Article by Disease | An Overview of Targeted Alpha Therapy with 225Actinium and 213Bismuth

Bentham Oncology Collection | Oncology | Bladder Cancer 

 

Graphical Abstract:

 

Abstract:

Background: Recent reports of the remarkable therapeutic efficacy of 225Ac-labeled PSMA- 617 for therapy of metastatic castration-resistant prostate cancer have underlined the clinical potential of targeted alpha therapy.

Objective and Conclusion: This review describes methods for the production of 225Ac and its daughter nuclide 213Bi and summarizes the current clinical experience with both alpha emitters with particular focus on recent studies of targeted alpha therapy of bladder cancer, brain tumors, neuroendocrine tumors and prostate cancer.

 

 

Find out more at: http://www.eurekaselect.com/node/161764/article

Article by Disease | Ultrasonography Fused with PET-CT Hybrid Imaging

Bentham Oncology Collection | Oncology | Anal Cancer

Abstract:

We present a method with fusion of images of three modalities 18F-FDG PET, CT, and 3-D ultrasound (US) applied to imaging of the anal canal and the rectum. To obtain comparable geometries in the three imaging modalities, a plexiglas rod, with the same dimensions as the US transducer, is placed in the anal canal prior to the PET-CT examination. The method is based on manual co-registration of PET-CT images and 3-D US images. The three-modality imaging of the rectum-anal canal may become useful as a supplement to conventional imaging in the external radiation therapy in the treatment of anal cancer, where the precise delineation of a tumor is crucial to avoid damage from radiation therapy to the healthy tissue surrounding it. The technique is still in a phase of development, and the demands for integration different company software systems are significant before commercial application. Three-modality imaging may also be used in certain other diagnostic or therapeutic fields.

 

 

Browse the article details at: http://www.eurekaselect.com/node/74230/article

UPCOMING THEMATIC ISSUE – Stromal: Hemopoietic Complex and its role in the development of Malignant Diseases of the Blood System – CURRENT CANCER THERAPY REVIEWS

https://benthamscience.com/journals/current-cancer-therapy-reviews/special-issues/

Lighting Times in Hospitals Affect Patients’ Health

Human beings are used to a cycle of light timings with light in the day and dark in the night. Accordingly, our mind and body feel active in daytime and laze afterwards. When we are exposed to light in inappropriate hours we tend to get irritated and find it hard to respond properly. Same phenomenon can get exacerbated if we are ill, as our body and mind is already fighting diseases and cannot bear extra agony. Yet this is a common sight in hospitals, medical centers and nursing homes that they are shining bright twenty-four hours – especially in the I.C.U. and other sensitive sections.

It has been ignored mostly but now researchers are paying attention to the potential ill-effects this untimely lighting has on our circadian rhythm, i.e. our biological clock. Scientists from University of Colorado suggest that if the hospitals, medical centers and the likes control their light intensity, duration and sunlight exposure than they may help patients recover quicker than otherwise. This subject is wide and welcoming for further research that can help improve the conditions.

Find out more on this topic from the research article, Entrainment of the Human Circadian Clock to the Light-Dark Cycle and its Impact on Patients in the ICU and Nursing Home Settings.

4th Microbiome R&D and Business Collaboration Forum: Europe

Global Engage is pleased to announce the 4^th Microbiome R&D and Business Collaboration Forum: Europe which will be held on 3-4 April 2017.

For more details visit: http://www.global-engage.com/event/microbiota/

4th Microbiome R&D and Business Collaboration Forum: Europe

Global Engage is pleased to announce the 4^th Microbiome R&D and Business Collaboration Forum: Europe which will be held on 3-4 April 2017.

For more details visit: http://www.globalengage.co.uk/microbiota.html

Zika Virus Outbreak!

What is ZIKA Virus?

Zika virus disease (Zika) is a disease caused by the Zika virus, which is spread to people primarily through the bite of an infected Aedes species mosquito.

What are the Symptoms?

The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting for several days to a week after being bitten by an infected mosquito. People usually don’t get sick enough to go to the hospital, and they very rarely die of Zika. For this reason, many people might not realize they have been infected. However, Zika virus infection during pregnancy can cause a serious birth defect called microcephaly, as well as other severe fetal brain defects. Once a person has been infected, he or she is likely to be protected from future infections.

ZIKA Discovery

Zika virus was first discovered in 1947 and is named after the Zika Forest in Uganda. In 1952, the first human cases of Zika were detected and since then, outbreaks of Zika have been reported in tropical Africa, Southeast Asia, and the Pacific Islands.

Before 2007, at least 14 cases of Zika had been documented, although other cases were likely to have occurred and were not reported. Because the symptoms of Zika are similar to those of many other diseases, many cases may not have been recognized.

In May 2015, the Pan American Health Organization (PAHO) issued an alert regarding the first confirmed Zika virus infection in Brazil. On February 1, 2016, the World Health Organization (WHO) declared Zika virus a Public Health Emergency of International Concern (PHEIC). Local transmission has been reported in many other countries and territories. Zika virus will likely continue to spread to new areas.

USA initiative for ZIKA Control

The US President Obama is calling on congress to fight the Zika virus by providing $1.8 Billion in Emergency funds to rapidly expand mosquito control programs, accelerate vaccine research and diagnostic development, and educate health providers, women and others about the disease to help Zika-affected countries for better control on transmission.

Spread the knowledge to prevent Zika virus!

Brand New eBook Published:

“The Medical Lives of History’s Famous People”

About the eBook:
The Medical Lives of History`s Famous People highlights the effects of various diseases on the public lives of famous individuals in history. The contents of this book include chapters on the historical facts concerning Babe Ruth`s heroic battle with nasopharyngeal carcinoma, the oral cancer affecting Sigmund Freud, Celiac disease (the cause of president John F. Kennedy`s lifelong medical travails), porphyria (the condition afflicting King George), Hemophilia (the ‘Royal disease’) and much more.
The Medical Lives of History`s Famous People is an interesting and valuable resource for general readers and researchers, alike, seeking historical information about several medical ailments.

About the Author:
William J. Maloney has been practicing dentistry for over 22 years. He is a clinical associate professor at New York University College of Dentistry where he was presented with the Student National Dental Association faculty appreciation award. He has published extensively in many peer-reviewed journals. His research interests include the history of medicine and dentistry, oral and dental manifestations of systemic diseases, forensic dentistry, and the oral and dental significance of illicit and prescription drug abuse and misuse.

For more details about this eBook, visit:http://ebooks.benthamscience.com/book/9781608059362/

#historyofmedicine
#famouspeople

EBOLA IS TREATABLE!

New York Times published a news not more than a miracle, as two American #Ebola patients gets a green single from Atlanta hospital after recovery!