Become a Reviewer | Journal of Photocatalysis

 

Journal of Photocatalysis” would publish high quality research papers, reviews, and short communications focused on photocatalysis from many different scientific areas including Chemistry, Chemical Engineering, Materials Science, Materials Engineering, Environmental Engineering, Nanotechnology and Green Chemistry.

Journal of Photocatalysis” would accept novel papers in the following fields:

  • Preparation and characterization of new photocatalysts.
  • Photocatalytic elimination of environmental pollutants in liquid or gas phase.
  • Self-cleaning materials.
  • Thin films.
  • Photocatalytic syntheses of valuable products.
  • Photocatalytic hydrogen generation and CO2 reduction.
  • Kinetics and mechanistic aspects of photocatalytic reactions.
  • Combination of photocatalysis with other technologies, such as membrane technologies and photoelectrocatalysis.
  • Engineering aspects of photocatalytic processes.
  • Homogeneous photocatalysis.
  • Theory, modelling and computational aspects regarding the mechanisms of activation of photocatalysis.

The Journal Journal of Photocatalysis is interested in appointing active Reviewer on the Journal’s Board. If you are working in the related field as of the journal and are interested in becoming an Reviewer, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field, you can recommend suitable colleagues for the same, and, if possible, send their CV along with their list of publications. Mention in the subject line, the field of interest and send your CV at: hermain@benthamscience.net and CC: faizan@benthamscience.net

 

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Become an Editorial Board Member (EBM) | Journal of Photocatalysis

 

Journal of Photocatalysis” would publish high quality research papers, reviews, and short communications focused on photocatalysis from many different scientific areas including Chemistry, Chemical Engineering, Materials Science, Materials Engineering, Environmental Engineering, Nanotechnology and Green Chemistry.

Journal of Photocatalysis” would accept novel papers in the following fields:

  • Preparation and characterization of new photocatalysts.
  • Photocatalytic elimination of environmental pollutants in liquid or gas phase.
  • Self-cleaning materials.
  • Thin films.
  • Photocatalytic syntheses of valuable products.
  • Photocatalytic hydrogen generation and CO2 reduction.
  • Kinetics and mechanistic aspects of photocatalytic reactions.
  • Combination of photocatalysis with other technologies, such as membrane technologies and photoelectrocatalysis.
  • Engineering aspects of photocatalytic processes.
  • Homogeneous photocatalysis.
  • Theory, modelling and computational aspects regarding the mechanisms of activation of photocatalysis.

 

The Journal Journal of Photocatalysis is interested in appointing active Editorial Board Member  on the Journal’s Board. If you are working in the related field as of the journal and are interested in becoming an Editorial Board Member, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field, you can recommend suitable colleagues for the same, and, if possible, send their CV along with their list of publications. Mention in the subject line, the field of interest and send your CV at: hermain@benthamscience.net and CC: faizan@benthamscience.net

 

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OPEN ACCESS ARTICLE – The Role of Phosphorus Trichloride and Phosphorous Acid in the Formation of α-Hydroxymethylenebisphosphonic Acids from the Corresponding Carboxylic Acids – A Mechanistic Overview

Journal Name: Current Organic Chemistry

Author(s): Dávid Illés Nagy, Alajos Grün, István Greiner, Gyorgy Keglevich*.

 

 

Graphical Abstract:

 

 

Abstract:

Background: Although the synthesis of α-hydroxymethylenebisphosphonic acids (dronic acids) and derivatives by reaction of the corresponding carboxylic acids (or its derivatives) with P-reagents, such as phosphorus trichloride, phosphorous acid and phosphoryl chloride formed the subject of many studies, in most cases, the selection of the P-reagents, their ratio, and the conditions (solvent and temperature) were not optimized.

Method: Selection of the appropriate P-reagents and their ratios, along with the conditions is possible, only if the reaction protocol (sequence of the steps) or the mechanism is known. For this purpose, the relevant information was extracted from the literature, critically discussed and the conclusions were drawn. Our own experiences are also summarized on the possible mechanisms, and on the related optimum set of the reaction parameters depending mainly on the nature of the solvent used.

Conclusion: This review gives a better understanding of the dronate chemistry, and promotes “greener” and more practical syntheses.

 

Read more here: http://www.eurekaselect.com/151654

EDITOR’S CHOICE – Current Delivery Strategies to Improve the Target of Cell Penetrating Peptides Used for Tumor-Related Therapeutics

Journal: Current Pharmaceutical Design

Author(s): Fang Zhang, Dandan Yang, Shanshan Jiang, Lei Wu, Li Qin, Huiyang He, Peng Zhang*

Abstract:

Cell Penetrating Peptides (CPPs) equipped with a high penetrating ability are used as a promising tool to gain access to the cell interior, cross the cell membrane and deliver bioactive small or macromolecular cargos into the cytoplasm or nucleus. The superiority of wide range of applications, high transport efficiency and low biological toxicity make them particularly desirable in laboratory or clinical studies. Previous studies have shown that their non-selectivity and reaction with proteins in plasma hamper their application for tumor therapy, which might adversely affect the treatment effect and even induce some side effects. However, several recent studies have found that various kinds of modifiers of CPPs can effectively increase the target selectivity, reduce cytotoxicity to normal cells and produce multiple antitumor functions due to the different cleavable bonds which are sensitive to the tumor microenvironment or other novel designs. Apparently, these designs of ‘smart’ CPPs appear to be promising in the field of antitumor drug delivery. Here, we review these current improved approaches which mainly involve strategies of physical, chemical as well as biological pathways and we also explain the possible uptake mechanisms of direct penetration, internalization and escape which have been discussed in some publications with specific attention. In addition, some possible problems needed to be considered in the process of improving CPPs are discussed at the end of this review. This study aims to present an overview of the latest progress of CPPs, and provides a comprehensive theoretical background and reference guidance for future laboratory research and clinical application.

