Most Cited Article – Feasibility and Acceptability of Instructions of Daily Care in Overweight and Obese Knee Osteoarthritis Participants

Author(s):Muhammad T. Rafiq*Mohamad S.A. HamidEliza HafizFarid A. Chaudhary and Muhammad I. Khan

Volume 17, Issue 4, 2021

Published on: 26 July, 2021

Page: [421 – 427]

Pages: 7

DOI: 10.2174/1573397117666210727095552


Introduction: Knee Osteoarthritis (OA) is a weight-bearing joint disease and is more common in overweight and obese persons. The objective of the study was to assess the feasibility and acceptability of Instructions of Daily Care (IDC) on pain, mobility, and Body Mass Index (BMI) among knee OA participants who are overweight or obese.

Materials and Methods: The study was an open-label randomized controlled trial of six weeks. Forty overweight and obese participants with knee OA were randomly divided into two groups by a computer-generated number. The participants in the Instruction Group (IG) were provided with leaflets explaining IDC for the duration of six weeks. Both groups were instructed to take low doses of the non-steroid anti-inflammatory drug (NSAIDs) on alternate days. The outcome measures were pain, mobility and BMI. The feasibility and acceptability of knee pain and mobility were assessed using a questionnaire designed by experts in rehabilitation.

Results: Participants in the IG reported more statistically significant pain relief as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index score (p=0.001) and improvement in mobility (p=0.000) assessed by the Timed Up and Go test score after six weeks compared to the Control Group (CG). Both groups did not demonstrate any significant change in BMI (p-value > 0.05). The results of descriptive statistics showed a significantly higher satisfaction score for participants who received a combination of IDC and NSAIDs, indicating an acceptable intervention.

Conclusion: The IDC is effective and acceptable in terms of improving pain and mobility and should be recommended as the usual care of treatment. Read now:

Press Release | Phytochemistry, traditional uses and pharmacological profile of rose hip


The genus Rosa from family Rosaceae is one of the most widespread species from the family. One species, rose hip (rose haw), is known as a good source of different types of micronutrients and phytochemicals such as phenolic acids, tannins, and flavonoids. It is known as a traditional treatment in folk medicine. It has been used for the treatment of several illness including ear, nose, and throat problems since old times.

This article by Dr. Amirhossein Sahebkar et al. is published in Current Pharmaceutical Design, 2018. To obtain the article, please visit:


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Read full press release to find out more at:

Women Often Suffer With Osteoarthritis – What They Can Do?!

Osteoarthritis is among the most common problems faced by women. Men also contract this problem but are fewer in count compared to women. Osteoarthritis, or arthritis, renders the bones and joints to hurt causing serious hampering in movements. These aches in joints are due to the cartilages covering the bones. With age and other hereditary reasons also, the cartilages coating the bones start to stiffen and thus break. This results in friction and, at worse, erosion of bones.


Here are a few tips for women who are bearing this painful problem:

  1. Being overweight aggravates osteoarthritis so it is essential to lose weight.
  2. Dietary habits affect a great deal. Women must take a good amount of Calcium supplements, Vitamin C and Vitamin D. Sunlight is required to keep the Vitamin D level on the higher side.
  3. Exercises are the best solution to osteoarthritis. Women need to keep active and quit lethargy. There are particular routines that provide immense assistance in keeping the joints and bones strong.
  4. Similarly, muscles must be kept strong with regular exercise. Muscles are connected to joints and if they get weak the pain increases faster. Stronger muscles keep the joints well in motion.
  5. Inflammations and pain are part and parcel for osteoarthritis. It is advisable for women to keep hot and cold packs with them. Treating joints to hot packs help relieve the pain while cold packs take care of inflammations. But both should not be used together!

The best tip for the sufferers is to enjoy life. Fun is the only cure for such persistent problems like osteoarthritis.

To women around the world: Enjoy life and a very blessed International Women’s Day 2016!!

For all your issues related to health check out our journal: Current Women’s Health Reviews

BSP Patent Journal- Recent Patents on Biomarkers

Recent Patents on Biomarkers

7-24-2014 11-31-47 AM

ISSN: 2210-3104 (Online)
ISSN: 2210-3090 (Print)

Volume 4, 3 Issues, 2014

Aims & Scope

Recent Patents on Biomarkers publishes review and research articles, and guest edited thematic issues on important recent patents on biomarkers. The coverage includes novel biomarkers in basic, medical, environmental, and pharmaceutical research. A selection of important and recent patents on biomarkers is also included in the journal. The journal is essential reading for all researchers involved in biomarker research and discovery. The journal also covers recent research (where patents have been registered) in fast emerging patent biomarker applications; discovery and validation are covered for drug discovery, clinical development and molecular diagnostics.

Abstracted & Indexed in:

Chemical Abstracts, MediaFinder®-Standard Periodical Directory, J-Gate, PubsHub, CABI.

For more details, visit:

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