HIGHLIGHTED ARTICLE – SYNTHESIS OF NEW HETEOARYL SUBSTITUTED MORPHOLINE TAGGED TRIAZINES AND EVALUATION OF THEIR CYTOTOXIC ACTIVITY – LETTERS IN DRUG DESIGN & DISCOVERY

To access the article, please visit: http://www.eurekaselect.com/152922/article

Highlighted Article – Exploration of Angiotensin II Type 1 Receptor Modulators by Molecular Fingerprints and Docking Simulations – Letters in Drug Design & Discovery

To access this article, please visit: http://www.eurekaselect.com/152926

Highlighted Article – CETP Inhibitory Activity of Chlorobenzyl Benzamides – Letters in Drug Design & Discovery

http://www.eurekaselect.com/151544/article

New Issue :: Letters in Drug Design & Discovery 14, Issue 5

Letters in Drug Design & Discovery publishes letters, mini-reviews, highlights and guest edited thematic issues in all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis is on publishing quality papers very rapidly by taking full advantage of latest Internet technology for both submission and review of manuscripts. The online journal is an essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Articles from the journal Letters in Drug Design & Discovery 14, Issue 5:

• The Decisive Role of Mutual Arrangement of Hydroxy and Methoxy Groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity
• Possible Binding Mode Analysis of Pyrazolo-triazole Hybrids as Potential Anticancer Agents through Validated Molecular Docking and 3D-QSAR Modeling Approaches
• Synthesis of Novel 4-(Dimethylaminoalkyl)piperazine-1-carbodithioa t e Derivatives as Cholinesterase Inhibitors
• Synthesis, Docking and Antidiabetic Activity of Some Newer Benzamide Derivatives as Potential Glucokinase Activators
• Cytotoxic, Apoptotic and DNA Synthesis Inhibitory Effects of Some Thiazole Derivatives
• Synthesis of Phosphorylated Derivatives of 2′, 3′-O-Isopropylidene Adenosine and their In Ovo Antiviral Activity
• Synthesis of Mannich Bases by Two Different Methods and Evaluation of their Acetylcholine Esterase and Carbonic Anhydrase Inhibitory Activities
• Computational Analysis of Pyridopyrimidine-based Polo Like Kinase 2 (PLK2) Inhibitors: Examining the Structural Basis for Anticancer Activity
• In Vivo Antimalarial and In Vitro Antileishmanial Activity of 4- Aminoquinoline Derivatives Hybridized to Isoniazid or Sulfa or Hydrazine Groups
• Vitamin B12 Controlled Release with Crosslinked Poly (Acrylic Acid) and Poly (Methacrylic Acid) Based on Chitosan and Starch as pH Sensitive Hydrogels
• Quorum Sensing Inhibitor Activities of Celecoxib Derivatives in Pseudomonas aeruginosa
• NF-κB Inhibitors in Head and Neck Cancer

For details on the articles, please visit this link :: http://bit.ly/2t8wJsF

 

 

 

 

Highlighted Article – A Study on Identification of Nutraceutical Value of New Imidazolone Schiff Base Analogues – Letters in Drug Design & Discovery

http://www.eurekaselect.com/151536/article

New Issue :: Letters in Drug Design & Discovery 14, Issue 4

Letters in Drug Design & Discovery publishes letters, mini-reviews, highlights and guest edited thematic issues in all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis is on publishing quality papers very rapidly by taking full advantage of latest Internet technology for both submission and review of manuscripts. The online journal is an essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Articles from the journal Letters in Drug Design & Discovery 14, Issue 4:

• Quinoline Derivatives as Novel Depigmenting and Antioxidant Agents
• Synthesis and Antioxidant Activity of Indole Derivatives Containing 4-Substituted Piperazine Moieties
• In Silico Modeling for the Design of 2-substitted Benzimidazole Derivatives, and Prediction of Activity as Procaspase-3 Activators and Apoptosis Inducer
• Synthesis, Antiproliferative, and Antiangiogenic Activities of Benzochromene and Benzoquinoline Derivatives on Prostate Cancer in vitro
• 3D-QSAR and Molecular Docking Studies of Pyrazole Derivatives as Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis
• Synthesis, Molecular Docking and Pharmacological Study of Pyrimidothiadiazinones and its bis-derivatives
• Structure-Based Hybridization, Conventional and Microwave Irradiated Synthesis, Biological Evaluation and Molecular Docking Studies of New Compounds Derived from Thiomorpholin
• Improved Anti-inflammatory Activity and Potential Cytoprotective Properties of Tolfenamic Acid, Naproxen and Indomethacin Derivatives
• Chronobiotic Hormone Melatonin: Comparative in vitro Release Studies from Matrix Tablets and Liposomal Formulations
• Caffeic Acid Phenethyl Ester Restores Adipocyte Gene Profile Expression Following Lipopolysaccharide Treatment
• Pharmacokinetic Evaluation of Callistemon viminalis Derived Natural Compounds as Targeted Inhibitors Against δ -Opioid Receptor and Farnesyl Transferase
• Sequential Therapy For Helicobacter pylori in Elderly Patients: Effectiveness, Safety and Predictors of Success
  

For details on the articles, please visit this link :: http://bit.ly/2rOKR7H