Press Release | Endothelial regenerative capacity and aging: Influence of diet, exercise and obesity

The endothelium plays an important role in cardiovascular regulation, from blood flow to platelet aggregation, immune cell infiltration and demargination. Endothelium dysfunction inevitably leads to the onset and progression of cardiovascular disease (CVD). The aging endothelium displays significant changes in function, such as reduced vasomotor functions and reduced angiogenic capabilities. This may be partially due to increased levels of oxidative stress and reduced endothelial cell turnover.

Endothelial Progenitor Cells (EPCs) are circulating angiogenic cells which play an important role in maintaining endothelial health and function. EPCs maintain endothelial health and function by supporting cell proliferation or by incorporation into vasculature and differentiation into mature endothelial cells. However, EPCs are reduced in number with age, and this reduction may also contribute to elevated CVD risk in aging populations. Lifestyle factors such as exercise, physical activity obesity, and dietary intake of omega-3 polyunsaturated fatty acids, nitrates, and antioxidants, greatly influences the number and function of these circulating angiogenic cells. Read full press release to find out more at:


189329_webThis review will discuss the effects of advancing age on endothelial health and vascular regenerative capacity, as well as the influence of diet, exercise, and obesity on these cells, the mechanistic links and the subsequent impact on cardiovascular health.


This article by Dr. Mark D. Ross is published in Current Cardiology Reviews, Volume 14, Issue 4, 2018. To obtain the article, please visit:

EDITOR’S CHOICE ARTICLE – The Potential Mechanisms of Exercise-induced Cognitive Protection: A Literature Review

Journal Name: Current Pharmaceutical Design

Author(s): Jennifer E. Norman*, Jennifer Rutkowsky, Sue Bodine, John C. Rutledge.





Dementia has become a major health concern for the aging population of the United States. Studies indicate that participation in moderate exercise, with training, has been shown to have a beneficial impact on cognition. Thus, exercise and its effects on cognitive function has become an important area of research. This review summarizes the current literature on the potential mechanisms of the benefits of exercise for cognitive function.


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Yoga Every Day Keeps The Doctor Away!

Health is the first key for joyful life and in today’s world everybody aspires to have a healthy life. But the most important question exists that how to maintain or get the aspiring lifestyle, for no one gets healthier out of the blue. It needs a lot of focus especially when the influences from outside make it hard to be healthy.   Devising a healthy lifestyle is about putting structures in place that are conducive for our body and the brain. Certain routines make it easier to achieve a healthy life. Intake of balance diet and exercises like yoga helps to lead a good healthy life. Yoga makes people fit, mentally as well as physically.


New research suggests a regular practice of yoga may lower an inflammatory protein that is normally linked to aging and stress. The University of Nottingham also conducted a study and found that certain routines of yoga can also possibly help in improving the health and psychological wellbeing of children in care. Another study was conducted by the researchers from the University of Texas and it revealed that yoga helped women undergoing radiation therapy to reduce fatigue and it also improved their mental outlook. Ohio State University published a study in which it was found that yoga also helps women who had completed cancer treatment to reduce inflammation, it also helps increase energy and improves mood.

Therefore, Yoga helps to live a healthy life.  It renders us to be stronger, heals aches and pains, and keeps sickness at bay. It may also help people with depression and other mental conditions.

Build Yourself Up with Chin-Ups!

There is nothing more motivating than to build muscles in the gym. Those who have not tried it can never understand what it feels like breaking barriers on weights and machines. One of the best exercises among the lot is chin-ups. Chin-ups are a complete body workout where more than a dozen muscles are involved.


Here are certain benefits to entice you towards chin-ups.

  1. It helps build arms, chest and back muscles. When you are lifting your body there is a lot of energy exerted. This strengthens a number of big and small muscles of the body.
  2. It is a classic fighter against mental stress. Like most exercises, chin-ups also release stress relieving hormones in the mind and relaxes the body.
  3. This muscle enhancer also generates growth hormones as well as testosterones that keep us young, energized, growing and in high spirits.
  4. It is surprisingly among the top ab workouts which get the ab muscles shaped up.
  5. If you are an athlete it is vital for you to be able to manage your own bodyweight. Chin-ups are crucial in giving this much strength to the arms and supporting parts that they can carry you well.

Testimonial by Dr. Kimberley Larisa Way!


Dr. Kimberley Larisa Way

Faculty of Health Sciences, Lidcombe. Charles Perkins Centre,

Camperdown, University of Sydney NSW 2006, Australia 

Contributed Article: The Effect of Exercise on Vascular Function and Stiffness in Type 2 Diabetes: A Systematic Review and Meta-analysis

Podcast by Dr. Dioguardi ::: Nutrition, Nitrogen Requirements, Exercise and Chemotherapy-Induced Toxicity in Cancer Patients

 To watch more podcasts on articles and ebooks, please visit:

Health and fitness habits ‘influence health over next two decades’


New research from the Karlsruhe Institute of Technology in G

gests that our health and fitness habits can predict the outcome of our overall fitness and health almost 20 years later. This is according to a study published inermany sug

 the journal Psychology of Sport and Exercise.

The researchers, in collaboration with investigators from Technische Universität München, and the universities of Konstanz and Bayreuth, all in Germany, analyzed 243 women and 252 men who were an average age of 45 at study baseline.

The participants were followed-up from 1992 to 2010. They were required to complete a series of questionnaires and carried out medical and fitness tests in the years 1992, 1997, 2002 and 2010.

The researchers used a four-stage “biopsychosocial model” to pinpoint factors that could have an impact on future health and fitness.

The first stage included environmental factors, such as socioeconomic status and migration background. The second stage consisted of personal factors, including social support, stress management strategies and the feeling of coherence.

Behavioral factors, such as smoking, physical exercise and nutrition habits made up the third stage, while the fourth stage consisted of physical fitness and health.

Health and fitness habits ‘affect us 18 years later’

From their analysis, the investigators found all factors in all four stages had both a direct and indirect impact on participants’ physical fitness and health in 1992.

The areas that had the most influence included migration background, socioeconomic status, stress management strategies, expectations of exercise impact, and physical exercise and nutrition habits.

However, the researchers found that nutrition and physical exercise habits reported at the baseline of the study affected the fitness of participants during the following 18 years later, up until 2010.

The investigators say they also found that migration background and socioeconomic status indirectly influenced health habits in the 18 years after study baseline.

Commenting on the findings, Prof. Alexander Woll, of the Institute of Sports and Science at the Karlsruhe Institute of Technology, says:

“The results of our study reveal how important it is to acquire health-promoting habits at early adult age already. This should also be in the focus of prevention measures.”

The researchers note that they were surprised to find no direct relationship between physical fitness and health itself when measuring participants’ body mass index (BMI), waist-hip ratio, blood pressurecholesteroland uric acid.

They say this finding could be due to the fact that the fitness test used in the study did not take endurance into account, and this is a factor that can largely impact health.

But they point out that previous research has shown that changes to physical fitness also influence risk factors relevant to health. The research team concludes that they plan to further investigate these results to better determine how health and fitness behaviors impact future health.

Last year, Medical News Today reported on a study suggesting that even if a person does not become physically active until later in life, their health will still see benefits.

[Source: medicalnewstoday,com]

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