Dr. Alberto Marra serves as the Editor-in-Chief of the Journal “Letters in Organic Chemistry”
Alberto Marra
University of Montpellier
Montpellier
(France)
Biography
Tag: Letters in Organic Chemistry
Aims & Scope | Letters in Organic Chemistry
Letters in Organic Chemistry publishes original letters (short articles), research articles, full-length/mini-reviews and thematic issues based on mini-reviews and short articles, in all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is to publish quality papers rapidly by taking full advantage of latest technology for both submission and review of the manuscripts.
The journal is an essential reading for all organic chemists belonging to both academia and industry. To learn more about the journal, please visit: https://benthamscience.com/journals/letters-in-organic-chemistry/
Most Accessed Articles | Synthesis and Biological Evaluation of PF-543 Derivative
Journal Name: Letters in Organic Chemistry
Author(s): Seon Woong Kim, Taeho Lee, Joo-Youn Lee, Sanghee Kim, Hee-Sook Jun, Eun-Young Park*, Dong Jae Baek*.
PF-543 has been known as a substance that strongly inhibits SK1. However, it also exhibits antineoplastic activity that is lower than other inhibitors of SK1. In this study, we compared PF-543 and synthesized a newly designed derivative of PF-543 (compound 2) in which two aromatic structures were connected in para-form. The synthesized derivative showed inhibitory effect on SK1, similar to that of PF-543. However, it was more cytotoxic to HT29, AGS, and PC3 cells than PF-543. We also carried out a docking study for SK1 and demonstrated that the synthesized derivative showed interaction with SK1 similar to PF-543. Results obtained from this study suggest that the structure of compound 2 may be well substituted for the structure of PF-543 in terms of biological activity, providing us important structural information for the design of new derivatives of PF-543. Read out full article here: http://www.eurekaselect.com/166082
Open Access Articles | Synthesis of 1-(3-Phenylpropyl)-4-(pyridinylmethoxy)-[1,2,4]triazolo[4,3-a] quinoxalines
Journal Name: Letters in Organic Chemistry
Author(s): Dominik Summer, Barbara Matuszczak*
Starting from 2,3-dichloroquinoxaline, a synthetic strategy for the preparation of 1-(3- phenylpropyl)-4-(pyridinylmethoxy)[1,2,4]triazolo[4,3-a]quinoxalines is described. Read out full article here: http://www.eurekaselect.com/163737
New Issue | Letters in Organic Chemistry
Letters in Organic Chemistry publishes original letters (short articles), research articles, full-length/mini-reviews and thematic issues based on mini-reviews and short articles, in all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is to publish quality papers rapidly by taking full advantage of latest technology for both submission and review of the manuscripts.
The journal is an essential reading for all organic chemists belonging to both academia and industry.
Articles from the journal Letters in Organic Chemistry Volume: 16, Issue: 6
- Synthesis of Novel Hybrid Scaffolds of Pyran Chalcone Derivatives Bearing Indole and Pyrrole Rings
- Synthesis and Antitumor Activity Evaluation of New Phenanthrene-Based Tylophorine Derivatives
- Microwave-assisted One-pot Synthesis of 7-Dimethylamino-4-Aryl-2- methylamino-3-nitro-4H-chromenes
- Isolation of New Glycosides from Anemarrhena Asphodeloides Rhizome and Screening of their Anticancer Activity
- Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents
- Transition Metal-free Trifluoroethoxylation of Diaryliodonium Salts and Fluoro Alcohols
- Nano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols
- Microwave-Assisted Synthesis of Chiral Oxime Ethers
- Synthesis, Antioxidant Activity and Theoretical Investigation of Isoxazolines Derivatives of Monoterpenoids
- Synthesis of Novel Bis-pyrazoles via Electrophilic Cyclization
- Synthesis and Anti Lung Cancer Activity of 3-Arylspiro[oxirane-2,3′- thiochroman]-4′-one Derivatives
For details on the articles, please visit this link: http://www.eurekaselect.com/node/625/letters-in-organic-chemistry/issue/16/2525/6/9026
New Issues of various Bentham Science Journals
1. Cardiovascular & Hematological Agents in Medicinal Chemistry, Vol: 16, Issue:1
https://bit.ly/2AWUnwp
2. Letters in Organic Chemistry, Vol: 15, Issue: 10
https://bit.ly/2QCmhCY
3. Current Vascular Pharmacology, Vol: 16, Issue: 6
https://bit.ly/2AVbmiI
4. Current Pharmaceutical Design, Vol: 24, Issue: 17
https://bit.ly/2PSKAzs
5. Recent Patents on Inflammation & Allergy Drug Discovery, Vol: 12, Issue: 2
https://bit.ly/2QrcEqY
6. Current Organic Chemistry, Vol: 22, Issue: 15
https://bit.ly/2SXAnAH
7. Current Pharmaceutical Design, Vol: 24, Issue: 18
https://bit.ly/2PK2qF3
8. Recent Patents on Biotechnology, Vol: 12, Issue: 3
https://bit.ly/2z29KlC
9. Mini-Reviews in Medicinal Chemistry, Vol: 18, Issue: 16
https://bit.ly/2qCXROI
New Issue :: Letters in Organic Chemistry 15, Issue 7
Letters in Organic Chemistry publishes original letters, mini-reviews and guest edited issue in all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is to publish quality papers rapidly by taking full advantage of latest technology for both submission and review of the manuscripts.
