Wishing you a very Happy Birthday | Dr. Bin Wu

Dr. Bin Wu serves as the Editor-in-Chief of the Journal The Natural Products Journal

 

Bin Wu
Zhejiang University
Hangzhou
China

Editor’s Choice Article | Chemistry and Biology of Secondary Metabolites from Aspergillus Genus

Author(s): Xiaolei Zhang, Zhi Li, Jiangtao Gao*.

Journal Name: The Natural Products Journal

Abstract: Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the genus produces a wide range of structurally diverse secondary metabolites that are of highly considerable interest to both scientific research community and pharmaceutical industry. Genome sequencing results have indicated that chemical diversity of secondary metabolites is much larger in each species than previously thought.

This review summarizes a total of 315 new secondary metabolites of Aspergillus reported from 2015 to 2017 and demonstrates the therapeutical potential of this genus by introducing their unique chemical structures and excellent bioactivities from this genus. Read out full article here: http://www.eurekaselect.com/161751/article

 

New Issues of various Bentham Science Journals

 

1. Mini-Reviews in Medicinal Chemistry, Vol: 18, Issue: 16

https://bit.ly/2qCXROI

2. Mini-Reviews in Medicinal Chemistry, Vol: 18, Issue: 17

https://bit.ly/2qBcaDd

3. Current Drug Targets, Vol: 19, Issue: 13

https://bit.ly/2QttYLL

4. Current Drug Metabolism, Vol: 19, Issue: 10

https://bit.ly/2qAdypw

5. Current Cancer Drug Targets, Vol: 18, Issue: 8

https://bit.ly/2z3e6sN

6. Current Pharmaceutical Analysis, Vol: 14, Issue: 6

https://bit.ly/2PNXYVE

7. The Natural Products Journal, Vol: 8, Issue: 3

https://bit.ly/2yYGJY6

8. Current Organocatalysis, Vol: 5, Issue: 2

https://bit.ly/2RKY65t

9. Current Drug Safety, Vol: 13, Issue: 3

https://bit.ly/2OvKMjC

10. Current Topics in Medicinal Chemistry, Vol: 18, Issue: 12

https://bit.ly/2D9ecSA

 

RECENTLY PUBLISHED ISSUES – BENTHAM SCIENCE JOURNALS

Drug Metabolism Letters Volume 11, Issue 2
http://bit.ly/2orT9Sl

Current Organic Synthesis Volume 14, Issue 8
http://bit.ly/2CCUR8s

Current Drug Targets Volume 19, Issue 3
http://bit.ly/2F1CWgO

The Natural Products Journal Volume 8, Issue 1
http://bit.ly/2CEDqEr

Current Topics in Medicinal Chemistry Volume 17, Issue 30
http://bit.ly/2CffL1C

Current Pharmaceutical Design Volume 23, Issue 37
http://bit.ly/2CdHbF3

WISHING A VERY HAPPY BIRTHDAY TO DR. BIN WU!

DR. BIN WU

EDITOR-IN-CHIEF: The Natural Products Journal
Zhejiang University
Hangzhou
China

Highlighted Article – Essential Oil Composition, In Vivo Antioxidant, and Antimicrobial Activities of Pimpinella pruatjan from West Java, Indonesia – The Natural Products Journal

http://www.eurekaselect.com/153444

New Issue :: The Natural Products Journal 7, Issue 1

The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products.

The Natural Products Journal publishes original research articles, reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.

