Bentham Science observes World Glaucoma Week from 8th to 15th March, 2018, with the world and presents full support for the victims of glaucoma through publishing the latest research developments to combat this dangerous eye disease. Glaucoma is a widely feared eye problem because it causes irreversible blindness. Eye researchers and ophthalmologists have mostly attributed glaucoma to the increase in intraocular pressure, i.e. the increase in fluid pressure inside the eye.
However there are cases where the glaucoma patients had normal intraocular pressure, which suggests that there are other factors that can cause or enhance the risk of contracting this disease. Researchers from the Ophthalmology Unit of the University of Rome Tor Vergata have recently discovered that the patients of Alzheimer’s were often found susceptible of getting glaucoma in their eyes. Alzheimer’s disease is the most common form of dementia in the elderly that hampers memory and understanding.
Both these neurodegenerative diseases were found to have very similar risk factors and often co-existed in the older people. The research is an important revelation and opens doors for future studies and possible progress in finding cure for both Alzheimer’s disease and glaucoma.
The research entitled, Glaucoma and Alzheimer Disease: One Age-Related Neurodegenerative Disease of the Brain, is published in the Bentham Science journal, Current Neuropharmacology.
Journal: Current Medical Imaging Reviews
Author(s): Tomasz K. Nowicki*, Karolina Markiet, Edyta Szurowska
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, which develops mostly in the setting of chronic liver disease. European Association for the Study of the Liver (EASL) and European Organization for Research and Treatment of Cancer (EORTC) prepared guidelines for screening, follow-up and diagnosis of HCC to facilitate decision making and optimize both diagnostic and therapeutic protocols.
The review briefly describes etiology, epidemiology and histopathology of HCC and presents EASL-EORTC guidelines for surveillance and diagnosis of HCC. Target population and screening algorithm is presented in the surveillance section. Ultrasound imaging of HCC and the role of contrast enhanced ultrasound are described as well as the value of laboratory tests in screening. Further, radiological features of HCC in multiphase CT and dynamic contrast enhanced MRI and diagnostic criteria are presented. Additionally, the advantages of advanced techniques in MRI such as diffusion weighed imaging and the use of hepatocyte-specific contrast agents are discussed.
Lastly, the EASL-EORTC guidelines are compared with the guidelines of the American Association for the Study of Liver Diseases and the Japan Society of Hepatology. Also LI-RADS and the Barcelona Clinic Liver Cancer classification are mentioned.
In the near future, due to the ongoing advances in imaging a revision of the guidelines may be expected.