New Issue | MicroRNA; Volume 9 Issue 1

 

 

MicroRNA publishes letters, full-length/ mini reviews, research articles, drug clinical trial studies and thematic issues on all aspects of microRNA (miRNA) research. The scope of the journal covers all experimental miRNA research and applied research in health and disease, including therapeutic, biomarkers, and diagnostic applications of MiRNA.

 

Articles from the journal: MicroRNA; Volume 9 Issue 1

• The Role of microRNAs Identified in the Amniotic Fluid
• Updates on the Current Technologies for microRNA Profiling open access plus
• Role of MicroRNA in the Diagnosis and Management of Hepatocellular Carcinoma open access plus
• Neglected Tropical Diseases: The Potential Application of microRNAs for Monitoring NTDs in the Real World open access plus
• The Promising Signatures of Circulating microRNA-145 in Epithelial Ovarian Cancer Patients
• Overexpression of microRNA-21 in the Serum of Breast Cancer Patients
• The KLF6 Super Enhancer Modulates Cell Proliferation via MiR-1301 in Human Hepatoma Cells
• Hotspot Mutations in DICER1 Causing GLOW Syndrome-Associated Macrocephaly via Modulation of Specific microRNA Populations Result in the Activation of PI3K/ATK/mTOR Signaling open access plus

For details on the articles, please visit this link: http://www.eurekaselect.com/node/99280/microrna-/issue/9/2680/1/9490

Call for Papers | Current Pharmaceutical Design

Special Thematic Issues | Forthcoming Issues

Journal: Current Pharmaceutical Design

 

Guest Editor(s): Celestino Sardu
Tentative Publication Date: January, 2020

 

“Metabolic Syndrome impact on molecular, and cellular functions in patients affected by heart failure: therapeutic, diagnostic and clinical applications”

 

In this Special Issue we would try to bring the two major diseases together by focusing on common molecular pathways, mechanisms and subsequently on clinical outcomes. We may speculate that, the identification of mechanisms underlying the pathophysiology of MS and its CV complications may represent an area of significant research efforts, attracting scientists and clinicians from a diverse range of fields including biochemistry, pharmacology, internal medicine, cardiology and geriatrics among several others.Our Special Issue hypothesis is that, the final goal in the near future will be to find treatments better tailored to MS patients with HF using a personalized–medicine approach. Therefore, here we invite investigators to submit to this Special Issue both original research articles, clinical trials and reviews having the purpose to address novel diagnostic tools or new therapeutic treatments for MS and HF. For more details please visit: https://benthamscience.com/journal-files/special-issue-details/CPD-SII20181228-01.pdf

 

To submit your paper, email at: hermain@benthamscience.net and CC: faizan@benthamscience.net

Article by Disease | Therapeutic Utilities of Pediatric Cardiac Catheterization

 

Bentham Cardiovascular Disorders Collection | Cardiovascular Disorders | Aortic Coarctation 

Therapeutic cardiac catheterization constantly evolves and widens its spectrum of usage in the pediatric population. The advent of sophisticated devices and well-designed equipment has made the management of many congenital cardiac lesions more efficient and safer, while providing more comfort to the patient.

 

 

Read out more at: http://www.eurekaselect.com/node/139921/article

MOST ACCESSED ARTICLE – Mesenchymal Stem Cells-Derived Exosomes: A Possible Therapeutic Strategy for Osteoporosis

Journal Name: Current Stem Cell Research & Therapy

Author(s): Yue Li, Daxiang Jin*, Weixing Xie, Longfei Wen, Weijian Chen, Jixi Xu, Jinyong Ding, Dongcheng Ren, Zenglin Xiao.

 

 

 

Abstract:

Osteoporosis is a common age-related disorder characterized by low bone mass and deterioration in bone microarchitecture, leading to increased skeletal fragility and fracture risk. The pathophysiology of osteoporosis is multifactorial. It is related to the imbalance between osteoblasts and osteoclasts; reduced bone mass and increased adipogenesis in the bone marrow. Moreover, angiogenesis, inflammatory process and miRNAs have shown effects in the formation of osteoporosis. In the recent years, mesenchymal stem cells (MSCs) have been regarded as an excellent choice for cell-based tissue engineering therapy of osteoporosis. Growing evidence showed that paracrine effect has been considered as the predominant mechanism for the role of MSCs in tissue repair. Recently, many studies have proposed that MSCs-derived exosomes are effective for a variety of diseases like cancer, cardiovascular diseases, etc. However, whether the MSCs-derived exosomes could serve as a novel therapeutic tool for osteoporosis has not clearly described. In this review, we summarize the MSCs-derived exosomes and the relationship with osteogenesis, osteoclast differentiation, angiogenesis, immune processes and miRNAs. Finally, we suggest that MSCs-derived exosomes might be a promising therapeutic method for osteoporosis in the future.

 

For more details, please visit: http://www.eurekaselect.com/160963