Articles from the journal The Natural Products Journal 7, Issue 1:

• Horn’s Biologically Active Substances – Can We Replace Horns of Critically Endangered Species (Saiga) by Horns of More Abundant Animals?
• An Efficient Method for Olive Leaves Proteins Extraction and Two- Dimensional Electrophoresis
• Guar Gum and HPMC Coated Colon Targeted Delivery of 6-Mercapto-Purine
• Reflux Extraction and Column Chromatography for Rosmarinic Acid- Rich Fraction from Orthosiphon stamineus
• Ameliorative Potential of Cymbopogon citratus Decoctions on Gasoline Vapour-Induced Nephrotoxicity
• Hypoglycemic and Hypolipidemic Effects of Aqueous Extracts of Ajuga iva and Centaurium erythreae on a Rodent Model of Metabolic Syndrome
• Chemical Composition and Physical Characteristics of Clones of the Ume (Prunus mume Siebold et Zucc.)
• Total Phenolic Content, Volatile Constituents and Antioxidative Effect of Coriandrum sativum, Murraya koenigii and Mentha arvensis
• Physical-chemical and Biochemical Properties of Rama Forte Persimmons Submitted to UV-C Radiation

For details on the articles, please visit this link :: http://bit.ly/2mc1ytT

Wishing A Very Happy Birthday To Dr. Francesco Epifano!

Dr. Francesco Epifano

Editor-in-Chief: The Natural Product Journal

Università “G. D’Annunzio”
Chieti-Pescara, Chieti Scalo (CH),
Italy

Press Release for EurekAlert! A novel anticandidal compound containing sulfur from endophytic fungus

There is a continuous search for new, safe and relatively cheaper drugs with the advent of new diseases and increasing antibiotic resistance. Endophtyes having the potential to synthesize a wide array of bioactive compounds is an attractive alternative. They have the potential not only to synthesize plant metabolites but also a host of other natural products exhibiting a broad spectrum of structural and chemical diversities exhibiting biological activity and therefore can serve as lead molecule(s) for designing new drugs.

In the present study, an endophytic fungus Emericella sp., was isolated from its host plant Azadirachta indica growing in semi-arid regions of Rajasthan, India. The fungal biomass was subjected to organic extraction. Hexane, ethyl acetate, ethanol and methanol were used as solvents. Ethanolic extract from the biomass exhibited anticadidal activity. Candida species are known to produce a wide spectrum of diseases including superficial mucocutaneous diseases and invasive illnesses like hepatosplenic candidiasis, candida peritonitis and systemic candidiasis. The anticandidal compounds known till date belong to allyiamine, azole and polyene classes. In the present study, the isolated compound was identified to be be a sulphur containing compound – N-[2S,3aR, 6S, 7aS)-6-acetamido-octahydro-1,3-benzothiazol-2-yl]2-(adamantan-1-yl) acetamide. Hence, this novel sulphur containing molecule, synthesized by Emericella sp. can serve as a lead molecule for designing new drugs having anticandidal activity. Similarly, the bioprospecting of entophytes from unexplored biological niches can serve as a source of lead molecules for developing novel and/or designer molecules for industrial applications.

Reference: Shweta, M.; et al (2016). A Novel Anticandidal Sulphur Containing Molecule from Emericella Sp. Endophytic to Azadirachta indica. Natural Product Journal., DOI: 10.2174/2210315506666160513160732

For More Information about the article, please visit: http://benthamscience.com/journals/the-natural-products-journal/volume/6/issue/3/page/188/

New Issue :: The Natural Products Journal 6, Issue 4

The Natural Products Journal a peer reviewed journal,  aims to publish all the latest and outstanding developments in natural products.

The Natural Products Journal publishes original research articles, reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.

Articles from the journal The Natural Products Journal 6, Issue 4:

• Lecithin (Phosphatidylcholine): Healthy Dietary Supplement or Dangerous Toxin?
• Therapeutic Potential of Plant Extracts and Phytochemicals Against Brain Ischemia-Reperfusion Injury: A Review
• An Overview on Phytochemical and Pharmacological Aspects of Echium amoenum
• In Silico Identification of Natural Lead Molecules from the Genus of Phyllanthus Against Hepatitis B Virus Reverse Transcriptase
• Effect of Boswellia serrata Extract Microcapsule Against Ulcerative Colitis in Mice
• Herbivory Causes Chemical and Biological Changes on Essential Oil from Piper marginatum Leaves

               For details on the articles, please visit this link :: http://bit.ly/2hQ27IF