Background: Propofol, a widely used intravenous anesthetic agent, is traditionally applied for sedation and general anesthesia.
Explanation: Recent attention has been drawn to explore the effect and mechanisms of propofol against cancer progression in vitro and in vivo. Specifically, the proliferation-inhibiting and apoptosis-inducing properties of propofol in cancer have been studied. However, the underlying mechanisms remain unclear.
Conclusion: This review focused on the findings within the past ten years and aimed to provide a general overview of propofol’s malignance-modulating properties and the potential molecular mechanisms.
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