Animated Abstract | Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps

Extend the scope and visibility of your research by creating an animated abstract.

 

Bentham Science has collaborated with Focus Medica, one of the world’s largest publishers of expert animated atlases and videos in medicine and science.

An animated abstract will help summarise the essential discoveries/ key findings of your published research or review article. Each professionally produced full-coloured animated abstract in video format (length 3 – 5 minutes) is accompanied by an English spoken or foreign language commentary. The animated abstract will be published online along with the published article.

The payment for an animated abstract will be US$ 1400 for English language, and US$ 1900 for Foreign language articles. Initially, an advance payment of US$ 500 of the total payment will be payable to the Publisher to start work on the Animated Abstract, US$ 900 (English language) or US$ 1400 (Foreign language) will be payable on completion of the Animated Abstract.

Authors who opt for the “Animated Abstract” option and also wish to have their article made available on an “Open Access Plus” basis will be entitled to a 50% discount only on the Animated Abstract fee and, in addition, pay the normal Open Access Plus fee.

Authors will be asked whether they wish to opt-in for this paid service, and if not, the article will be published as normal. Animated abstracts are available as open access (free viewing) for maximum visibility and awareness to your readers at anytime, anywhere. The animated abstracts are licensed under the terms of the Creative Commons Attribution – NonCommercial-NoDerivatives 4.0 International Public License (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/.

One of our animated abstracts can be viewed below:

Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps

Journal Name: Current Medicinal Chemistry

Author(s): Hannah Y. Mahmood, Shirin Jamshidi, J. Mark Sutton, Khondaker M. Rahman.

 

 

 

Antimicrobial resistance represents a significant challenge to future healthcare provision.An acronym ESKAPEE has been derived from the names of the organisms recognised as the major threats although there are a number of other organisms, notably Neisseria gonorrhoeae, that have become equally challenging to treat in the clinic. These pathogens are characterised by the ability to rapidly develop and/or acquire resistance mechanisms in response to exposure to different antimicrobial agents. A key part of the armoury of these pathogens is a series of efflux pumps, which effectively exclude or reduce the intracellular concentration of a large number of antibiotics, making the pathogens significantly more resistant. These efflux pumps are the topic of considerable interest, both from the perspective of basic understanding of efflux pump function, and its role in drug resistance but also as targets for the development of novel adjunct therapies. The necessity to overcome antimicrobial resistance has encouraged investigations into the characterisation of resistance-modifying efflux pump inhibitors to block the mechanisms of drug extrusion, thereby restoring antibacterial susceptibility and returning existing antibiotics into the clinic. A greater understanding of drug recognition and transport by multidrug efflux pumps is needed to develop clinically useful inhibitors, given the breadth of molecules that can be effluxed by these systems. This review discusses different bacterial EPIs originating from both natural source and chemical synthesis and examines the challenges to designing successful EPIs that can be useful against multidrug resistant bacteria. To know more about our Animated Abstract, please visit: http://www.eurekaselect.com/video.html

Thought of the Day!

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Thought of the Day!

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Highlighted Article Flyer for the journal “Current Computer-Aided Drug Design”

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http://benthamscience.com/journals/current-computer-aided-drug-design/

Upcoming Thematic Issue – Brain Imaging with Positron Emission Tomography: Novel Radiopharmaceutical

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   http://benthamscience.com/journals/current-medicinal-chemistry/

 

Dishonesty and Being Triumphant – Direct Relation Found

Dishonesty is a behavior that you can expect from nearly all of the people who surround you. Regardless of how much you know anyone, you can never be sure how that person would act in various situations – especially in uncommon scenarios. Social scientists have been deeply interested in knowing what triggers this unethical conduct.

Win-a-Cross-Country-Race-Step-8.jpgRecently studies conducted by scientists in Israel’s Ben-Gurion University of the Negev (BGU) and The Hebrew University of Jerusalem found that dishonesty is quite directly related to winning competitions. Surprisingly, when we you win a competition beating the other opponents, you feel you have earned a right to cheat. This occurs with the idea that victory gives you a sense of entitlement to be superior to others. In tendon you feel the need to cross others on every front. This builds the attitude of cheating and applying any means to achieve this desire.

This research has challenged all those who vote for increasing competition among people, highlighting that it gives rise to bad intent in yourself.

Recently Published Issue of The Journal: Current Pharmaceutical Analysis

Current Pharmaceutical Analysis publishes expert reviews and original research articles on all the most recent advances in pharmaceutical and biomedical analysis. All aspects of the field are represented including drug analysis, analytical methodology and instrumentation. The journal is essential to all involved in pharmaceutical, biochemical and clinical analysis.

