Today is World Polio Day, 2019!

Bentham Science publishes articles related to World Polio Day in its Subscription based journals including:

  1. – Recent Patents on Anti-Infective Drug Discovery

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World Polio Day

World Polio Day was established by Rotary International over a decade ago to commemorate the birth of Jonas Salk, who led the first team to develop a vaccine against poliomyelitis. Use of this inactivated polio-virus vaccine and subsequent widespread use of the oral polio-virus, developed by Albert Sabin, led to the establishment of the Global Polio Eradication Initiative (GPEI) in 1988. As of 2013, GPEI had reduced polio worldwide by 99%.

Polio is a crippling and potentially fatal infectious disease. There is no cure, but there are safe and effective vaccines. Polio can be prevented through immunization. Polio vaccine, given multiple times, almost always protects a child for life. The strategy to eradicate polio is therefore based on preventing infection by immunizing every child until transmission stops and the world is polio-free.

ARTICLE TO READ ON WORLD POLIO DAY, 2018!

Polio and its Vaccination: A Cross Sectional Study of Knowledge, Attitude and Perception of General Public in district Abbottabad and Mansehra, Khyber Pakhtunkhwa, Pakistan

 

Author(s): Humaira Saeed, Saira Azhar*, Akash Syed, Saliha Khalid, Annum Bukhari,Nidda Saeed.

 

 

Graphical Abstract:

 

Abstract:

Background: According to global eradication initiative program, poliomyelitis was eradicated all over the world except Pakistan and Afghanistan due to some challenges like misconceptions, non-compliances, political and militancy issues, etc.

Objective: This study quantitatively evaluates the knowledge, attitude and perception of general public regarding polio and its vaccination in district Abbottabad and Mansehra, KPK, Pakistan.

Method: A cross sectional study design involving 800 participants was conducted from November 2015 to February 2016 in district Abbottabad and Mansehra of KPK, Pakistan. To collect the data from eligible participants, pre tested self-administered questionnaire was used. Descriptive and binary logistic regression analysis was used to express the results of the study.

Results: A total of 53.8% participants exhibited appropriate knowledge about polio and its vaccination. Higher qualification (p<0.001), urban locality (p<0.05), paid employed (p<0.05) and primary information source (p<0.001) were significantly associated with appropriate knowledge of polio and its vaccination. About 71.6% of the participants showed positive attitude towards polio and its vaccination. Older age (p<0.001), self-employment (p<0.05), high income (p<0.001), urban residence (p<0.001) and primary information source i.e. village and community leaders (p<0.05) were significantly associated with the positive attitudes of participants towards polio and its vaccination. About 56.90% participants had wrong perception about which treatment is best for polio. Overall perception about polio and its vaccination was significantly associated with participants of older age (p<0.001), gender specially females (p<0.05), employment status i.e. self- employment (p<0.001), higher income (p<0.001), marital status (p<0.05) and urban residency (p<0.05).

Conclusion: This study identified some important issues related to polio vaccination which can help in eradicating polio by effective immunization campaigns in Pakistan.

 

For more details, please visit: http://www.eurekaselect.com/159437

World Polio Day, 2018!

 

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World Polio Day was established by Rotary International over a decade ago to commemorate the birth of Jonas Salk, who led the first team to develop a vaccine against poliomyelitis. Use of this inactivated poliovirus vaccine and subsequent widespread use of the oral poliovirus, developed by Albert Sabin, led to the establishment of the Global Polio Eradication Initiative (GPEI) in 1988. As of 2013, GPEI had reduced polio worldwide by 99%.

Polio is a crippling and potentially fatal infectious disease. There is no cure, but there are safe and effective vaccines. Polio can be prevented through immunization. Polio vaccine, given multiple times, almost always protects a child for life. The strategy to eradicate polio is therefore based on preventing infection by immunizing every child until transmission stops and the world is polio-free.

 

Bentham Science publishes articles related to World Polio Day in its Subscription based journals including:

 

 

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World Polio Day 2017!

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World Polio Day is annually observed on 24th October. Polio is a crippling and potentially fatal infectious disease. Polio can be prevented through immunization. Polio vaccine, given multiple times, almost always protects a child for life. The strategy to eradicate polio is therefore based on preventing infection by immunizing every child until transmission stops and the world is polio-free.

Bentham Science publishes very important research related to this day in the following journals:

Infectious Disorders – Drug Targets 

To Avail 20% Discount on related eBooks, kindly visit: https://ebooks.benthamscience.com/

Article by disease – “The Yin and Yang of Antiviral Innate Immunity in Central Nervous System”

Article by disease on “Polio”

Abstract: The innate immune system provides protection against invading neurotropic viruses. It acts as the first line of defense against invading viruses and plays an elementary role in their pathogenesis. The list of viruses capable of infecting human central nervous system (CNS) is quite long, most important of them are Japanese Encephalitis virus (JEV), rabies virus, West Nile virus (WNV), herpes simplex virus (HSV), St. Louis encephalitis virus (SLEV), La Crosse virus, tick borne encephalitis virus (TEBE) and polio virus. Germ line pattern recognition receptors (PRRs) such as Toll like receptors (TLRs), nucleotide binding oligomerization domain (NOD) – like receptors (NLRs), retinoic acid-inducible gene I (RIG-I) -like helicases or RIG-I-like receptors (RLRs) and cytosolic DNA sensors recognize the pathogen associated molecular patterns (PAMPs) and initiate an immune response against invading pathogen. Although PRRs were originally characterized in peripheral immune cells but accumulating evidence also suggest their crucial roles in CNS to combat against neurotropic viruses. In this review, we will highlight the recent developments in our understating of the mechanisms by which PRRs in resident brain cells provide protection against invading neurotropic viruses.

Read more details: http://benthamscience.com/journals/current-pharmaceutical-design/volume/22/issue/6/page/648/

World Polio Day!

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Bentham Science stands with Polio patients on the World Polio Day, 24th October 2016. Find the latest research papers published in our journals that focus on Polio and its treatments. The most significant one is:

http://benthamscience.com/journals/infectious-disorders-drug-targets/

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