The journal is an essential reading for all organic chemists belonging to both academia and industry.
Articles from the journal Letters in Organic Chemistry Volume 15, Issue 7:
- QSAR Analysis of 6-Fluoro-3-(4H- 1,2,4-triazol-3-yl)quinolin-4(1H)-ones as Antileukemic Agents using Physicochemical and Alignment Independent Topological Based Descriptors
- Ru (III) Schiff base Complex Anchored onto Rice Husk Derived Nanosilica Support: An Efficient Heterogeneous Catalyst for Oxidation of Alcohols
- A Novel Approach for Substitution of Sulfonate Group by (1H)-imidazole moiety: An Application for Synthesis of Novel Benzyl Imidazolylcarbamates
- Synthesis, Characterization and Antibacterial Activity of Some New 1,2,4- Triazole Schiff bases and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines
- DABCO-bis-CC: An Efficient Alternative to PCC
- Recyclable Magnetic Copper Ferrite Nanoparticle Catalyzed One-pot Four-component Dakin-West Reaction: Efficient Synthesis of β-Acetamido Ketones
- An Efficient Gram Scale Synthesis of Aryl Iodides from Aryl Diazofluoroborates in Water under Mild Conditions
- A One-Pot Multicomponent Synthesis of Naphthoxazin-3-one Derivatives Using Amberlite IRA-400 Cl Resin as Green Catalyst
- Schmidt Reaction on Substituted 1-Indanones / N-Alkylation: Synthesis of Benzofused Six-membered Ring Lactams and their Evaluation as Antimicrobial Agents
- Generation of β-Linked GlcNac and GalNAc Terminating Disaccharide Library through Glycosylation on Unprotected Monosaccharides
- Rapid and Efficient Synthesis, Characterization and Antimicrobial Activity of Some Methylanthranilate Derived Odorant Schiff Bases
- Metal-Free HNO3/TEMPO-Catalyzed Conversion of Benzyl Alcohols to Aromatic Nitriles with Oxygen Molecule as the Terminal Oxidant
- A Green Ultrasound Synthesis, Characterization and their Antibacterial Evaluation of Novel Transition Metal Complex of 2-amino-5-Aryl-1, 3, 4- THIADIAZOLE
For details on the articles, please visit this link :: https://bit.ly/2l8o7O7
EDITOR’S CHOICE – An Efficient Gram Scale Synthesis of Aryl Iodides from Aryl Diazofluoroborates in Water under Mild Conditions
Journal: Letters in Organic Chemistry
Graphical Abstract:
Abstract:
Transition metal-free synthesis of synthetically valuable aryl iodides from aryl diazofluroborates in water under mild conditions has been described. Majority of synthesized aryl iodides are obtained in quantitative yields (>99 %) under present reaction conditions. The structural effects due to the substituents present on aryl diazofluoroborates did not show any satisfactory effect on the yields of the aryl iodides. Hence, the methodology presented here was found to be adventitious for the quantitative production of synthetically valuable aryl iodides.
Read more here: http://www.eurekaselect.com/155407/article
RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS
Recent Patents on Engineering 12-1
Current Molecular Medicine 17-7
Letters in Organic Chemistry 15-4
Letters in Drug Design & Discovery 15-4
Current Pharmaceutical Biotechnology 18-12
EDITOR’S CHOICE – Divergent Synthesis of Novel Dienylbenzothiazoles and Arylidenedibenzoxazepines and Evaluation of Their Antiproliferative and Cytotoxic Properties – LETTERS IN ORGANIC CHEMISTRY
Journal: Letters in Organic Chemistry
Author(s): P.R. Kathiravan*, S. Muthukumaran, N. Dhatchanamoorthy, T. Shanmuganathan, M. Venugopal
Graphical Abstract:
Abstract:
Background: Dibenzo-oxazepine and Benzothiazole derivatives are used as antipsychotics, anticancer, antibacterial and anti-inflammatory agents.
Methods: Arylidene derivatives of 1,2,3,4-Tetrahydro-Dibenzo[b,f][1,4]Oxazepine and 2-[2-Chloro- Cyclohex-1-enyl]- Benzothiazoles were synthesized by reacting benzylidene derivative of chloroaldehyde with 2-aminophenol and 2-aminothiophenol respectively. Benzylidene derivative of chloroaldehyde was prepared by Vilsmeier reaction of 2-benzylidenecyclohexanone derivatives, which were obtained from the condensation of various aromatic aldehydes with cyclohexanone.
Results: Benzylidene derivatives of 1,2,3,4-Tetrahydro-Dibenzo[b,f][1,4]Oxazepine 6a-g exhibited promising antiproliferative activity with GI50 values in the micromolar range. The compounds containing halo, alkyl and alkoxyl groups as substituents on the benzylidine ring have been found to be very effective cytotoxic agents.
Conclusion: This study identified dibenzo-oxapine as a prospective pharmacophore which set the stage for thorough exploration of this compound class as cytotoxic agents.
Read more here: http://www.eurekaselect.com/153003/article
Bentham Science 
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