Read more here: http://www.eurekaselect.com/154537/article

 

 

OPEN ACCESS ARTICLE – The Role of Phosphorus Trichloride and Phosphorous Acid in the Formation of α-Hydroxymethylenebisphosphonic Acids from the Corresponding Carboxylic Acids – Current Organic Chemistry

Journal: Current Organic Chemistry

Author(s): Dávid Illés Nagy, Alajos Grün, István Greiner, Gyorgy Keglevich

Graphical Abstract:

 

Abstract:

Background: Although the synthesis of α-hydroxymethylenebisphosphonic acids (dronic acids) and derivatives by reaction of the corresponding carboxylic acids (or its derivatives) with P-reagents, such as phosphorus trichloride, phosphorous acid and phosphoryl chloride formed the subject of many studies, in most cases, the selection of the P-reagents, their ratio, and the conditions (solvent and temperature) were not optimized.

Method: Selection of the appropriate P-reagents and their ratios, along with the conditions is possible, only if the reaction protocol (sequence of the steps) or the mechanism is known. For this purpose, the relevant information was extracted from the literature, critically discussed and the conclusions were drawn. Our own experiences are also summarized on the possible mechanisms, and on the related optimum set of the reaction parameters depending mainly on the nature of the solvent used.

Conclusion: This review gives a better understanding of the dronate chemistry, and promotes “greener” and more practical syntheses.

 

HIGHLIGHTED ARTICLE – MYCOSPORINE- LIKE AMINO ACIDS FOR SKIN PHOTOPROTECTION – CURRENT MEDICINAL CHEMISTRY

Cmc-Articles_24-42-Karl P Lawrence

To access the article, please visit: http://www.eurekaselect.com/152756/article

Most Accessed Article – “Drug Interactions with Angiotensin Receptor Blockers: Role of Human Cytochromes P450”

Journal: Current Drug Metabolism

Author(s): Ruirui Yang, Zhiqiang Luo, Yang Liu, Mohan Sun, Ling Zheng, Yingying Chen, Yanping Li, Hao Wang, Lingzhu Chen, Ming Wu and Huihui Zhao

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Abstract:

Background: Angiotensin receptor blockers (ARBs) are the most recent class of agents for the treatment of hypertension. However, ARBs may cause a low incidence of headache, upper respiratory infection, back pain, muscle cramps, fatigue, dizziness, and many other side effects. In some cases, such toxicity is associated with pharmacokinetic alterations.

Methods: The cytochrome P450 (CYP) enzyme system plays an important role in a lot of clinically important pharmacokinetic drug interactions. To identify relevant studies on drug-drug and food-drug pharmacokinetic interactions with the ARBs, a literature search of Google Scholar was performed from January 1994 to June 2015, with the following keywords: ‘losartan’, ‘valsartan,’ ‘candesartan,’ ‘irbesartan,’ ‘telmisartan,’ ‘eprosartan,’ ‘olmesartan,’ and ‘azilsartan’, combined with the keyword ‘pharmacokinetic interactions’ and ‘CYP’.

Results: Based on the literatures published, it has been demonstrated that pharmacokinetic interactions of losartan with other agents are mainly via CYP2C9- and CYP3A4-mediated, the role played by CYP enzyme system in the metabolism of valsartan, candesartan, irbesartan, and azilsartan appears modest, and cytochrome P450 system has no influence on the metabolism of telmisartan, eprosartan, olmesartan. Therefore, according to these pharmacokinetic findings, no dosage adjustment is recommended when eprosartan, telmisartan and olmesartan are combined with other pharmacological agents in patients with hypertension.

Conclusion: This review summarize the available data on cytochrome P450 – related drug–drug interactions reported in the literature for the eight ARBs. Knowledge of the pharmacokinetic properties of the ARBs should allow the avoidance of the majority of drug interactions without compromising therapeutic benefits.

To access the article, please visit: http://benthamscience.com/journals/current-drug-metabolism/volume/17/issue/7/page/681/

Plants Can Learn!

Study shows plants can learn!
Plants may lack brains and neural tissues but they do possess a sophisticated calcium-based signally network in their cells similar to animals’ memory processes, they write.
The researchers concede that they do not yet understand the biological basis for this learning mechanism, nevertheless their set of experiments has major implications – not least, it radically changes the way we perceive plants and the boundaries between plants and animals, including our definition of learning (and hence memory) as a property special to organisms with a nervous system function of a nervous system.

[Source: sciencealert.com]Image

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