Following are the articles recently published in the journal Current Pharmaceutical Analysis, 11 Issue 01:

Article: The Site-specific Protonation Constants of Spectinomycin, Characterized by 1H and 15N NMR Methods  

Author(s): Mate Somlyay, Gabor Orgovan and Bela Noszal

Article: Application of Droplet Size Analysis for the Determination of the Required HLB of Lemon Oil in O/W Emulsion

Author(s): N.A. Niczinger, N. Kallai-Szabo, J. Dredan, L. Budai, M. Hajdu and I. Antal

 

Article: Electrochemical Analysis of Cyanuric Acid Using Polyaniline/CuGeO3 Nanowires as Electrode Modified Materials

Author(s): L.Z. Pei, H.D. Liu, N. Lin, Y.K. Xie and Z.Y. Cai

 

Article: Simultaneous Analysis of Losartan Potassium and its Related Impurities and Degradation Products in Tablets Using HPLC

Author(s): Shuhong Qiu, Kai Liu, Panqin Ma, Menglin Wang, Hongming Chen, Xiaochao Xu, Xiaoli Hao and Yongjun Wang

Article: LC-MS/MS Assay for Quantification of a Novel Antitubercular Molecule S006-830: Pharmacokinetic and Plasma Protein Binding Studies in Rats

Author(s): Mahendra Kumar Hidau, Yeshwant Singh, Sudhir Shahi, Poojari Mounika and Shio Kumar Singh

 

Article: Method Development & Validation of LCMS/MS for Atorvastatin and Olmesartan in Human Plasma to Trace Drug Interaction of Formulation          

Author(s): Rakesh Das and T.K. Pal

 

Article: The Effect of Albumin-genotype on Ibuprofen Displacement of Nifedipine from its Binding Sites.

Author(s): Eman Atef and Ahmed S. Mehanna

 

Article: High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction

Author(s): Andreja Trpkovic, Julijana Stanimirovic, Ivana Resanovic, Petar Otasevic, Danimir Jevremovic, Radak Djordje and Esma R. Isenovic

 

Article: Analysis of Tocopherols and Tocotrienols in Pharmaceuticals and Foods: A Critical Review

Author(s): Dan Lu, Yi Yang, Yongxin Li and Chengjun Sun

For details, please visit: http://bit.ly/1BjtM3A

 

Recent issue of the Journal Current Stem Cell Research & Therapy has been published

Current Stem Cell Research & Therapy, 10 Issue 1

Aims & Scope

Current Stem Cell Research & Therapy publishes high quality frontier reviews, drug clinical trial studies and guest edited issues on all aspects of basic research on stem cells and their uses in clinical therapy. The journal is essential reading for all researchers and clinicians involved in stem cells research

http://www.eurekaselect.com/126318/issue/1

Abstracted & Indexed in:

Journal Citation Reports/Science Edition, Index to Scientific Reviews®, Science Citation Index Expanded (SciSearch®), BIOSIS Previews, BIOSIS Reviews Reports and Meetings, Chemical Abstracts, MEDLINE/PubMed, Scopus, EMBASE, PubsHub., Genamics JournalSeek, MediaFinder®-Standard Periodical Directory, and J-Gate.

For more details please visit: http://benthamscience.com/journal/index.php?journalID=cscrt

BSP Patent Journals: ‘Recent Patents on Biotechnology’ and ‘Recent Patents on Catalysis’

Editor-in-Chief:

ImageRongling Wu

Departments of Public Health Sciences and Statistics
Pennsylvania State College of Medicine
Hershey, PA
USA

Aims & Scope

Recent Patents on Biotechnology publishes review and research articles, and guest edited thematic issues on recent patents in the field of biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.

Editor-in-Chief:

ImageShaobin Wang

Department of Chemical Engineering
Curtin University of Technology
Perth, WA 6845
Japan

Aims & Scope

Recent Patents on Catalysis publishes review, research articles and guest edited thematic issues on recent patents in the field of catalysis. The journal aims to provide recent patent information in all areas of catalysis science, including heterogeneous, homogeneous catalysis, synthesis and properties of new catalysts including synthesis and catalytic function of novel inorganic solids and complexes, studies that relate catalytic function to fundamental chemical processes in metal complexes and at surfaces, novel concepts in surface chemistry. A selection of important and recent patents on catalysis is also included in the journal. The journal is essential reading for all academic and industrial researchers, including IP authorities who wish to be kept informed about important patent breakthroughs in catalysis science and technology.

Bentham Science Publishers’ Journal: Applied Clinical Research, Clinical Trials and Regulatory Affairs

Journal Name: Applied Clinical Research, Clinical Trials and Regulatory Affairs

ISSN: 2213-4778 (Online)
ISSN: 2213-476X (Print)

Volume 1, 3 Issues, 2014

Editor-in-Chief:
Satish Chandra
Tawam Hospital
Al Ain
UAE

Aims & Scope

Applied Clinical Research, Clinical Trials and Regulatory Affairs is an international journal with market leadership in readership and contributions that are scientific, original, relevant, innovative and statistically validated. The journal aims to further bridge the gap in the publication of clinical drug development and regulatory affairs between high growth and potentially growing regions.

The journal Applied Clinical Research, Clinical Trials and Regulatory Affairs publishes innovative, developmental and original research on validated experimental design, methods, representation and interpretation of clinical research and drug trials. Additionally, the journal publishes original research articles, reviews, short communications and thematic journal issues. Published work is based on solid clinical, scientific and statistically relevant results that lead to advancements in clinical medicine, clinical research, regulatory affairs and human subject protection in the areas of biological advances, drugs, bio-therapeutics and devices.

For details on the journal, please visit: Applied Clinical Research, Clinical Trials and Regulatory Affairs

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