistry: A Useful Tool in the Ophthalmic Drug Discovery
• Tear Inflammatory Molecules in Contact Lens Wearers: A Literature Review
• Anti-VEGF Treatment and Response in Age-related Macular Degeneration: Disease’s Susceptibility, Pharmacogenetics and Pharmacokinetics
• Trojan Microparticles Potential for Ophthalmic Drug Delivery
• Pharmacological Advances in the Treatment of Age-related Macular Degeneration
• Phytochemical-Mediated Glioma Targeted Treatment: Drug Resistance and Novel Delivery Systems
• Tuberculosis – Present Medication and Therapeutic Prospects

For details on the articles, please visit this link: http://www.eurekaselect.com/node/602/current-medicinal-chemistry/issue/27/2698/4/9716

Animated Abstract | A Possible Modulation Mechanism of Intramolecular and Intermolecular Interactions for NCAM Polysialylation and Cell Migration

 

Journal Name: Current Topics in Medicinal Chemistry

Author(s): Bo Lu, Xue-Hui Liu, Si-Ming Liao, Zhi-Long Lu, Dong Chen, Frederic A. Troy II, Ri-Bo Huang*, Guo-Ping Zhou*.

 

Graphical Abstract:

 

Animated Abstract:

 

 

 

Abstract:

Polysialic acid (polySia) is a novel glycan that posttranslationally modifies neural cell adhesion molecules (NCAMs) in mammalian cells. Up-regulation of polySia-NCAM expression or NCAM polysialylation is associated with tumor cell migration and progression in many metastatic cancers and neurocognition. It has been known that two highly homologous mammalian polysialyltransferases (polySTs), ST8Sia II (STX) and ST8Sia IV (PST), can catalyze polysialylation of NCAM, and two polybasic domains, polybasic region (PBR) and polysialyltransferase domain (PSTD) in polySTs play key roles in affecting polyST activity or NCAM polysialylation. However, the molecular mechanisms of NCAM polysialylation and cell migration are still not entirely clear. In this minireview, the recent research results about the intermolecular interactions between the PBR and NCAM, the PSTD and cytidine monophosphate-sialic acid (CMP-Sia), the PSTD and polySia, and as well as the intramolecular interaction between the PBR and the PSTD within the polyST, are summarized. Based on these cooperative interactions, we have built a novel model of NCAM polysialylation and cell migration mechanisms, which may be helpful to design and develop new polysialyltransferase inhibitors. To know more about our Animated Abstract, please visit: http://www.eurekaselect.com/175822/article

New Issue | Current Topics in Medicinal Chemistry; Volume 19 Issue 31

 

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

 

Articles from the journal: Current Topics in Medicinal Chemistry; Volume 19 Issue 31

• Salivary mir-27b Expression in Oral Lichen Planus Patients: A Series of Cases and a Narrative Review of Literature
• The Cooperative Effect between Polybasic Region (PBR) and Polysialyltransferase Domain (PSTD) within Tumor-Target Polysialyltranseferase ST8Sia II
• Mechanism and Development of Modern General Anesthetics
• Medicinal Value and Potential Therapeutic Mechanisms of Gynostemma pentaphyllum (Thunb.) Makino and Its Derivatives: An Overview
• Marine Actinomycetes-derived Natural Products
• Progress in the Mechanism and Clinical Application of Cilostazol

 

 

 

For details on the articles, please visit this link: http://www.eurekaselect.com/node/615/current-topics-in-medicinal-chemistry/issue/19/2599/31/9575

New Issue | Current Topics in Medicinal Chemistry; Volume 19 Issue 25

 

 

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

 

Articles from the journal: Current Topics in Medicinal Chemistry; Volume 19 Issue 25

• A Possible Modulation Mechanism of Intramolecular and Intermolecular Interactions for NCAM Polysialylation and Cell Migration
• Impacts of Pseudo Amino Acid Components and 5-steps Rule to Proteomics and Proteome Analysis
• Identifying Cancer Targets Based on Machine Learning Methods via Chou’s 5-steps Rule and General Pseudo Components
• A Study for Therapeutic Treatment against Parkinson’s Disease via Chou’s 5-steps Rule
• Recent Advances in Ginsenosides as Potential Therapeutics Against Breast Cancer
• Biological Production of (S)-acetoin: A State-of-the-Art Review
• Cyclodextrin Inclusion of Medicinal Compounds for Enhancement of their Physicochemical and Biopharmaceutical Properties

For details on the articles, please visit this link: http://www.eurekaselect.com/node/615/current-topics-in-medicinal-chemistry/issue/19/2599/25/9462

Press Release | Bentham Science journals improve impact factor ratings in 2019

Here are the top 10 high impact factor journals published by Bentham Science

 

The latest edition of Journal Citation Reports® 2019 has been published recently, and according to the report, Bentham Science Publishers (BSP) journals have significantly improved their Impact Factors. Current Neuropharmacology is leading the list again with the highest impact factor (IF: 4.568) among all the journals. In total, 40 BSP journals have received Impact Factor ratings this year. The latest results in the JCR 2019 reflect the high quality of research published by Bentham Science.

