EDITOR’S CHOICE – The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab

Journal: Recent Patents on Biotechnology

Author(s): Tasha R. Serna-Gallegos, Christopher J. La-Fargue, Krishnansu S. Tewari

Graphical Abstract:

 

Abstract:

Objective: Fully humanized monoclonal antibodies have revolutionized the treatment of many solid tumors, including ovarian, lung, colorectal, and breast cancer. Among the most widely used monoclonal antibodies in clinical oncology are cetuximab, trastuzumab, rituximab, and bevacizumab.

Methods: This is a review article focusing on the drug patents for cetuximab, trastuzumab, rituximab, and bevacizumab.

Results: These four monoclonal antibodies are used in both first and second line treatment regimens for multiple common malignancies. With recent patent expirations, pharmaceutical companies involved in biosimilar manufacture are looking to establish ownership over these financial monopolies.

Conclusion: This article will review these four notable monoclonal antibodies, their role in clinical oncology, and the drug patents that are nearing expiration. There are currently only two biosimilars approved in the United States: the trastuzumab biosimilar trastuzumab-dkst (Ogivri) and the bevacizumab biosimilar bevacizumab-awwb (Mvasi). In Europe, SB3, a trastuzumab biosimilar, is approved for use as well as two rituzimab biosimilars, truxima and rixathon.

Read more here: http://www.eurekaselect.com/157643/article

 

WISHING A VERY HAPPY BIRTHDAY TO DR. NIKOLAOS LABROU!

Dr. Nikolas Lab.jpg

DR. NIKOLAOS LABROU

EDITOR-IN-CHIEF: RECENT PATENTS ON BIOTECHNOLOGY

LABORATORY OF ENZYME TECHNOLOGY, DEPARTMENT OF BIOTECHNOLOGY
AGRICULTURAL UNIVERSITY OF ATHENS,
ATHENS,
GREECE

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Recent Patents on Drug Delivery & Formulation 11-2

http://bit.ly/2lojMGi

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 16-2

http://bit.ly/2loocwQ

Current Medicinal Chemistry 24-39

http://bit.ly/2E8r5KN

Current Pharmaceutical Design 23-32

http://bit.ly/2CgJUNz

Current Nanoscience 14-1

http://bit.ly/2lpc0fj

Recent Patents on Biotechnology 12-1

http://bit.ly/2DudNam

 recent-issues

New Issue :: Recent Patents on Biotechnology 11, Issue 3

Recent Patents on Biotechnology publishes review and research articles, and guest edited thematic issues on recent patents in the field of biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.

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Articles from the journal Recent Patents on Biotechnology, Volume 11, Issue 3:

For details on the articles, please visit this link :: http://bit.ly/2zi4Akk

 

 

 

Upcoming Thematic Issue – Anti-virulence approach with Quorum Sensing as the Major Target for dealing with the problem of Antibiotic Resistance – Recent Patents on Biotechnology

RPB-THEMATIC FLYER -Vijay Kothari

http://benthamscience.com/journals/recent-patents-on-biotechnology/special-issues

 

New Issue :: Recent Patents on Biotechnology 11, Issue 1

Recent Patents on Biotechnology publishes review and research articles, and guest edited thematic issues on recent patents in the field of biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.

Recent Biotechnology.jpg

Articles from the journal Recent Patents on Biotechnology 11, Issue 1:

                       For details on the articles, please visit this link :: http://bit.ly/2qdtCLK

Wishing A Very Happy Birthday To Dr. Nikolaos Labrou!

38084-O1K4KU

Dr. Nikolaos Labrou

Editor-in-Chief: Recent Patents on Biotechnology

Laboratory of Enzyme Technology, Department of Biotechnology
Agricultural University of Athens,
Athens,
Greece

Highlighted Article Flyer for the journal “Recent Patents on Biotechnology”

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http://benthamscience.com/journals/recent-patents-on-biotechnology/

New Issue :: Recent Patents on Biotechnology 10, Issue 3

Recent Patents on Biotechnology publishes review and research articles, and guest edited thematic issues on recent patents in the field of biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.

recent-biotechnology

Articles from the journal Recent Patents on Biotechnology 10, Issue 3:

               For details on the articles, please visit this link :: http://bit.ly/2j7rn9v

Highlighted Article Flyer for the journal “Recent Patents on Biotechnology”

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http://benthamscience.com/journals/recent-patents-on-biotechnology/