RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Bioactive Compounds 14-2

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Current Topics in Medicinal Chemistry 18-5

https://bit.ly/2JvIWSg

Mini-Reviews in Medicinal Chemistry 18-11

https://bit.ly/2l7XtoF

Current Hypertension Reviews 14-1

https://bit.ly/2MgTgv0

Recent Innovations in Chemical Engineering 11-1

https://bit.ly/2HHqAI5

Current Cancer Drug Targets 18-6

https://bit.ly/2JO5e0P

RIA

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Molecular Medicine 17, Issue 8
https://bit.ly/2vxb2Ws

Current Medicinal Chemistry 25, Issue 7
https://bit.ly/2Hgx8y2

Anti-Cancer Agents in Medicinal Chemistry 18, Issue 1
https://bit.ly/2HggSBd

Mini-Reviews in Medicinal Chemistry 18, Issue 6
https://bit.ly/2qLnhKe

Current Medicinal Chemistry 25, Issue 8
https://bit.ly/2HfMwyK

Current Drug Targets 19, Issue 5
https://bit.ly/2qNNjfZ 

RIA

 

WISHING A VERY HAPPY BIRTHDAY TO DR. GEORGE PERRY!

Dr. George Perry.jpg

DR. GEORGE PERRY

EDITOR-IN-CHIEF: MINI-REVIEWS IN MEDICINAL CHEMISTRY & Letters in Drug Design & Discovery

COLLEGE OF SCIENCES,
THE UNIVERSITY OF TEXAS AT SAN ANTONIO,
TEXAS,
USA

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Protein & Peptide Science Volume 19, Issue 4
http://bit.ly/2oANZTZ

Combinatorial Chemistry & High Throughput Screening Volume 20, Issue 10
http://bit.ly/2CKt8CO

Current Pharmaceutical Biotechnology Volume 18, Issue 11
http://bit.ly/2F8GJZG

Endocrine, Metabolic & Immune Disorders – Drug Targets Volume 18, Issue 2
http://bit.ly/2HPH2Y6

Mini-Reviews in Medicinal Chemistry Volume 18, Issue 5
http://bit.ly/2BSPLIw

Current Drug Delivery Volume 15, Issue 2
http://bit.ly/2ozzaB9

recent-issues

MOST ACCESSED ARTICLE – Lysine-derived Alkaloids – Mini-Reviews in Medicinal Chemistry

Journal: Mini-Reviews in Medicinal Chemistry

Author(s): Somnuk Bunsupa*, Mami Yamazaki*, Kazuki Saito

Graphical Abstract:

Abstract:

Background: Plants produce a vast variety of specialized metabolites which can be a rich source for lead compounds for the development of new drugs. Alkaloids are one the largest groups of plant specialized metabolites important for natural product based pharmaceuticals. Of these, lysine (Lys)-derived alkaloids exhibit a wide range of pharmacological properties which are beneficial for humans. For instance they have anticancer, anti-Alzheimer’s disease, anti-inflammatory, hypocholesterolemic and antiarrhtymic effects. Lys-derived alkaloids are widely distributed throughout the plant kingdom: they can be found in various species from clubmosses to flowering plants. Lys is one of the most essential amino acids for humans and livestock and is synthesized in the plastids of land plants. Lys-derived alkaloids can be divided into four major groups including quinolizidine, lycopodium, piperidine, and indolizidine alkaloids. Despite the importance of these compounds, the biosynthetic pathways of Lys-derived alkaloids are not well understood. With the exception of indolizidine alkaloids, Lys decarboxylase (LDC) is the enzyme involved in the first committed step of the biosynthesis by catalyzing the transformation of L-Lys into cadaverine. Cadaverine is then oxidized by copper amine oxidase (CuAO) and spontaneously cyclized to Δ1-piperideine Schiff base which is a universal intermediate for the production of various Lys-derived alkaloids.

Conclusion: In this review, we briefly summarize the recent understanding about the structures, occurrences, analytical procedures, biosyntheses, and potential health effects and medical applications of Lys-derived alkaloids with emphasis on quinolizidine alkaloids (QAs).

To access the article, please visit: http://www.eurekaselect.com/141902

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Protein & Peptide Letters 24-11

http://bit.ly/2DeaIfs

Mini-Reviews in Medicinal Chemistry 18-2

http://bit.ly/2qRzOOI

Mini-Reviews in Medicinal Chemistry 18-3

http://bit.ly/2CMj5Ov

Innovations in Corrosion and Materials Science 7-2

http://bit.ly/2mmdwQp

Current Pharmaceutical Design 23-33

http://bit.ly/2qPs6oo

recent-issues

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Current Physical Chemistry 7 – 4

http://bit.ly/2BGhH2z

MicroRNA 6 – 3

http://bit.ly/2APY58r

Current Molecular Medicine 17 – 4

http://bit.ly/2kdMd9Z

Mini-Reviews in Medicinal Chemistry 18 – 1

http://bit.ly/2CXqTxp

Current Cancer Drug Targets 18 – 1

http://bit.ly/2jdhhpF

Letters in Organic Chemistry  15 – 1

http://bit.ly/2oAE3Nz

Current Pharmaceutical Analysis 14 – 1

http://bit.ly/2CUJl9R

Current Green Chemistry 4 – 2

http://bit.ly/2BCKZyT

Endocrine, Metabolic & Immune Disorders – Drug Targets 18 – 1

http://bit.ly/2BsTxGf

Cardiovascular & Hematological Disorders-Drug Targets 17-2

http://bit.ly/2ySrih3

recent-issues

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Drug Delivery Letters 7-3

http://bit.ly/2CSTUu5

Mini-Reviews in Medicinal Chemistry 17-17

http://bit.ly/2BrqB17

Mini-Reviews in Medicinal Chemistry 17-18

http://bit.ly/2Cxnwfq

Medicinal Chemistry 13-8

http://bit.ly/2j8h1  rM

Reviews on Recent Clinical Trials 12-3

http://bit.ly/2AU9nZy

Reviews on Recent Clinical Trials 12-4

http://bit.ly/2ARFAAF

Cardiovascular & Hematological Agents in Medicinal Chemistry 15-1

http://bit.ly/2jbxwDi

Current Analytical Chemistry 13-6

http://bit.ly/2kcWeUK

Recent Advances in Electrical & Electronic Engineering 10-3

http://bit.ly/2BFeYGu

Current Radiopharmaceuticals 10-3

http://bit.ly/2ySh28A

recent-issues

HIGHLIGHTED ARTICLE – TRYPANOTHIONE REDUCTASE: A TARGET FOR THE DEVELOPMENT OF ANTI-TRYPANOSOMA CRUZI DRUGS – MINI-REVIEWS IN MEDICINAL CHEMISTRY

MRMC-Articles-17 -18-2017-Gildardo Rivera

To access the article, please visit: http://www.eurekaselect.com/150897

Highlighted Article – Nutlin-3, A P53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment – Mini-Reviews in Medicinal Chemistry

MRMC- Articles_17-18-Voon Yee-Lin

To access this article, please visit: http://www.eurekaselect.com/154246