Journal Citation Reports (JCR) is an annual publication by Clarivate Analytics. JCR has been integrated with the Web of Science and is accessible from the Web of Science-Core Collections. Its purpose is to offer a systematic means to critically evaluate the world’s leading journals, with quantifiable, statistical information based on citation data.

Bentham Science publishes over 100 print & online scholarly subscription journals and books. Learn more about Bentham Science here: http://www.benthamscience.com

 

Read full press release to find out more at: https://www.eurekalert.org/pub_releases/2019-06/bsp-bsl062019.php

Become an Editorial Board Member (EBM) | Current Medicinal Chemistry

 

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Abstracted and Indexed in:

• Science Citation Index®
• Journal Citation Reports/Science Edition
• InCites
• Science Citation Index Expanded
• Index to Scientific Reviews®
• Biochemistry and Biophysics Citation Index®
• Current Contents® – Life Sciences
• Research Alert
• BIOSIS
• BIOSIS Previews
• BIOSIS Reviews Reports and Meetings
• Prous Science Integrity®
• MEDLINE/PubMed/Index Medicus
• Scopus
• EMBASE/Excerpta Medica
• Chemical Abstracts Service/SciFinder
• ProQuest
• ChemWeb
• Google Scholar
• BIOBASE
• Reference Update
• PubsHub
• Index Copernicus
• MediaFinder®-Standard Periodical Directory
• Genamics JournalSeek
• J-Gate
• CNKI Scholar
• Suweco CZ
• TOC Premier
• EBSCO
• British Library
• Ulrich’s Periodicals Directory
• JournalTOCs

The Journal Current Medicinal Chemistry is interested in appointing active Editorial Board Member  on the Journal’s Board. If you are working in the mentioned field of the journal and are interested in becoming an Editorial Board Member, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field of interest, please feel free to recommend suitable colleagues for the said position and, if possible, send us their CV along with their list of publications. Mention in the subject line, the field of interest and send your CV at hermain@benthamscience.net and CC faizan@benthamscience.net

 

 

New Issue | Current Topics in Medicinal Chemistry; Volume: 19, Issue: 6

 

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

 

 

Articles from the journal: Current Topics in Medicinal Chemistry; Volume: 19, Issue: 6

• How Cancer Cells Resist Chemotherapy: Design and Development of Drugs Targeting Protein-Protein Interactions
• Algorithmic and Stochastic Representations of Gene Regulatory Networks and Protein-Protein Interactions
• Quantum Molecular Dynamics, Topological, Group Theoretical and Graph Theoretical Studies of Protein-Protein Interactions
• Protein/ Hormone Based Nanoparticles as Carriers for Drugs Targeting Protein-Protein Interactions
• Influence of Amino Acid Mutations and Small Molecules on Targeted Inhibition of Proteins Involved in Cancer
• Targeting Kinase Interaction Networks: A New Paradigm in PPI Based Design of Kinase Inhibitors

 

For details on the articles, please visit this link: http://www.eurekaselect.com/node/615/current-topics-in-medicinal-chemistry/issue/19/2599/6/9078

 

 

 

New Issue | Current Topics in Medicinal Chemistry 19-5

 

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

 

 

Articles from the journal Current Topics in Medicinal Chemistry Volume 19, Issue 5:

• Trends in Enzyme Inhibition and Activation in Drug Design – Part II
• Prediction of Drug-Drug Interactions Related to Inhibition or Induction of Drug-Metabolizing Enzymes
• Mycobacterial tuberculosis Enzyme Targets and their Inhibitors
• Design, Synthesis, Evaluation of Antimicrobial Activity and Docking Studies of New Thiazole-based Chalcones
• Synthesis and In Vitro Enzymatic Studies of New 3-Aryldiazenyl Indoles as Promising Helicobacter pylori IMPDH Inhibitors
• Docking Assisted Prediction and Biological Evaluation of Sideritis L. Components with PTP1b Inhibitory Action and Probable Anti-Diabetic Properties

For more details on the article, please visit: https://bit.ly/2PiwVza

New Issues of various Bentham Science Journals

 

1. Mini-Reviews in Medicinal Chemistry, Vol: 18, Issue: 16

https://bit.ly/2qCXROI

2. Mini-Reviews in Medicinal Chemistry, Vol: 18, Issue: 17

https://bit.ly/2qBcaDd

3. Current Drug Targets, Vol: 19, Issue: 13

https://bit.ly/2QttYLL

4. Current Drug Metabolism, Vol: 19, Issue: 10

https://bit.ly/2qAdypw

5. Current Cancer Drug Targets, Vol: 18, Issue: 8

https://bit.ly/2z3e6sN

6. Current Pharmaceutical Analysis, Vol: 14, Issue: 6

https://bit.ly/2PNXYVE

7. The Natural Products Journal, Vol: 8, Issue: 3

https://bit.ly/2yYGJY6

8. Current Organocatalysis, Vol: 5, Issue: 2

https://bit.ly/2RKY65t

9. Current Drug Safety, Vol: 13, Issue: 3

https://bit.ly/2OvKMjC

10. Current Topics in Medicinal Chemistry, Vol: 18, Issue: 12

https://bit.ly/2D9ecSA